Loss of heterozygosity on chromosome 5 in sporadic ovarian carcinoma is a late event and is not associated with mutations in APC at 5q21-22

Identification and characterization of the familial adenomatous polyposis coli gene

1991 • 2,806 citations

Identification of FAP Locus Genes from Chromosome 5q21

1991 • 2,358 citations

APC mutations occur early during colorectal tumorigenesis

1992 • 1,901 citations

Mutations of Chromosome 5q21 Genes in FAP and Colorectal Cancer Patients

1991 • 1,890 citations

Direct solid phase sequencing of genomic and plasmid DNA using magnetic beads as solid support

1989 • 747 citations

Chromosome 5 allele loss in human colorectal carcinomas

1987 • 566 citations

Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients.

1992 • 562 citations

Catalog of Chromosome Aberrations in Cancer

1992 • 405 citations

Identification of five different insulin-like growth factor binding proteins (IGFBPs) from adult rat serum and molecular cloning of a novel IGFBP-5 in rat and human

1991 • 313 citations

Principles and Practice of Medical Genetics.

1991 • 260 citations

Molecular analysis of APC mutations in familial adenomatous polyposis and sporadic colon carcinomas

1992 • 257 citations

Allelotype of human ovarian cancer.

1991 • 257 citations

Human epithelial ovarian cancer allelotype.

1993 • 241 citations

Loss of heterozygosity involving the APC and MCC genetic loci occurs in the majority of human esophageal cancers.

1992 • 224 citations

The APC gene, responsible for familial adenomatous polyposis, is mutated in human gastric cancer.

1992 • 223 citations

Frequent somatic mutations of the APC gene in human pancreatic cancer.

1992 • 213 citations

Polymorphism in a second ABC transporter gene located within the class II region of the human major histocompatibility complex.

1992 • 190 citations

Frequent loss of heterozygosity on chromosomes 6q, 11, and 17 in human ovarian carcinomas.

1990 • 189 citations

Report of the committee on chromosome and gene loss in human neoplasia

1991 • 158 citations

Clonal Origin of Epithelial Ovarian Carcinoma: Analysis by Loss of Heterozygosity, p53 Mutation, and X-Chromosome Inactivation

1992 • 157 citations

Common regions of deletion on chromosomes 5q, 6q, and 10q in renal cell carcinoma.

1991 • 154 citations

Loss of heterozygosity on chromosomal segments 3p, 6q and 11p in human ovarian carcinomas.

1990 • 144 citations

Mutational analysis of patients with adenomatous polyposis: identical inactivating mutations in unrelated individuals.

1993 • 139 citations

A CA repeat 30–70 Kb downstream from the adenomatous polyposis coli (APC) gene

1992 • 136 citations

Germ-line mutations in the first 14 exons of the adenomatous polyposis coli (APC) gene.

1993 • 129 citations

Screening for germ-line mutations in familial adenomatous polyposis patients: 61 new patients and a summary of 150 unrelated patients

1992 • 115 citations

Polymorphic sites within the MCC and APC loci reveal very frequent loss of heterozygosity in human small cell lung cancer.

1992 • 106 citations

Allelic loss in ovarian cancer

1993 • 100 citations

A CA repeat 30 – 70 KB downstream from the adenomatous polyposis coli (APC) gene

1991 • 96 citations

Very frequent loss of heterozygosity throughout chromosome 17 in sporadic ovarian carcinoma

1993 • 83 citations

Nonhomologous chromatid exchange in hereditary and sporadic renal cell carcinomas.

1991 • 82 citations

A chromosome study of three ovarian tumors

1987 • 76 citations

MCC, a candidate familial polyposis gene in 5q.21, shows frequent allele loss in colorectal and lung cancer.

1991 • 64 citations

Loss of both CSF1R (FMS) alleles in patients with myelodysplasia and a chromosome 5 deletion.

1991 • 58 citations

Consistent occurrence of a 19p+ marker chromosome and loss of 11p material in ovarian seropapillary cystadenocarcinomas

1989 • 58 citations

Two Mspl polymorphisms within the APC gene

1992 • 18 citations

ONCOLOGY

1993 • 4 citations

OVER-EXPRESSION OF CELLULAR ONCOGENES IN CYSTADENOCARCINOMAS OF THE OVARY

1992 • 2 citations