Essential Role for Nitric Oxide in Neurogenic Inflammation in Rat Cutaneous Microcirculation

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

Localization of nitric oxide synthase indicating a neural role for nitric oxide

1990 • 2,996 citations

Calcitonin gene-related peptide is a potent vasodilator

1985 • 2,050 citations

Role of endothelium-derived nitric oxide in the regulation of blood pressure.

1989 • 1,837 citations

Local effector functions of capsaicin-sensitive sensory nerve endings: Involvement of tachykinins, calcitonin gene-related peptide and other neuropeptides

1988 • 1,673 citations

Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation

1979 • 1,199 citations

Nitric oxide as an inhibitory non-adrenergic non-cholinergic neurotransmitter

1990 • 1,012 citations

<scp>l</scp>‐N^G‐nitro arginine (<scp>l</scp>‐NOARG), a novel, <scp>l</scp>‐arginine‐reversible inhibitor of endothelium‐dependent vasodilatation in vitro

1990 • 769 citations

Biological Roles of Nitric Oxide

1992 • 731 citations

Modulation of acute inflammation by endogenous nitric oxide

1992 • 543 citations

Characterization of the novel nitric oxide synthase inhibitor 7‐nitro indazole and related indazoles: antinociceptive and cardiovascular effects

1993 • 470 citations

Sensory neuron-specific actions of capsaicin: mechanisms and applications

1990 • 452 citations

Inflammatory oedema induced by synergism between calcitonin gene‐related peptide (CGRP) and mediators of increased vascular permeability

1985 • 445 citations

Pharmacological properties of a potent and selective nonpeptide substance P antagonist.

1991 • 429 citations

7‐Nitro indazole, an inhibitor of nitric oxide synthase, exhibits anti‐nociceptive activity in the mouse without increasing blood pressure

1993 • 426 citations

Nitric oxide is the endogenous neurotransmitter of bronchodilator nerves in humans

1992 • 396 citations

Modulation of the vasodepressor actions of acetylcholine, bradykinin, substance P and endothelin in the rat by a specific inhibitor of nitric oxide formation

1989 • 270 citations

Modulation of neurotransmission in airways

1992 • 247 citations

Calcitonin gene-related peptide mediates nitroglycerin and sodium nitroprusside-induced vasodilation in feline cerebral arterioles.

1992 • 238 citations

<scp>l</scp>‐N^G‐nitro arginine inhibits non‐adrenergic, non‐cholinergic relaxations of guinea‐pig isolated tracheal smooth muscle

1990 • 230 citations

Evidence that endogenous nitric oxide modulates oedema formation induced by substance P

1990 • 201 citations

<scp>l</scp>‐N^G‐monomethyl arginine and <scp>l</scp>‐N^G‐nitro arginine inhibit non‐adrenergic, non‐cholinergic relaxation of the mouse anococcygeus muscle

1990 • 201 citations

Modulation of neurogenic inflammation: novel approaches to inflammatory disease

1990 • 197 citations

The non‐peptide tachykinin antagonist, CP‐96,345, is a potent inhibitor of neurogenic inflammation

1992 • 185 citations

Interactions between the tachykinins and calcitonin gene‐related peptide lead to the modulation of oedema formation and blood flow in rat skin

1989 • 151 citations

Nitric oxide may act as a messenger between dorsal root ganglion neurones and their satellite cells

1992 • 136 citations

Mechanism of action of capsaicin-like molecules on sensory neurons

1992 • 114 citations

Neuropharmacological mechanisms of capsaicin and related substances

1992 • 114 citations

Effect of a calcitonin gene‐related peptide antagonist (CGRP_8–37) on skin vasodilatation and oedema induced by stimulation of the rat saphenous nerve

1993 • 107 citations

Modulation of rat mast cell reactivity by IL-1 beta. Divergent effects on nitric oxide and platelet-activating factor release.

1993 • 95 citations

Nitric oxide‐dependent release of vasodilator quantities of calcitonin gene‐related peptide from capsaicin‐sensitive nerves in rabbit skin

1994 • 83 citations

Neurogenic influences in arthritis.

1990 • 80 citations

Relative involvement of substance P and CGRP mechanisms in antidromic vasodilation in the rat skin

1992 • 79 citations

Participation of nitric oxide in the mustard oil-induced neurogenic i inflammation of the rat paw skin

1993 • 71 citations

Nitric oxide and sensory nerves are involved in the vasodilator response to acetylcholine but not calcitonin gene‐related peptide in rat skin micro vasculature

1992 • 70 citations

Tachykinin antagonists and capsaicin‐induced contraction of the rat isolated urinary bladder: evidence for tachykinin‐mediated cotransmission

1991 • 63 citations

Activation of Guanylate Cyclase by Bradykinin in Rat Sensory Neurones Is Mediated by Calcium Influx: Possible Role of the Increase in Cyclic GMP

1989 • 62 citations

Capsaicin‐Induced Ion Fluxes Increase Cyclic GMP but Not Cyclic AMP Levels in Rat Sensory Neurones in Culture

1989 • 60 citations

Distribution of NADPH-diaphorase-positive nerves in the uterine cervix and neurons in dorsal root and paracervical ganglia of the female rat

1992 • 60 citations

CGRP immunoreactivity and NADPH-diaphorase in afferent nerves of the rat penis

1992 • 52 citations

Arthritis and the nervous system

1989 • 42 citations

Responses to endothelins in the rat cutaneous microvasculature: a modulatory role of locally‐produced nitric oxide

1992 • 34 citations

Migraine: a research field matured for the basic neurosciences

1991 • 25 citations

Failure of L‐nitroarginine, a nitric oxide synthase inhibitor, to affect hypotension and plasma protein extravasation produced by tachykinin NK‐1 receptor activation in rats

1993 • 17 citations

Airway inflammation induced by xanthine/xanthine oxidase in guinea pigs

1993 • 11 citations