Ryanodine Receptor Adaptation: Control Mechanism of Ca ²⁺ -Induced Ca ²⁺ Release in Heart

Single-Channel Recording

1995 • 2,565 citations

Primary structure and expression from complementary DNA of skeletal muscle ryanodine receptor

1989 • 1,132 citations

Primary structure and functional expression of the inositol 1,4,5-trisphosphate-binding protein P400

1989 • 1,039 citations

Purification and reconstitution of the calcium release channel from skeletal muscle

1988 • 928 citations

Time and calcium dependence of activation and inactivation of calcium-induced release of calcium from the sarcoplasmic reticulum of a skinned canine cardiac Purkinje cell.

1985 • 904 citations

Calcium as a Coagonist of Inositol 1,4,5-Trisphosphate-Induced Calcium Release

1991 • 843 citations

‘Quanta’ Ca²⁺ release and the control of Ca²⁺ entry by inositol phosphates ‐ a possible mechanism

1990 • 743 citations

Theory of excitation-contraction coupling in cardiac muscle

1992 • 651 citations

Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist

1980 • 608 citations

Ryanodine modifies conductance and gating behavior of single Ca2+ release channel

1987 • 548 citations

Purified ryanodine receptor from rabbit skeletal muscle is the calcium-release channel of sarcoplasmic reticulum.

1988 • 475 citations

Single channel measurements of the calcium release channel from skeletal muscle sarcoplasmic reticulum. Activation by Ca2+ and ATP and modulation by Mg2+.

1986 • 403 citations

Effect of Membrane Potential Changes on the Calcium Transient in Single Rat Cardiac Muscle Cells

1987 • 353 citations

Hormone-evoked calcium release from intracellular stores is a quantal process

1989 • 312 citations

Photolabile chelators for the rapid photorelease of divalent cations.

1988 • 295 citations

Ca2+ release induced by inositol 1,4,5-trisphosphate is a steady-state phenomenon controlled by luminal Ca2+ in permeabilized cells

1992 • 265 citations

Role of Ca2+ channel in cardiac excitation‐contraction coupling in the rat: evidence from Ca2+ transients and contraction.

1991 • 234 citations

Flux of Ca2+ across the sarcoplasmic reticulum of guinea‐pig cardiac cells during excitation‐contraction coupling.

1991 • 209 citations

Localized All-or-None Calcium Liberation by Inositol Trisphosphate

1990 • 205 citations

Voltage-Independent Calcium Release in Heart Muscle

1990 • 183 citations

Inactivation of calcium release from the sarcoplasmic reticulum in frog skeletal muscle.

1988 • 183 citations

Transient calcium release induced by successive increments of inositol 1,4,5-trisphosphate.

1990 • 180 citations

Quantal calcium release by purified reconstituted inositol 1,4,5-trisphosphate receptors

1992 • 136 citations

Use of chlorotetracycline fluorescence to demonstrate Ca2+-induced release of Ca2+ from the sarcoplasmic reticulum of skinned cardiac cells

1979 • 127 citations

Phosphate burst in permeable muscle fibers of the rabbit

1986 • 116 citations

Evidence for a Ca2+ channel within the ryanodine receptor complex from cardiac sarcoplasmic reticulum

1988 • 114 citations

The size of inositol 1,4,5-trisphosphate-sensitive Ca2+ stores depends on inositol 1,4,5-trisphosphate concentration

1990 • 114 citations

Ca2(+)-induced Ca2+ release as examined by photolysis of caged Ca2+ in single ventricular myocytes

1990 • 79 citations

Nucleotide specificity of cardiac sarcoplasmic reticulum. GTP-induced calcium accumulation and GTPase activity.

1985 • 31 citations

Antibodies as probes for ligand gating of single sarcoplasmic reticulum Ca2+-release channels

1991 • 27 citations

Effects of perchlorate on excitation‐contraction coupling in frog and crayfish skeletal muscle.

1992 • 19 citations

Dynamic control of inositol 1,4,5-trisphosphate-induced Ca2+ release: a theoretical explanation for the quantal release of Ca2+.

1992 • 15 citations