Genetic alterations distinguish different types of ovarian tumors

A Strong Candidate for the Breast and Ovarian Cancer Susceptibility Gene BRCA1

1994 • 5,994 citations

Molecular determinants of dysplasia in colorectal lesions.

1994 • 506 citations

p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3

1995 • 426 citations

Somatic mutations in the BRCA1 gene in sporadic ovarian tumours

1995 • 377 citations

A dot-blot screening procedure for mutated ras oncogenes using synthetic oligodeoxynucleotides

1986 • 351 citations

Mutation of K-ras protooncogene in human ovarian epithelial tumors of borderline malignancy.

1993 • 238 citations

Detailed deletion mapping of chromosome 17q in ovarian and breast cancers: 2-cM region on 17q21.3 often and commonly deleted in tumors.

1993 • 192 citations

Mutation of K-ras protooncogene is associated with histological subtypes in human mucinous ovarian tumors.

1994 • 145 citations

A deletion unit on chromosome 17q in epithelial ovarian tumors distal to the familial breast/ovarian cancer locus.

1993 • 105 citations

All in the (cancer) family

1993 • 93 citations

Polymerase chain reaction allelotyping of human ovarian cancer

1994 • 87 citations

Allelic loss on chromosome 17 in human ovarian cancer

1993 • 84 citations

Early loss of heterozygosity on 17q in ovarian cancer. The Abe Ovarian Cancer Genetics Group.

1992 • 84 citations

Very frequent loss of heterozygosity throughout chromosome 17 in sporadic ovarian carcinoma

1993 • 83 citations

A common region of deletion on chromosome 17q in both sporadic and familial epithelial ovarian tumors distal to BRCA1.

1994 • 82 citations

Loss of heterozygosity and genomic instability in synchronous endometrioid tumors of the ovary and endometrium

1995 • 71 citations

Genetic alterations on chromosome 17 distinguish different types of epithelial ovarian tumors*1

1995 • 54 citations

Whole chromosome 17 loss in ovarian cancer

1993 • 31 citations

Hypermethylation at a chromosome 17 ?Hot spot? is a common event in ovarian cancer*1

1995 • 28 citations