Cell Surface Antigen Marking the Stages of Murine T Cell Ontogeny and its Functional Subsets

MHC-Restricted Cytotoxic T Cells: Studies on the Biological Role of Polymorphic Major Transplantation Antigens Determining T-Cell Restriction-Specificity, Function, and Responsiveness

1979 • 1,969 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1984 • 1,239 citations

The "Ly-1 B" cell subpopulation in normal immunodefective, and autoimmune mice.

1983 • 810 citations

A molecular map of the immune response region from the major histocompatibility complex of the mouse

1982 • 466 citations

In vivo effects of anti-asialo GM1. I. Reduction of NK activity and enhancement of transplanted tumor growth in nude mice.

1981 • 424 citations

Properties of the antigen-specific suppressive T-cell factor in the regulation of antibody response of the mouse. IV. Special subregion assignment of the gene(s) that codes for the suppressive T-cell factor in the H-2 histocompatibility complex.

1976 • 376 citations

A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes.

1976 • 353 citations

Identification and initial characterization of a rat monoclonal antibody reactive with the murine interleukin 2 receptor-ligand complex.

1983 • 348 citations

Two distinct types of helper T cells involved in the secondary antibody response: independent and synergistic effects of Ia- and Ia+ helper T cells.

1978 • 316 citations

T-cell regulation of antibody responses: demonstration of allotype-specific helper T cells and their specific removal by suppressor T cells.

1976 • 245 citations

Precursors of T cell growth factor producing cells in the thymus: ontogeny, frequency, and quantitative recovery in a subpopulation of phenotypically mature thymocytes defined by monoclonal antibody GK-1.5.

1983 • 237 citations

The murine IL 2 receptor. I. Monoclonal antibodies that define distinct functional epitopes on activated T cells and react with activated B cells.

1984 • 214 citations

STUDIES ON THE DIFFERENTIATION OF THYMUS-DERIVED LYMPHOCYTES

1970 • 198 citations

θ-bearing Lymphocytes in Nude Mice

1973 • 150 citations

RNA transcripts for I-J polypeptides are apparently not encoded between the I-A and I-E subregions of the murine major histocompatibility complex.

1983 • 145 citations

Specificity of cytotoxic T cells from athymic mice.

1980 • 141 citations

Differentiation of T Cells in Nude Mice

1975 • 134 citations

Selective expression of H-2 (i-region) loci controlling determinants on helper and suppressor T lymphocytes.

1976 • 131 citations

Antigen-specific suppressive factor produced by a transplantable I-J bearing T-cell hybridoma

1979 • 124 citations

A rat monoclonal antibody that binds specifically to mouse T lymphoblasts and inhibits IL 2 receptor functions: a putative anti-IL 2 receptor antibody.

1984 • 121 citations

BRAIN-ASSOCIATED STEM CELL ANTIGEN: AN ANTIGEN SHARED BY BRAIN AND HEMOPOIETIC STEM CELLS

1972 • 120 citations

Suppression of antibody and T cell proliferative responses to L-glutamic acid60-L-alanine30-L-tyrosine10 by a specific monoclonal T cell factor.

1980 • 109 citations

Demonstration that IgG memory is carried by IgG‐bearing cells

1976 • 108 citations

Specific enrichment of the suppressor T cell bearing I-J determinants: parallel functional and serological characterizations.

1977 • 103 citations

Mice whose B cells cannot produce the T15 idiotype also lack an antigen-specific helper T cell required for T15 expression.

1979 • 102 citations

The glycolipid asialo GM1 as a new differentiation antigen of fetal thymocytes.

1980 • 90 citations

Lyt 1+23− cells appear in the thymus before Lyt 123+ cells

1981 • 77 citations

Studies of Generation of B-cell Diversity in Mouse, Man, and Chicken

1977 • 70 citations

Self recognition in allogeneic thymic chimeras. Self recognition by T helper cells from thymus-engrafted nude mice is restricted to the thymic H-2 haplotype.

1982 • 65 citations

Regulation of Immunoglobulin and Antibody Production Allotype Suppressor T Cells in Mice

1975 • 61 citations

Cell-to-cell interaction controlled by immunoglobulin genes. Role of Thy-1-, Lyt-1+, Ig+ (B') cell in allotype-restricted antibody production.

1982 • 61 citations

Primary structural variation among serologically indistinguishable DS antigens: the MB3-bearing molecule in DR4 cells differs from the MB3-bearing molecule in DR5 cells.

1984 • 58 citations

Cell cooperation during in vivo anti‐hapten antibody responses: V. Two synergistic Ly‐1⁺23⁻ helper T cells with distinctive specificities

1980 • 53 citations

Congenitally athymic nude (nu/nu) mice have Thy-1-bearing immunocompetent helper T cells in their peritoneal cavity.

1980 • 49 citations

Functional association of idiotypic and I-J determinants on the antigen receptor of suppressor T cells.

1981 • 49 citations

An idiotype-specific helper population that bears immunoglobulin, Ia, and Lyt-1 determinants.

1984 • 47 citations

Two stages of B-cell memory development with different T-cell requirements.

1976 • 46 citations

Thymic T cells are driven to expand upon interaction with self-class II major histocompatibility complex gene products on accessory cells.

1984 • 33 citations

A mature T lymphocyte subpopulation marker closely linked to the Ig‐1 allotype C_H locus

1979 • 31 citations

Establishment and functional analysis of a cloned, antigen-specific suppressor effector T cell line.

1984 • 23 citations

Photoaffinity-labeled Hapten-binding T-cell receptor on a suppressor T-cell hybridoma

1984 • 21 citations

Ontogeny of murine I-Ak antigens in tissue of nonlymphoid origin

1981 • 13 citations

Idiotypic and fine specificity analysis of a (4‐hydroxy‐3‐nitrophenyl)acetyl (NP)‐specific suppressor T cell hybridoma at the level of cell surface structures, isolated receptor material and functional suppressor factor

1983 • 13 citations

Rat Thy‐1 antigen has a hydrophobic segment at the carboxyl terminus

1984 • 7 citations

CELL LINEAGE OF NK CELL: EVIDENCE FOR T CELL LINEAGE

1982 • 4 citations

Heterogeneity of Igh‐linked allotypic determinants expressed on functional T cell subsets as detected by monoclonal antibodies

1984 • 3 citations