Retrovirus-mediated gene transfer into CD4+ and CD8+ human T cell subsets derived from tumor-infiltrating lymphocytes and peripheral blood mononuclear cells

Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.

1968 • 5,084 citations

Use of Tumor-Infiltrating Lymphocytes and Interleukin-2 in the Immunotherapy of Patients with Metastatic Melanoma

1988 • 2,196 citations

A New Approach to the Adoptive Immunotherapy of Cancer with Tumor-Infiltrating Lymphocytes

1986 • 1,787 citations

Gene Transfer into Humans — Immunotherapy of Patients with Advanced Melanoma, Using Tumor-Infiltrating Lymphocytes Modified by Retroviral Gene Transduction

1990 • 1,307 citations

Redesign of Retrovirus Packaging Cell Lines To Avoid Recombination Leading to Helper Virus Production

1986 • 1,276 citations

Construction and applications of a highly transmissible murine retrovirus shuttle vector

1984 • 1,020 citations

Redesign of retrovirus packaging cell lines to avoid recombination leading to helper virus production.

1986 • 828 citations

Expression of a foreign gene in myeloid and lymphoid cells derived from multipotent haematopoietic precursors

1985 • 598 citations

Identification of specific cytolytic immune responses against autologous tumor in humans bearing malignant melanoma.

1987 • 478 citations

Evidence that the packaging signal of Moloney murine leukemia virus extends into the gag region

1987 • 426 citations

CARCINOID SYNDROME

1961 • 405 citations

A new sensitive method for qualitative and quantitative assay of neomycin phosphotransferase in crude cell extracts

1984 • 398 citations

Expansion of human tumor infiltrating lymphocytes for use in immunotherapy trials

1987 • 361 citations

TUMOUR-INFILTRATING LYMPHOCYTES AND INTERLEUKIN-2 IN TREATMENT OF ADVANCED CANCER

1989 • 337 citations

Tumor localization of adoptively transferred indium-111 labeled tumor infiltrating lymphocytes in patients with metastatic melanoma.

1989 • 332 citations

Interleukin 2 expanded tumor-infiltrating lymphocytes in human renal cell cancer: isolation, characterization, and antitumor activity.

1988 • 302 citations

Gene Expression in Mice After High Efficiency Retroviral-Mediated Gene Transfer

1985 • 281 citations

Interleukin 2 activation of cytotoxic T-lymphocytes infiltrating into human metastatic melanomas.

1986 • 259 citations

Retroviruses as mutagens: Insertion and excision of a nontransforming provirus alter expression of a resident transforming provirus

1981 • 253 citations

In Vivo Antitumor Activity of Tumor-Infiltrating Lymphocytes Expanded in Recombinant Interleukin-2

1987 • 250 citations

The integrated genome of murine leukemia virus

1978 • 232 citations

Retrovirus transfer of a bacterial gene into mouse haematopoietic progenitor cells

1983 • 214 citations

Quantitation and Cloning of Cytolytic T Lymphocytes and their Precursors

1980 • 213 citations

Retrovirus-mediated transfer and expression of drug resistance genes in human haematopoietic progenitor cells

1986 • 213 citations

Retrovirus-mediated transfer of human adenosine deaminase gene sequences into cells in culture and into murine hematopoietic cells in vivo.

1986 • 194 citations

Expression of human adenosine deaminase in nonhuman primates after retrovirus-mediated gene transfer.

1987 • 187 citations

Correction of adenosine deaminase deficiency in cultured human T and B cells by retrovirus-mediated gene transfer.

1986 • 168 citations

Human gene transfer: characterization of human tumor-infiltrating lymphocytes as vehicles for retroviral-mediated gene transfer in man.

1990 • 145 citations

Infection efficiency of T lymphocytes with amphotropic retroviral vectors is cell cycle dependent

1989 • 129 citations

Local administration of cells containing an inserted IL-2 gene and producing IL-2 inhibits growth of human tumours in nu/nu mice

1988 • 79 citations

Improved retroviral transfer of genes into canine hematopoietic progenitor cells kept in long-term marrow culture

1989 • 55 citations

Differences in activities of murine retroviral long terminal repeats in cytotoxic T lymphocytes and T-lymphoma cells

1989 • 32 citations

Retroviral-mediated gene transfer into mammalian cells.

1987 • 31 citations

Augmentation of tumor targeting in a line of glioma-specific mouse cytotoxic T-lymphocytes by retroviral expression of mouse gamma-interferon complementary DNA.

1988 • 24 citations

Gene transfer into hemopoietic stem cells using retroviral vectors

1989 • 19 citations

High efficiency gene transfer into murine T cell clones using a retroviral vector.

1986 • 13 citations

Introduction of a selectable gene into murine T-lymphoblasts by a retroviral vector

1986 • 8 citations

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