An ATP-dependent system specific for degradation of long-lived proteins in permeabilized cells

Amino Acid Sequences Common to Rapidly Degraded Proteins: The PEST Hypothesis

1986 • 2,566 citations

In Vivo Half-Life of a Protein Is a Function of Its Amino-Terminal Residue

1986 • 1,942 citations

Ubiquitin-lysozyme conjugates. Identification and characterization of an ATP-dependent protease from rabbit reticulocyte lysates.

1986 • 278 citations

ATP-dependent acidification of intact and disrupted lysosomes. Evidence for an ATP-driven proton pump.

1981 • 255 citations

Early events in the stimulation of mammary tumor virus RNA synthesis by glucocorticoids. Novel assays of transcription rates.

1984 • 202 citations

Protein Degradation in Cultured Cells

1973 • 195 citations

ATP serves two distinct roles in protein degradation in reticulocytes, one requiring and one independent of ubiquitin.

1983 • 162 citations

Identification and partial purification of an ATP-stimulated alkaline protease in rat liver.

1979 • 149 citations

A mild procedure for the rapid release of cytoplasmic enzymes from cultured animal cells

1979 • 144 citations

Requirement for protein synthesis in the regulation of protein breakdown in cultured hepatoma cells

1975 • 125 citations

The ATP dependence of the degradation of short- and long-lived proteins in growing fibroblasts.

1985 • 113 citations

Minireview: Mechanisms of protein turnover in cultured cells

1981 • 104 citations

A soluble ATP-dependent system for protein degradation from murine erythroleukemia cells. Evidence for a protease which requires ATP hydrolysis but not ubiquitin.

1985 • 70 citations

Lysosomal degradation of ribonuclease A and ribonuclease S-protein microinjected into the cytosol of human fibroblasts.

1985 • 65 citations

Role for the Adenosine Triphosphate-Dependent Proteolytic Pathway in Reticulocyte Maturation

1982 • 59 citations

Role of lysosomes in protein turnover: Catch‐up proteolysis after release from NH₄Cl inhibition

1980 • 39 citations

ATP-dependent degradation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in permeabilized cells.

1987 • 37 citations

Effects of ATP, vanadate, and molybdate on cathepsin D-catalyzed proteolysis.

1985 • 36 citations

Protein synthesis and degradation in growth regulation in rat embryo fibroblasts: Role of fast‐turnover and slow‐turnover protein

1980 • 36 citations

Intracellular protein degradation in serum-deprived human fibroblasts

1986 • 29 citations

The regulation of proteolysis in normal fibroblasts as they approach confluence. Evidence for the participation of the lysosomal system

1982 • 28 citations

A particle-associated ATP-dependent proteolytic activity in erythroleukemia cells.

1985 • 24 citations

Proteolysis in isolated autophagic vacuoles from rat liver

1982 • 22 citations

Cytochrome P-450 linked mixed function oxidase turnover of microsomal components and effects of inducers on the turnover phospholipids, proteins and specific enzymes

1980 • 21 citations

The suppression of endogenous protein degradation by fractions of foetal calf serum: Dialysed serum is less able to suppress degradation in aged cells

1986 • 10 citations