Evidence for involvement of guanine nucleotide‐binding regulatory proteins in the activation of phospholipases by hormones

G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALS

1987 • 6,374 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Cyclic GMP Cascade of Vision

1986 • 1,168 citations

Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase

1985 • 960 citations

5-Hydroxytryptamine stimulates inositol phosphate production in a cell-free system from blowfly salivary glands. Evidence for a role of GTP in coupling receptor activation to phosphoinositide breakdown.

1985 • 429 citations

Phospholipase A2 and phospholipase C are activated by distinct GTP-binding proteins in response to alpha 1-adrenergic stimulation in FRTL5 thyroid cells.

1986 • 424 citations

Fluoroaluminates activate transducin‐GDP by mimicking the γ‐phosphate of GTP in its binding site

1985 • 420 citations

An M2 Muscarinic Receptor Subtype Coupled to Both Adenylyl Cyclase and Phosphoinositide Turnover

1987 • 398 citations

Hormone-stimulated polyphosphoinositide breakdown in rat liver plasma membranes. Roles of guanine nucleotides and calcium.

1986 • 378 citations

Polyphosphoinositide phosphodiesterase: regulation by a novel guanine nucleotide binding protein, Gp

1987 • 356 citations

Interleukin 1 activates phospholipase A2 in rabbit chondrocytes: a possible signal for IL 1 action.

1986 • 259 citations

Purification and characterization of two immunologically distinct phosphoinositide-specific phospholipases C from bovine brain.

1987 • 243 citations

Receptor-Induced Diacylglycerol Formation in Permeabilized Platelets; Possible Role for a Gtp-Binding Protein

1984 • 206 citations

Evidence that Na+/H+ exchange regulates receptor-mediated phospholipase A2 activation in human platelets.

1986 • 196 citations

Coupling of photoexcited rhodopsin to inositol phospholipid hydrolysis in fly photoreceptors.

1987 • 193 citations

Light activation of phospholipase A2 in rod outer segments of bovine retina and its modulation by GTP-binding proteins.

1987 • 186 citations

(³H)-Vasopressin Binding to Isolated Rat Hepatocytes and Liver Membranes: Regulation by GTP and Relation to Glycogen Phosphorylase Activation

1980 • 163 citations

Regulation of phosphoinositide breakdown by guanine nucleotides

1986 • 160 citations

Guanosine 5'-O-thiotriphosphate stimulates phospholipase C activity in plasma membranes of rat hepatocytes.

1985 • 154 citations

Receptor coupling to polyphosphoinositide turnover: a parallel with the adenylate cyclase system

1986 • 128 citations

Guanine nucleotides stimulate soluble phosphoinositide-specific phospholipase C in the absence of membranes.

1986 • 116 citations

Effects of pertussis toxin treatment on the metabolism of rat adipocytes.

1983 • 112 citations

Purification and immunochemical characterization of the major pertussis‐toxin‐sensitive guanine‐nucleotide‐binding protein of bovine‐neutrophil membranes

1987 • 110 citations

Guanine nucleotide and NaF stimulation of phospholipase C activity in rat cerebral-cortical membranes. Studies on substrate specificity

1987 • 94 citations

Thrombin- and nucleotide-activated phosphatidylinositol 4,5-bisphosphate phospholipase C in human platelet membranes.

1987 • 86 citations

Regulation of a liver plasma membrane phosphoinositide phosphodiesterase by guanine nucleotides and calcium

1985 • 83 citations

5-Methyltryptamine stimulates phospholipase C-mediated breakdown of exogenous phosphoinositides by blowfly salivary gland membranes.

1985 • 81 citations

Solubilization of the vasopressin receptor from rat liver plasma membranes. Evidence for a receptor X GTP-binding protein complex.

1986 • 73 citations

Activation of membrane phospholipase C by vasopressin

1986 • 65 citations

Thyrotropin-releasing hormone stimulates GTP hydrolysis by membranes from GH4C1 rat pituitary tumor cells.

1984 • 62 citations

Purification and characterization of the rat liver vasopressin (V1) receptor.

1987 • 39 citations

Evidence that thyrotropin-releasing hormone-induced increases in GTPase activity and phosphoinositide metabolism in GH3 cells are mediated by a guanine nucleotide-binding protein other than GS or Gi

1986 • 34 citations

Guanine nucleotide regulation of [3H]vasopressin binding to liver plasma membranes and solubilized receptors Evidence for the involvement of a guanine nucleotide regulatory protein

1986 • 27 citations

Stimulation of specific GTPase activity by vasopressin in isolated membranes from cultured rat hepatocytes

1985 • 24 citations

Guanine nucleotide and pyrophosphate activate exogenous phosphatidylinositol 4,5-bisphosphate hydrolysis in rat liver plasma membranes

1987 • 21 citations

Thyroliberin action in pituitary cells is not inhibited by pertussis toxin

1986 • 12 citations