Review : Apoptosis and Spinal Cord Injury

Apoptosis: A Basic Biological Phenomenon with Wideranging Implications in Tissue Kinetics

1972 • 15,349 citations

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Apoptosis by Death Factor

1997 • 5,038 citations

Programmed Cell Death in Animal Development

1997 • 2,690 citations

Mechanisms and Genes of Cellular Suicide

1995 • 2,514 citations

The proto-oncogene Bcl-2 and its role in regulating apoptosis

1997 • 1,768 citations

Two methods for selective silver impregnation of degenerating axons and their synaptic endings in the central nervous system

1967 • 1,751 citations

Programmed Cell Death and the Control of Cell Survival: Lessons from the Nervous System

1993 • 1,470 citations

Graded Histological and Locomotor Outcomes after Spinal Cord Contusion Using the NYU Weight-Drop Device versus Transection

1996 • 1,440 citations

Massive Cell Death of Immature Hematopoietic Cells and Neurons in Bcl-x-Deficient Mice

1995 • 1,167 citations

Apoptosis and delayed degeneration after spinal cord injury in rats and monkeys

1997 • 1,147 citations

Altered neuronal and microglial responses to excitotoxic and ischemic brain injury in mice lacking TNF receptors

1996 • 947 citations

Neuronal and Glial Apoptosis after Traumatic Spinal Cord Injury

1997 • 901 citations

Cellular inflammatory response after spinal cord injury in sprague-dawley and lewis rats

1997 • 892 citations

Isolation, Characterization, and use of Stem Cells from the CNS

1995 • 819 citations

Axotomy results in delayed death and apoptosis of retinal ganglion cells in adult rats

1994 • 817 citations

A Monitored Contusion Model of Spinal Cord Injury in the Rat

1992 • 736 citations

Multiple extracellular signals are required for long-term oligodendrocyte survival

1993 • 707 citations

Ischemia-induced neuronal apoptosis

1996 • 600 citations

Observations on the pathology of human spinal cord injury. A review and classification of 22 new cases with details from a case of chronic cord compression with extensive focal demyelination.

1993 • 582 citations

Temporal analysis of events associated with programmed cell death (apoptosis) of sympathetic neurons deprived of nerve growth factor.

1993 • 535 citations

Secondary Cell Death and the Inflammatory Reaction After Dorsal Hemisection of the Rat Spinal Cord

1994 • 531 citations

Evidence of apoptotic cell death after experimental traumatic brain injury in the rat.

1995 • 517 citations

Neuregulins and Their Receptors: A Versatile Signaling Module in Organogenesis and Oncogenesis

1997 • 471 citations

Rapid, widespread, and longlasting induction of nestin contributes to the generation of glial scar tissue after CNS injury.

1995 • 471 citations

MASCIS Evaluation of Open Field Locomotor Scores: Effects of Experience and Teamwork on Reliability

1996 • 441 citations

Endogenous Repair after Spinal Cord Contusion Injuries in the Rat

1997 • 398 citations

Apoptosis of microglia and oligodendrocytes after spinal cord contusion in rats

1997 • 371 citations

The effects of methylprednisolone and the ganglioside GM1 on acute spinal cord injury in rats

1994 • 330 citations

Does oligodendrocyte survival depend on axons?

1993 • 291 citations

Interferon-gamma-induced oligodendrocyte cell death: implications for the pathogenesis of multiple sclerosis.

1995 • 283 citations

Spinal cord contusion in the rat: Morphometric analyses of alterations in the spinal cord☆

1985 • 274 citations

Morphometric analysis of experimental spinal cord injury in the cat: The relation of injury intensity to survival of myelinated axons

1986 • 268 citations

Apoptosis and Expression of Bcl-2 after Compression Trauma to Rat Spinal Cord

1996 • 259 citations

In situ demonstration of mature oligodendrocytes and their processes: An immunocytochemical study with a new monoclonal antibody, Rip

1989 • 252 citations

Interferon-γ-Induced Oligodendrocyte Cell Death: Implications for the Pathogenesis of Multiple Sclerosis

1995 • 249 citations

Spinal Cord Injury Produced by Consistent Mechanical Displacement of the Cord in Rats: Behavioral and Histologic Analysis

1992 • 247 citations

Expression of the APC tumor suppressor protein in oligodendroglia

1996 • 235 citations

A behavioral and anatomical analysis of spinal cord injury produced by a feedback-controlled impaction device

1987 • 231 citations

Modeling of Acute Spinal Cord Injury in the Rat: Neuroprotection and Enhanced Recovery with Methylprednisolone, U-74006F and YM-14673

1994 • 186 citations

Differential susceptibility of human CNS-derived cell populations to TNF-dependent and independent immune-mediated injury

1995 • 180 citations

Apoptosis Overview Emphasizing the Role of Oxidative Stress, DNA Damage and Signal- Transduction Pathways

1995 • 175 citations

Axonal Neuregulin Signals Cells of the Oligodendrocyte Lineage through Activation of HER4 and Schwann Cells through HER2 and HER3

1997 • 172 citations

An electron-microscopic analysis of axonal alterations following blunt contusion of the spinal cord of the rhesus monkey (Macaca mulatta)

1978 • 171 citations

Neuronal Apoptosis: Current Understanding of Molecular Mechanisms and Potential Role in Ischemic Brain Injury

1995 • 168 citations

Amelioration of Functional Deficits from Spinal Cord Trauma with Systemically Administered NBQX, an Antagonist of Non-N-methyl-D-aspartate receptors

1996 • 152 citations

Neutrophil inhibitory factor is neuroprotective after focal Ischemia in rats

1995 • 150 citations

Increased Expression of IL-1β Converting Enzyme in Hippocampus after Ischemia: Selective Localization in Microglia

1996 • 149 citations

A neuroanatomical analysis of spinal cord injury in the rhesus monkey (Macaca mulatta)

1976 • 123 citations

MR-pathologic comparisons of wallerian degeneration in spinal cord injury.

1995 • 115 citations

An Electromechanical Spinal Injury Technique with Dynamic Sensitivity

1992 • 114 citations

Genetic influences on cellular reactions to spinal cord injury: A wound-healing response present in normal mice is impaired in mice carrying a mutation (WldS) that causes delayed Wallerian degeneration

1996 • 92 citations

DNA Damage and Repair in Central Nervous System Injury

1996 • 88 citations

Induction of apoptosis by p75 neurotrophin receptor in human neuroblastoma cells

1997 • 75 citations

Central glial and neuronal populations display differential sensitivity to ceramide-dependent cell death

1996 • 69 citations

An endogenous 55 kDa TNF receptor mediates cell death in a neural cell line

1996 • 62 citations

Lack of Effect of Postinjury Treatment with Methylprednisolone or Tirilazad Mesylate on the Increase in Eicosanoid Levels in the Acutely Injured Cat Spinal Cord

1995 • 40 citations

REVIEW ■ : Keeping Neurons Alive: The Molecular Control of Apoptosis (Part I

1996 • 39 citations

Experimental Spinal Cord Injury

1988 • 17 citations

Spinal Cord Repair: Progress Towards a Daunting Goal

1997 • 9 citations