Identification of allelic losses in benign, borderline, and invasive epithelial ovarian tumors and correlation with clinical outcome

A Cell Cycle Regulator Potentially Involved in Genesis of Many Tumor Types

1994 • 2,821 citations

DPC4 , A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1

1996 • 2,320 citations

BRCA1 Mutations in Primary Breast and Ovarian Carcinomas

1994 • 1,205 citations

Histological Typing of Ovarian Tumours

1999 • 668 citations

SAMPLE PREPARATION FROM PARAFFIN-EMBEDDED TISSUES

1990 • 565 citations

Mad-related genes in the human

1996 • 308 citations

Studies on Bilirubin in Amniotic Fluid: With Special Reference to Liver Function Tests

1971 • 271 citations

Histological Typing of Ovarian Tumours

1975 • 263 citations

Allelotype of human ovarian cancer.

1991 • 257 citations

Human epithelial ovarian cancer allelotype.

1993 • 241 citations

Mutation of K-ras protooncogene in human ovarian epithelial tumors of borderline malignancy.

1993 • 238 citations

p53 and Ki-ras gene mutations in epithelial ovarian neoplasms.

1993 • 216 citations

Ovarian epithelial tumors of borderline malignancy: A clinical and pathologic study of 109 cases

1986 • 198 citations

Frequent allelic losses and mutations of the p53 gene in human ovarian cancer.

1991 • 194 citations

Evidence of cumulative gene losses with progression of premalignant epithelial lesions to carcinoma of the bronchus

1996 • 182 citations

p53 mutation is a common genetic event in ovarian carcinoma.

1993 • 177 citations

Allelic loss of chromosome 1 and additional chromosome 17 material are both unfavourable prognostic markers in neuroblastoma

1995 • 174 citations

Mutation and overexpression of p53 in early-stage epithelial ovarian cancer.

1993 • 168 citations

Overrepresentation of 3q and 8q material and loss of 18q material are recurrent findings in advanced human ovarian cancer

1996 • 130 citations

Frequent loss of heterozygosity on chromosome 6 in human ovarian carcinoma

1993 • 126 citations

Allelic Loss at Chromosomes 3p, 8p, 13q, and l7p Associated With Poor Prognosis in Head and Neck Cancer

1994 • 126 citations

Accumulation of allelic loss on arms of chromosomes 13q, 16q and 17p in the advanced stages of human hepatocellular carcinoma

1992 • 113 citations

Allelic deletion on chromosome 17p13.3 in early ovarian cancer.

1996 • 112 citations

Definition and refinement of a region of loss of heterozygosity at 11q23.3-q24.3 in epithelial ovarian cancer associated with poor prognosis.

1996 • 108 citations

Epithelial ovarian tumors of borderline malignancy

1990 • 106 citations

Comparison of loss of heterozygosity patterns in invasive low-grade and high-grade epithelial ovarian carcinomas.

1993 • 97 citations

Characterization of chromosome 9 in human ovarian neoplasia identifies frequent genetic imbalance on 9q and rare alterations involving 9p, including CDKN2.

1995 • 95 citations

Overexpression of the p53 protein and allele loss at 17p13 in ovarian carcinoma

1992 • 94 citations

Microsatellite instability in adenocarcinomas of the upper gastrointestinal tract. Relation to clinicopathological data and family history.

1995 • 89 citations

Polymerase chain reaction allelotyping of human ovarian cancer

1994 • 87 citations

Allelic loss on chromosome 17 in human ovarian cancer

1993 • 84 citations

Early loss of heterozygosity on 17q in ovarian cancer. The Abe Ovarian Cancer Genetics Group.

1992 • 84 citations

Allele loss on chromosome arm 6q and fine mapping of the region at 6q27 in epithelial ovarian cancer

1996 • 83 citations

Genetic alterations distinguish different types of ovarian tumors

1995 • 78 citations

Genetic Disparity Between Morphologically Benign Cysts Contiguous to Ovarian Carcinomas and Solitary Cystadenomas

1995 • 77 citations

Loss of heterozygosity on chromosome 13 is common only in the biologically more aggressive subtypes of ovarian epithelial tumors and is associated with normal retinoblastoma gene expression.

1994 • 77 citations

Assessment of p53 expression in nasopharyngeal carcinoma*1

1995 • 77 citations

p53 mutations in ovarian tumors, detected by temperature‐gradient gel electrophoresis, direct sequencing and immunohistochemistry

1995 • 76 citations

Genetic studies of 457 breast cancers. Clinicopathologic parameters compared with genetic alterations

1994 • 69 citations

p53 Gene Mutation in Human Borderline Epithelial Ovarian Tumors

1994 • 65 citations

p53 gene analysis of ovarian borderline tumors and stage I carcinomas*1

1995 • 65 citations

A P1-based physical map of the region from D17S776 to D17S78 containing the breast cancer susceptibility gene BRCA1

1994 • 61 citations

Alteration of the p53 Tumor Suppressor Gene Occurs Independently of K‐ras Activation and More Frequently in Serous Adenocarcinomas than in Other Common Epithelial Tumors of the Human Ovary

1994 • 58 citations

The molecular basis of ovarian cancer

1995 • 57 citations

Genetic alterations on chromosome 17 distinguish different types of epithelial ovarian tumors*1

1995 • 54 citations

[Ovarian epithelial tumors of borderline malignancy].

1992 • 53 citations

p53 Expression, mutation, and allelic deletion in ovarian cancer

1994 • 48 citations

Loss of heterozygosity on chromosome 5 in sporadic ovarian carcinoma is a late event and is not associated with mutations in APC at 5q21-22

1994 • 36 citations

DNA cytophotometry and prognosis in ovarian tumors of borderline malignancy. A clinicomorphologic study of 80 cases

1992 • 35 citations

Detailed deletion mapping of chromosome 6q in borderline epithelial ovarian tumors.

1995 • 32 citations

p53 Mutation in epithelial ovarian carcinoma and borderline ovarian tumor

1995 • 28 citations

Dinucleotide repeat polymorphism at the D18S34 locus

1990 • 27 citations

Dinucleotide repeat polymorphism at the D5S134 locus linked to the adenomatous polyposis coli (APC) gene

1992 • 21 citations

p53 MUTATION, ALLELE LOSS ON CHROMOSOME 17p, AND DNA CONTENT IN OVARIAN CARCINOMA

1996 • 19 citations

Dinucleotide repeat polymorphism at the D9S43 locus

1990 • 17 citations

Thirteen dinucleotide repeat polymorphisms on chromosome 6

1993 • 14 citations

CA-repeat polymorphism at the D22S430 locus adjacent to NF2

1993 • 14 citations

Taql and Rsal polymorphisms in the H19 gene (D11S813E)

1993 • 9 citations

Dinucleotide repeat polymorphism at the NCAM locus

1994 • 9 citations

Use of non-radioactive detection in SSCP, direct DNA sequencing and LOH analysis

1996 • 7 citations

Dinucleotide repeat polymorphism at the D9S126 locus (9p21)

1993 • 7 citations

Dinucleotide repeat polymorphism at the D22S351 locus

1993 • 7 citations

Trinucleotide repeat polymorphism at the D5S373 locus

1993 • 4 citations

An A to G polymorphism in the SHBG gene

1994 • 3 citations

Two dinucleotide repeat polymorphisms at 17p13

1994 • 3 citations

Dinucleotide repeat polymorphism at the D2S71 locus

1990 • 3 citations