Thyroliberin action in pituitary cells is not inhibited by pertussis toxin

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Calcium homeostasis in intact lymphocytes: cytoplasmic free calcium monitored with a new, intracellularly trapped fluorescent indicator.

1982 • 2,255 citations

Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands

1982 • 2,148 citations

Isolation of two proteins with high affinity for guanine nucleotides from membranes of bovine brain.

1984 • 1,300 citations

Role of guanine nucleotide binding protein in the activation of polyphosphoinositide phosphodiesterase

1985 • 960 citations

Catecholamine-stimulated GTPase activity in turkey erythrocyte membranes

1976 • 623 citations

The polyphosphoinositide phosphodiesterase of erythrocyte membranes

1981 • 614 citations

Purification and properties of the inhibitory guanine nucleotide regulatory unit of brain adenylate cyclase.

1984 • 585 citations

Simultaneous inhibitions of inositol phospholipid breakdown, arachidonic acid release, and histamine secretion in mast cells by islet-activating protein, pertussis toxin. A possible involvement of the toxin-specific substrate in the Ca2+-mobilizing receptor-mediated biosignaling system.

1985 • 509 citations

Involvement of guanine nucleotide-binding protein in the gating of Ca2+ by receptors

1983 • 473 citations

5-Hydroxytryptamine stimulates inositol phosphate production in a cell-free system from blowfly salivary glands. Evidence for a role of GTP in coupling receptor activation to phosphoinositide breakdown.

1985 • 429 citations

Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin

1984 • 418 citations

ADP-ribosylation of the specific membrane protein by islet-activating protein, pertussis toxin, associated with inhibition of a chemotactic peptide-induced arachidonate release in neutrophils. A possible role of the toxin substrate in Ca2+-mobilizing biosignaling.

1984 • 389 citations

Chemoattractant receptor-induced hydrolysis of phosphatidylinositol 4,5-bisphosphate in human polymorphonuclear leukocyte membranes. Requirement for a guanine nucleotide regulatory protein.

1985 • 358 citations

Mechanism of Thyrotropin Releasing Hormone Stimulation of Pituitary Hormone Secretion

1986 • 292 citations

Pertussis toxin does not inhibit muscarinic-receptor-mediated phosphoinositide hydrolysis or calcium mobilization

1985 • 284 citations

Coupling of the guanine nucleotide regulatory protein to chemotactic peptide receptors in neutrophil membranes and its uncoupling by islet-activating protein, pertussis toxin. A possible role of the toxin substrate in Ca2+-mobilizing receptor-mediated signal transduction.

1985 • 281 citations

Receptor-mediated inhibition of adenylate cyclase and stimulation of arachidonic acid release in 3T3 fibroblasts. Selective susceptibility to islet-activating protein, pertussis toxin.

1985 • 245 citations

Receptor-Induced Diacylglycerol Formation in Permeabilized Platelets; Possible Role for a Gtp-Binding Protein

1984 • 206 citations

Receptors for Thyrotropin-releasing Hormone in Prolactin-producing Rat Pituitary Cells in Culture

1973 • 206 citations

Pertussis toxin blocks both cyclic AMP-mediated and cyclic AMP-independent actions of somatostatin. Evidence for coupling of Ni to decreases in intracellular free calcium.

1985 • 190 citations

Thyrotropin-releasing hormone stimulates rapid loss of phosphatidylinositol and its conversion to 1,2-diacylglycerol and phosphatidic acid in rat mammotropic pituitary cells. Association with calcium mobilization and prolactin secretion.

1983 • 181 citations

Pertussis toxin inhibits the rise in the intracellular concentration of free calcium that is induced by chemotactic factors in rabbit neutrophils: Possible role of the “G proteins” in calcium mobilization

1984 • 180 citations

Pertussis toxin inhibits fMet-Leu-Phe- but not phorbol ester-stimulated changes in rabbit neutrophils: role of G proteins in excitation response coupling.

1985 • 175 citations

Thyrotropin-releasing hormone and GTP activate inositol trisphosphate formation in membranes isolated from rat pituitary cells.

1986 • 169 citations

Association of the N-formyl-Met-Leu-Phe receptor in human neutrophils with a GTP-binding protein sensitive to pertussis toxin.

1985 • 159 citations

A Possible Role of Cyclic AMP in Mediating the Effects of Thyrotropin-Releasing Hormone on Prolactin Release and on Prolactin and Growth Hormone Synthesis in Pituitary Cells in Culture

1976 • 157 citations

CALCIUM INFLUX IS NOT REQUIRED FOR TRH TO ELEVATE FREE CYTOPLASMIC CALCIUM IN GH₃CELLS

1983 • 133 citations

Direct stimulation by thyrotropin-releasing hormone (TRH) of polyphosphoinositide hydrolysis in GH3 cell membranes by a guanine nucleotide-modulated mechanism

1985 • 99 citations

Islet‐activating protein, pertussis toxin, inhibits Ca²⁺‐induced and guanine nucleotide‐dependent releases of histamine and arachidonic acid from rat mast cells

1984 • 96 citations

Thyrotropin-releasing hormone-stimulated [3H]inositol metabolism in GH3 pituitary tumor cells. Studies with lithium.

1984 • 89 citations

Human Pancreatic Tumor Growth Hormone (GH)-Releasing Factor and Cyclic Adenosine 3′,5′-Monophosphate Evoke GH Release from Anterior Pituitary Cells: The Effects of Pertussis Toxin, Cholera Toxin, Forskolin, and Cycloheximide^*

1984 • 79 citations

Guanine nucleotide-sensitive, high affinity binding of carbachol to muscarinic cholinergic receptors of 1321N1 astrocytoma cells is insensitive to pertussis toxin.

1985 • 78 citations

Regulation of thyrotropin-releasing hormone binding by monovalent cations and guanyl nucleotides.

1984 • 72 citations

Receptor-mediated activation of a phospholipase A2 in rabbit neutrophil plasma membrane.

1984 • 66 citations

Thyrotropin-releasing hormone stimulates GTP hydrolysis by membranes from GH4C1 rat pituitary tumor cells.

1984 • 62 citations

Evidence for tight coupling of thyrotropin-releasing hormone receptors to stimulated inositol trisphosphate formation in rat pituitary cells.

1985 • 60 citations

Mechanisms and components involved in adenylate cyclase inhibition by hormones.

1984 • 55 citations

Regulation of Ca2+-dependent cyclic AMP accumulation and Ca2+ metabolism in intact pituitary tumor cells by modulators of prolactin production.

1983 • 43 citations

Thyrotropin (TSH)-Releasing Hormone Decreases Phosphatidylinositol and Increases Unesterified Arachidonic Acid in Thyrotropic Cells: Possible Early Events in Stimulation of TSH Secretion*

1984 • 42 citations

Control of adenylate cyclase activity by G proteins.

1985 • 28 citations

The relationship between pertussis-toxin-induced ADP-ribosylation of a plasma-membrane protein and reversal of muscarinic inhibition of prolactin secretion in GH3 cells

1984 • 26 citations

Pertussis toxin blocks the inhibitory effect of muscarinic cholinergic agonists on cyclic AMP accumulation and prolactin secretion in GH3 anterior-pituitary tumour cells

1984 • 25 citations

Pertussis toxin: lessons from biological and biochemical effects in different cells.

1984 • 19 citations