Torsional tension in the DNA double helix measured with trimethylpsoralen in living E. coli cells: Analogous measurements in insect and human cells

Discontinuities in the DNA synthesized in an Excision-defective strain of Escherichia coli following ultraviolet irradiation

1968 • 1,089 citations

DNA Gyrase and the Supercoiling of DNA

1980 • 713 citations

On the structure of the folded chromosome of Escherichia coli

1972 • 635 citations

Folding of the DNA double helix in chromatin-like structures from simian virus 40.

1975 • 597 citations

Conformational fluctuations of DNA helix.

1975 • 562 citations

Isolation, characterization, and structure of the folded interphase genome of Drosophila melanogaster

1976 • 556 citations

Type II DNA topoisomerases: Enzymes that can unknot a topologically knotted DNA molecule via a reversible double-strand break

1980 • 547 citations

Determination of the number of superhelical turns in simian virus 40 DNA by gel electrophoresis.

1975 • 538 citations

Supercoils in human dna

1975 • 496 citations

E. coli DNA binding protein HU forms nucleosome-like structure with circular double-stranded DNA

1979 • 459 citations

Assembly of SV40 chromatin in a cell-free system from Xenopus eggs

1977 • 358 citations

Escherichia coli Mutants Thermosensitive for Deoxyribonucleic Acid Gyrase Subunit A: Effects on Deoxyribonucleic Acid Replication, Transcription, and Bacteriophage Growth

1979 • 337 citations

Characterization of a novel, low-molecular-weight DNA-binding protein from Escherichia coli.

1975 • 331 citations

Light-induced cross-linking of DNA in the presence of a furocoumarin (psoralen)

1970 • 322 citations

STRUCTURE AND REACTIONS OF CLOSED DUPLEX DNA

1978 • 316 citations

Synthesis and characterization of new psoralen derivatives with superior photoreactivity with DNA and RNA

1977 • 314 citations

Density alterations associated with transducing ability in the bacteriophage lambda

1959 • 313 citations

DNA gyrase: subunit structure and ATPase activity of the purified enzyme.

1978 • 282 citations

Purification of subunits of Escherichia coli DNA gyrase and reconstitution of enzymatic activity

1978 • 250 citations

Thermodynamic properties of superhelical DNAs

1975 • 229 citations

PHOTOREACTIONS AT 3655Å BETWEEN PYRIMIDINE BASES AND SKIN‐PHOTOSENSITIZING FUROCOUMARINS

1967 • 221 citations

Micrococcus luteus DNA gyrase: active components and a model for its supercoiling of DNA.

1978 • 206 citations

Superhelical Escherichia coli DNA: Relaxation by coumermycin

1978 • 203 citations

Modulation of gene expression by drugs affecting deoxyribonucleic acid gyrase

1979 • 197 citations

DNA-DNA gyrase complex: the wrapping of the DNA duplex outside the enzyme

1978 • 195 citations

RNA Molecules Bound to the Folded Bacterial Genome Stabilize DNA Folds and Segregate Domains of Supercoiling

1974 • 178 citations

Cross-Linking of DNA in Situ as a Probe for Chromatin Structure

1976 • 175 citations

Inactivation of Escherichia coli , F′ Episomes at Transfer, and Bacteriophage Lambda by Psoralen Plus 360-nm Light: Significance of Deoxyribonucleic Acid Cross-Links

1971 • 162 citations

PHOTOREACTIONS AT 3655 Å LINKING THE 3–4 DOUBLE BOND OF FUROCOUMARINS WITH PYRIMIDINE BASES

1967 • 143 citations

Plasmids containing many tandem copies of a synthetic lactose operator

1980 • 143 citations

Supercoils in prokaryotic DNA restrained in vivo.

1980 • 133 citations

Promoter-specific inhibition of transcription by antibiotics which act on DNA gyrase

1978 • 130 citations

Torsional stress and local denaturation in supercoiled DNA.

1979 • 119 citations

Dependence of mammalian DNA replication on DNA supercoiling II. Effects of novobiocin on DNA synthesis in Chinese hamster ovary cells

1979 • 114 citations

Coumermycin A1: a preferential inhibitor of replicative DNA synthesis in Escherichia coli. I. In vivo characterization

1976 • 106 citations

Binding of psoralen derivatives to DNA and chromatin: influence of the ionic environment on dark binding and photoreactivity

1978 • 88 citations

Electron microscopy of membrane-associated folded chromosomes of Escherichia coli

1976 • 88 citations

Nicking-closing enzyme assembles nucleosome-like structures in vitro.

1979 • 85 citations

Antagonists of DNA gyrase inhibit repair and recombination of UV-irradiated phage lambda.

1978 • 73 citations

Novobiocin—A specific inhibitor of semiconservative DNA replication in permeabilized Escherichia coli cells

1975 • 72 citations

Recombination promoted by superhelical DNA and the recA gene of Escherichia coli.

1976 • 64 citations

DNA unwinding induced by photoaddition of psoralen derivatives and determination of dark-binding equilibrium constants by gel electrophoresis

1978 • 59 citations

Interactions stabilizing DNA tertiary structure in the Escherichia coli chromosome investigated with ionizing radiation

1977 • 50 citations

Cloning of chemically synthesized lactose operators

1977 • 44 citations

SV40 DNA: Quantitative conversion of closed circular to open circular form by an ethidium bromide-restricted endonuclease

1973 • 38 citations

Cross-linking and relaxation of supercoiled DNA by psoralen and light

1978 • 24 citations

Chromatin Structure in Living Cells

1978 • 23 citations

Lengths of transcriptional units coding for the heat shock proteins in Drosophila melanogaster

1979 • 10 citations

Properties of Escherichia coli 16S ribosomal ribonucleic acid treated with 4,5',8-trimethylsoralen and light

1979 • 6 citations

Photoaddition of trimethylpsoralen as a probe for the intracellular organization of Eacherichia coli DNA

1980 • 2 citations