Increased gene-specific repair of cisplatin interstrand cross-links in cisplatin-resistant human ovarian cancer cell lines.

DNA repair in an active gene: Removal of pyrimidine dimers from the DHFR gene of CHO cells is much more efficient than in the genome overall

1985 • 1,233 citations

Adducts of the antitumor drug cis-diamminedichloroplatinum(II) with DNA: formation, identification, and quantitation

1985 • 994 citations

Cisplatin

1984 • 942 citations

Structural aspects of platinum anticancer drug interactions with DNA

1987 • 927 citations

DNA repair: a laboratory manual of research procedures

1981 • 818 citations

Overexpression of Metallothionein Confers Resistance to Anticancer Drugs

1988 • 600 citations

Cancer Chemotherapy: Principles and Practice

1990 • 568 citations

Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion

1985 • 545 citations

Cellular pharmacology of cisplatin: perspectives on mechanisms of acquired resistance.

1990 • 393 citations

Enhanced DNA repair as a mechanism of resistance to cis-diamminedichloroplatinum(II)

1988 • 314 citations

Acquired cisplatin resistance in human ovarian cancer cells is associated with enhanced repair of cisplatin-DNA lesions and reduced drug accumulation.

1991 • 288 citations

Characterization of a human squamous carcinoma cell line resistant to cis-diamminedichloroplatinum(II).

1987 • 288 citations

Increased DNA repair as a mechanism of acquired resistance to cis-diamminedichloroplatinum (II) in human ovarian cancer cell lines.

1988 • 281 citations

DNA cross-linking as an indicator of sensitivity and resistance of mouse L1210 leukemia to cis-diamminedichloroplatinum(II) and L-phenylalanine mustard.

1981 • 213 citations

Survival of UV-irradiated mammalian cells correlates with efficient DNA repair in an essential gene.

1986 • 196 citations

Differential potentiation of alkylating and platinating agent cytotoxicity in human ovarian carcinoma cells by glutathione depletion.

1985 • 195 citations

Gene specific DNA repair

1991 • 181 citations

Gene-specific formation and repair of cisplatin intrastrand adducts and interstrand cross-links in Chinese hamster ovary cells.

1991 • 157 citations

Processing of psoralen adducts in an active human gene: Repair and replication of DNA containing monoadducts and interstrand cross-links

1987 • 151 citations

Increased removal of DNA-bound platinum in a human ovarian cancer cell line resistant to cis-diamminedichloroplatinum(II).

1990 • 98 citations

Elevated expression of thymidylate synthase cycle genes in cisplatin-resistant human ovarian carcinoma A2780 cells.

1988 • 98 citations

Quenching of DNA:platinum(II) monoadducts as a possible mechanism of resistance to cis-diamminedichloroplatinum(II) in L1210 cells.

1983 • 96 citations

DNA Repair and Its Pathogenetic Implications

1990 • 69 citations

General method for quantifying base adducts in specific mammalian genes.

1988 • 63 citations

Comparative Pharmacokinetics of DNA Lesion Formation and Removal Following Treatment of L1210 Cells with Nitrogen Mustards

1990 • 60 citations

Quantitative aspects of the formation and loss of DNA interstrand crosslinks in Chinese hamster cells following treatment with cis-diamminedichloroplatinum(II) (cisplatin) I. Proportion of DNA-platinum reactions involved in DNA crosslinking

1981 • 58 citations

DNA repair in the c-myc proto-oncogene locus: possible involvement in susceptibility or resistance to plasmacytoma induction in BALB/c mice.

1991 • 35 citations

Human repair gene restores normal pattern of preferential DNA repair in repair defective CHO cells

1988 • 28 citations

Induction of a mutant phenotype in human repair proficient cells after overexpression of a mutated human DNA repair gene

1991 • 18 citations

Gene-specific repair of DNA damage induced by UV irradiation and cancer chemotherapeutics.

1991 • 16 citations

Ovary and fallopian tubes

2008 • 2 citations