Ubiquitylation and Isgylation: Overlapping Enzymatic Cascades Do the Job

Polymeric Chains of SUMO-2 and SUMO-3 Are Conjugated to Protein Substrates by SAE1/SAE2 and Ubc9

2001 • 782 citations

The ubiquitin-like protein Smt3p is activated for conjugation to other proteins by an Aos1p/Uba2p heterodimer

1997 • 543 citations

Mdm2-Mediated NEDD8 Conjugation of p53 Inhibits Its Transcriptional Activity

2004 • 541 citations

Ubc9p Is the Conjugating Enzyme for the Ubiquitin-like Protein Smt3p

1997 • 488 citations

The interferon-inducible 15-kDa ubiquitin homolog conjugates to intracellular proteins.

1992 • 420 citations

A superfamily of protein tags: ubiquitin, SUMO and related modifiers

2003 • 367 citations

A novel protein modification pathway related to the ubiquitin system

1998 • 361 citations

Ubiquitination and Endocytosis of Plasma Membrane Proteins: Role of Nedd4/Rsp5p Family of Ubiquitin-Protein Ligases

2000 • 356 citations

Protein ISGylation modulates the JAK-STAT signaling pathway

2003 • 313 citations

Accumulation of an mRNA and protein in interferon-treated Ehrlich ascites tumour cells

1979 • 297 citations

The UbcH8 ubiquitin E2 enzyme is also the E2 enzyme for ISG15, an IFN-α/β-induced ubiquitin-like protein

2004 • 295 citations

A new NEDD8-ligating system for cullin-4A

1998 • 249 citations

High-throughput Immunoblotting

2003 • 245 citations

A human 15-kDa IFN-induced protein induces the secretion of IFN-gamma.

1991 • 168 citations

Dysregulation of protein modification by ISG15 results in brain cell injury

2002 • 156 citations

Molecular conservation of 74 amino acid sequence of ubiquitin between cattle and man

1975 • 130 citations

Serpin 2a Is Induced in Activated Macrophages and Conjugates to a Ubiquitin Homolog

2002 • 90 citations