Single acetylcholine-activated channels show burst-kinetics in presence of desensitizing concentrations of agonist

Single-channel currents recorded from membrane of denervated frog muscle fibres

1976 • 2,456 citations

Voltage clamp analysis of acetylcholine produced end‐plate current fluctuations at frog neuromuscular junction

1973 • 992 citations

The statistical nature of the acetylcholine potential and its molecular components

1972 • 960 citations

Local anaesthetics transiently block currents through single acetylcholine‐receptor channels.

1978 • 864 citations

The extracellular patch clamp: A method for resolving currents through individual open channels in biological membranes

1978 • 511 citations

Decamethonium both opens and blocks endplate channels.

1978 • 168 citations

Rates and equilibria at the acetylcholine receptor of Electrophorus electroplaques: a study of neurally evoked postsynaptic currents and of voltage-jump relaxations.

1977 • 145 citations

A study of desensitization using voltage clamp

1975 • 108 citations

The effect of temperature on desensitization kinetics at the post‐synaptic membrane of the frog muscle fibre.

1975 • 95 citations

ADVANCES IN PHARMACOLOGY AND THERAPEUTICS

1979 • 85 citations

Desensitization and recovery at the frog neuromuscular junction.

1977 • 54 citations