Simian virus 40 minichromosomes contain torsionally strained DNA molecules.

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

A Film Detection Method for Tritium‐Labelled Proteins and Nucleic Acids in Polyacrylamide Gels

1974 • 8,693 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold

1984 • 1,088 citations

The structure of histone-depleted metaphase chromosomes

1977 • 1,083 citations

DNA Gyrase and the Supercoiling of DNA

1980 • 713 citations

Determination of the number of superhelical turns in simian virus 40 DNA by gel electrophoresis.

1975 • 538 citations

Regulation of the genes for E. coli DNA gyrase: Homeostatic control of DNA supercoiling

1983 • 458 citations

Chromatin assembly in Xenopus oocytes: In vivo studies

1984 • 404 citations

Torsional tension in the DNA double helix measured with trimethylpsoralen in living E. coli cells: Analogous measurements in insect and human cells

1980 • 394 citations

Absence of nucleosomes in a fraction of SV40 chromatin between the origin of replication and the region coding for the late leader RNA

1980 • 372 citations

Linking numbers and nucleosomes.

1976 • 291 citations

A stretch of “late” SV40 viral DNA about 400 bp long which includes the origin of replication is specifically exposed in SV40 minichromosomes

1979 • 278 citations

DNA Supercoiling and Its Effects on DNA Structure and Function

1983 • 243 citations

The problems of eukaryotic and prokaryotic DNA packaging and in vivo conformation posed by superhelix density heterogeneity

1977 • 233 citations

Sites in simian virus 40 chromatin which are preferentially cleaved by endonucleases

1978 • 230 citations

Cruciform formation in a negatively supercoiled DNA may be kinetically forbidden under physiological conditions

1983 • 212 citations

[3] An integrated and simplified approach to cloning into plasmids and single-stranded phages

1983 • 210 citations

Cleavage of Circular, Superhelical Simian Virus 40 DNA to a Linear Duplex by S ₁ Nuclease

1973 • 207 citations

Defective simian virus 40 genomes: Isolation and growth of individual clones

1974 • 201 citations

Higher Order Structure of Simian Virus 40 Chromatin

1978 • 169 citations

SV40 viral minichromosome: preferential exposure of the origin of replication as probed by restriction endonucleases

1978 • 163 citations

Torsional stress promotes the DNAase I sensitivity of active genes

1984 • 145 citations

Elastic torsional strain in DNA within a fraction of SV40 minichromosomes: relation to transcriptionally active chromatin.

1982 • 134 citations

Origin of DNA replication in papovavirus chromatin is recognized by endogenous endonuclease.

1978 • 121 citations

The template of the isolated native simian virus 40 transcriptional complexes is a minichromosome

1979 • 79 citations

Staphylococcal nuclease makes a single non-random cut in the simian virus 40 viral minichromosome

1979 • 66 citations

Regulation of DNA Supercoiling in Escherichia coli

1983 • 65 citations

Association of eukaryotic DNA topoisomerase I with nucleosomes and chromosomal proteins

1983 • 63 citations

On the Structure of Eukaryotic, Prokaryotic, and Viral Chromatin

1978 • 61 citations

Isolation of two forms of SV40 nucleoprotein containing RNA polymerase from infected monkey cells

1976 • 57 citations

Quantitation of transcribing native simian virus 40 minichromosomes extracted from CV1 cells late in infection

1981 • 44 citations

Nicking-closing enzyme is associated with SV40 DNA in vivo as a sodium dodecyl sulfate-resistant complex

1979 • 27 citations

Polyoma virus minichromosomes: associated enzyme activities

1981 • 22 citations

Interaction of the DNA untwisting enzyme with the SV40 nucleoprotein complex

1978 • 17 citations

New way to isolate simian virus 40 nucleoprotein complexes from infected cells: use of a thiol-specific reagent

1982 • 13 citations

Polyomavirus minichromosomes: associated DNA topoisomerase II and DNA ligase activities

1984 • 9 citations

In vitro formation of multimeric DNA structures mediated by purified simian virus 40 chromatin.

1982 • 8 citations