Pharmacological properties of a potent and selective nonpeptide substance P antagonist.

A simplified method of evaluating dose-effect experiments.

1948 • 7,047 citations

SOME QUANTITATIVE USES OF DRUG ANTAGONISTS

1959 • 3,948 citations

An unidentified depressor substance in certain tissue extracts

1931 • 1,565 citations

Substance P as neurogenic mediator of antidromic vasodilation and neurogenic plasma extravasation

1979 • 1,199 citations

A Potent Nonpeptide Antagonist of the Substance P (NK ₁ ) Receptor

1991 • 875 citations

Formalin test in mice, a useful technique for evaluating mild analgesics

1985 • 818 citations

cDNA eloping of bovine substance-K receptor through oocyte expression system

1987 • 748 citations

Substance P as a Transmitter Candidate

1980 • 522 citations

A Method for Evaluating both Non-Narcotic and Narcotic Analgesics

1957 • 493 citations

Molecular characterization of a functional cDNA for rat substance P receptor

1989 • 463 citations

Specific stimulation of human T lymphocytes by substance P.

1983 • 461 citations

Vascular protein leakage in various tissues induced by substance P, capsaicin, bradykinin, serotonin, histamine and by antigen challenge

1983 • 429 citations

New selective agonists for neurokinin receptors: pharmacological tools for receptor characterization

1988 • 360 citations

Highly selective agonists for substance P receptor subtypes.

1986 • 316 citations

Cloning and expression of a rat neuromedin K receptor cDNA.

1990 • 308 citations

Multiple tachykinin binding sites in peripheral tissues and in brain

1986 • 276 citations

Stereospecific receptors for substance P on cultured human IM-9 lymphoblasts.

1984 • 173 citations

Effects of peptides and non-peptides on isolated arterial smooth muscles: Role of endothelium

1985 • 173 citations

Species differences in affinities of non-peptide antagonists for substance p receptors

1991 • 163 citations

The rat isolated portal vein: a preparation sensitive to neurokinins, particularly neurokinin B

1987 • 144 citations

Substance P.

1983 • 138 citations

3h-substance P binding to salivary gland membranes. Regulation by guanyl nucleotides and divalent cations.

1983 • 116 citations

Substance P

1982 • 99 citations

Pharmacological analysis of [³H]‐senktide binding to NK₃ tachykinin receptors in guinea‐pig ileum longitudinal muscle‐myenteric plexus and cerebral cortex membranes

1990 • 93 citations

Analysis of tachykinin binding site interactions using constrained analogues of tachykinins

1988 • 92 citations

The pharmacological profile of a substance P (SP) antagonist. Evidence for the existence of subpopulations of SP receptors

1983 • 91 citations

[pGlu6, Pro9]SP6-11, a selective agonist for the substance P P-receptor subtype

1986 • 85 citations

Pharmacological characterization of four related substance P antagonist

1982 • 71 citations

3H-neurokinin A labels a specific tachykinin-binding site in the rat duodenal smooth muscle.

1987 • 67 citations

Effects of tachykinins and selective tachykinin receptor agonists on vascular permeability in the rat lower urinary tract: evidence for the involvement of NK‐1 receptors

1989 • 37 citations

Tissue fractionation in rat brain, kidney and liver

1975 • 21 citations