The T‐Cell Receptor for Antigen in T‐Cell Development and Repertoire Selection

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

Identification of a monoclonal antibody specific for a murine T3 polypeptide.

1987 • 1,644 citations

On the thymus in the differentiation of "H-2 self-recognition" by T cells: evidence for dual recognition?

1978 • 870 citations

The major histocompatibility complex-restricted antigen receptor on T cells. I. Isolation with a monoclonal antibody.

1983 • 861 citations

The Molecular Genetics of the T-Cell Antigen Receptor and T-Cell Antigen Recognition

1986 • 772 citations

T Cell Subsets and the Recognition of MHC Class

1983 • 702 citations

Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells.

1983 • 654 citations

In a radiation chimaera, host H–2 antigens determine immune responsiveness of donor cytotoxic cells

1977 • 534 citations

Tumor-specific antigen of murine T-lymphoma defined with monoclonal antibody.

1982 • 526 citations

A new T-cell receptor gene located within the alpha locus and expressed early in T-cell differentiation

1987 • 483 citations

Antigen-like effects of monoclonal antibodies directed at receptors on human T cell clones.

1983 • 435 citations

A T cell receptor Vβ segment that imparts reactivity to a class II major histocompatibility complex product

1987 • 408 citations

Major histocompatibility complex-linked immune-responsiveness is acquired by lymphocytes of low-responder mice differentiating in thymus of high-responder mice.

1978 • 353 citations

Functional interaction between human T-cell protein CD4 and the major histocompatibility complex HLA-DR antigen

1987 • 348 citations

H-2 antigens of the thymus determinelymphocyte specificity

1978 • 321 citations

Aberrant rearrangements contribute significantly to the allelic exclusion of immunoglobulin gene expression

1981 • 319 citations

Early T lymphocytes. Differentiation in vivo of adult intrathymic precursor cells.

1985 • 305 citations

Monoclonal antibodies against the antigen receptor on a cloned T-cell hybrid.

1983 • 293 citations

Identity of cells that imprint H–2-restricted T-cell specificity in the thymus

1986 • 267 citations

Ontogeny of the T-cell antigen receptor within the thymus

1985 • 250 citations

Specific antigen—la activation of transfected human T cells expressing murine Ti αβ —human T3 receptor complexes

1987 • 247 citations

Characterization of murine thymocytes with CDS-associated T-cell receptor structures

1987 • 245 citations

Reconstitution of MHC class I specificity by transfer of the T cell receptor and Lyt-2 genes

1987 • 220 citations

The mouse T cell receptor: Comparison of MHC-restricted receptors on two T cell hybridomas

1983 • 218 citations

Clonal Heterogeneity in the Functional Requirement for Lyt‐2/3 Molecules on Cytolytic T Lymphocytes (CTL): Possible Implications for the Affinity of CTL Antigen Receptors

1982 • 204 citations

Rearrangement of T-cell receptor beta-chain genes during T-cell development.

1985 • 200 citations

A single stem cell can recolonize an embryonic thymus, producing phenotypically distinct T-cell populations

1985 • 199 citations

The T cell receptor: the α and β chains define idiotype, and antigen and MHC specificity

1985 • 198 citations

The differentiation of T lymphocytes

1974 • 185 citations

The major histocompatibility complex-restricted antigen receptor on T cells. IV. An antiidiotypic antibody predicts both antigen and I-specificity.

1983 • 181 citations

Transfection of the CD8 gene enhances T-cell recognition

1987 • 177 citations

Role of the L3T4-antigen in T cell activation. II. Inhibition of T cell activation by monoclonal anti-L3T4 antibodies in the absence of accessory cells.

1985 • 167 citations

The delineation of antigen receptors on human T lymphocytes

1983 • 162 citations

Synergism in the activation of human CD8 T cells by cross-linking the T-cell receptor complex with the CD8 differentiation antigen.

1986 • 159 citations

Thymocytes appear to ignore class I major histocompatibility complex antigens expressed on thymus epithelial cells

1984 • 158 citations

A one-receptor view of T-cell behaviour

1981 • 146 citations

Alloantigen Recognition Is Preceded by Nonspecific Adhesion of Cytotoxic T Cells and Target Cells

1986 • 145 citations

Lyt-2 and lyt-3 antigens are on two different polypeptide subunits linked by disulfide bonds. Relationship of subunits to T cell cytolytic activity.

1981 • 142 citations

The role of H-2 linked genes in helper T-cell function. IV. Importance of T-cell genotype and host environment in I-region and Ir gene expression.

1978 • 134 citations

Differentiation of thymocytes in fetal organ culture: analysis of phenotypic changes accompanying the appearance of cytolytic and interleukin 2-producing cells.

1984 • 131 citations

STUDIES OF THE ROLE OF THE THYMIC ENVIRONMENT IN THE INDUCTION OF TOLERANCE TO MHC ANTIGENS

1985 • 127 citations

A speculative view of the multicomponent nature of T cell antigen recognition

1986 • 117 citations

In a fully H-2 incompatible chimera, T cells of donor origin can respond to minor histocompatibility antigens in association with either donor or host H-2 type.

1978 • 108 citations

The selection of the α,β heterodimeric T-cell receptor for antigen

1986 • 100 citations

Immune responses of thymusf/ymphocyte embryonic chimeras: studies on tolerance and major histocompatibility complex restriction in Xenopus

1985 • 90 citations

The functional capabilities of cells leaving the thymus.

1984 • 84 citations

CD4+ murine T cells develop from CD8+ precursors in vivo

1987 • 71 citations

A clone-specific monoclonal antibody that inhibits cytolysis of a cytolytic T cell clone.

1983 • 59 citations

Monoclonal antibodies specific for a murine cytotoxic T-lymphocyte clone.

1984 • 51 citations

T Cell Function in Bone Marrow Chimeras; Absence of Host‐Reactive T Cells and Cooperation of Helper T Cells across Allogeneic Barriers

1976 • 49 citations

Monoclonal anti-Lyt-2.2 antibody blocks lectin-dependent cellular cytotoxicity of H-2-negative target cells.

1984 • 47 citations

Cell Surface Antigen Marking the Stages of Murine T Cell Ontogeny and its Functional Subsets

1984 • 36 citations

A novel approach for preparing anti‐T cell receptor constant region antibodies

1986 • 34 citations

Expression of T cell receptors by thymocytes: in situ staining and biochemical analysis.

1986 • 33 citations

Differences in the MHC-restricted self-recognition repertoire of intra-thymic and extra-thymic cytotoxic T lymphocyte precursors.

1983 • 32 citations

Restriction molecules involved in the interaction of T cells with allogeneic antigen-presenting cells.

1982 • 22 citations

The role of T-cell receptor α and β genes in MHC-restricted antigen recognition

1986 • 17 citations

Stable expression of Lyt‐2 homodimers on L3T4⁺T cell clones

1986 • 11 citations

Studies on the mechanism of the self restriction of T cell responses in radiation chimeras.

1981 • 8 citations

Host‐Reactive Cytotoxic T Lymphocyte Precursors in Long‐lived Fully Allogeneic Mouse Bone Marrow Chimeras

1986 • 4 citations