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Unique pattern of expression and inhibition of IL-1 signaling by the IL-1 receptor family member TIR8/SIGIRR.

Data up to Jan 2025

Published2004
Citations118
References30

Total Citations Per Year

Abstract

References (30)

Toll-Like Receptors

2003 • 6,127 citations

Toll-like receptors and innate immunity

2001 • 4,138 citations

Toll-Like Receptor Signaling Pathways

2003 • 1,236 citations

IRAK (Pelle) Family Member IRAK-2 and MyD88 as Proximal Mediators of IL-1 Signaling

1997 • 1,159 citations

Interleukin-1 Type II Receptor: A Decoy Target for IL-1 That Is Regulated by IL-4

1993 • 972 citations

Interleukin-1 Receptor Antagonist

1993 • 670 citations

Bacterial Lipopolysaccharide Activates Nuclear Factor-κB through Interleukin-1 Signaling Mediators in Cultured Human Dermal Endothelial Cells and Mononuclear Phagocytes

1999 • 610 citations

The Human Toll Signaling Pathway: Divergence of Nuclear Factor κB and JNK/SAPK Activation Upstream of Tumor Necrosis Factor Receptor–associated Factor 6 (TRAF6)

1998 • 581 citations

SIGIRR, a negative regulator of Toll-like receptor–interleukin 1 receptor signaling

2003 • 580 citations

IL-10 prevents the differentiation of monocytes to dendritic cells but promotes their maturation to macrophages

1998 • 505 citations

Inhibition of Interleukin 1 Receptor/Toll-like Receptor Signaling through the Alternatively Spliced, Short Form of MyD88 Is Due to Its Failure to Recruit IRAK-4

2003 • 494 citations

The type II ‘decoy’ receptor: A novel regulatory pathway for interleukin 1

1994 • 382 citations

The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells

2003 • 381 citations

Decoy receptors: a strategy to regulate inflammatory cytokines and chemokines

2001 • 363 citations

The Interleukin-1 Receptor Accessory Protein (IL-1RAcP) Is Essential for IL-1-induced Activation of Interleukin-1 Receptor-associated Kinase (IRAK) and Stress-activated Protein Kinases (SAP Kinases)

1997 • 311 citations

Stimulation of toll-like receptor 4 expression in human mononuclear phagocytes by interferon-γ: a molecular basis for priming and synergism with bacterial lipopolysaccharide

2002 • 289 citations

Fibronectin and vitronectin regulate the organization of their respective Arg-Gly-Asp adhesion receptors in cultured human endothelial cells.

1988 • 256 citations

A Novel Pathway Regulating Lipopolysaccharide-Induced Shock by ST2/T1 Via Inhibition of Toll-Like Receptor 4 Expression

2001 • 247 citations

Selective immortalization of murine macrophages from fresh bone marrow by a raf/myc recombinant murine retrovirus

1985 • 246 citations

A General Strategy for Isolation of Endothelial Cells From Murine Tissues

1997 • 232 citations

Protein overload-induced NF-kappaB activation in proximal tubular cells requires H(2)O(2) through a PKC-dependent pathway.

2002 • 216 citations

IDENTIFICATION AND CHARACTERIZATION OF SIGIRR, A MOLECULE REPRESENTING A NOVEL SUBTYPE OF THE IL-1R SUPERFAMILY

1999 • 179 citations

Interleukin-1 beta and tumor necrosis factor-alpha induce gene expression and production of leukocyte chemotactic factors, colony-stimulating factors, and interleukin-6 in human mesangial cells.

1991 • 159 citations

Transforming Growth Factor-β1 Is Up-Regulated by Podocytes in Response to Excess Intraglomerular Passage of Proteins

2002 • 147 citations

Cloning and characterization of a new isoform of the interleukin 1 receptor antagonist.

1995 • 122 citations

IL-1 Signaling Cascade in Liver Cells and the Involvement of a Soluble Form of the IL-1 Receptor Accessory Protein

2000 • 111 citations

Characterization of Signaling Pathways Activated by the Interleukin 1 (IL-1) Receptor Homologue T1/ST2

2002 • 87 citations

Migration of natural killer cells across endothelial cell monolayers.

1993 • 68 citations

Bacterial Lipopolysaccharide Causes Rapid Shedding, Followed by Inhibition of mRNA Expression, of the IL-1 Type II Receptor, with Concomitant Up-Regulation of the Type I Receptor and Induction of Incompletely Spliced Transcripts

1999 • 63 citations

DIVERGENT EFFECTS OF LPS ON EXPRESSION OF IL-1 RECEPTOR FAMILY MEMBERS IN MONONUCLEAR PHAGOCYTES IN VITRO AND IN VIVO

1998 • 43 citations

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