Crystal structure of enoyl-coenzyme A (CoA) hydratase at 2.5 angstroms resolution: a spiral fold defines the CoA-binding pocket.

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

Protein Structure Comparison by Alignment of Distance Matrices

1993 • 3,989 citations

WHAT IF: A molecular modeling and drug design program

1990 • 3,484 citations

Comparison of super-secondary structures in proteins

1973 • 885 citations

Crystal structure of porcine ribonuclease inhibitor, a protein with leucine-rich repeats

1993 • 614 citations

How coenzyme B12 radicals are generated: the crystal structure of methylmalonyl-coenzyme A mutase at 2 å resolution

1996 • 461 citations

The locked rotation function

1990 • 257 citations

Ancestry of the 4-chlorobenzoate dehalogenase: analysis of amino acid sequence identities among families of acyl:adenyl ligases, enoyl-CoA hydratases/isomerases, and acyl-CoA thioesterases

1992 • 194 citations

Doughnut-shaped structure of a bacterial muramidase revealed by X-ray crystallography

1994 • 155 citations

Efficient Rebuilding of Protein Structures

1996 • 148 citations

The crystal structure of succinyl-CoA synthetase from Escherichia coli at 2.5-A resolution.

1994 • 123 citations

Enoyl Coenzyme A Hydratase (Crotonase)

1972 • 112 citations

Substrate Stereochemistry of the Enoyl‐CoA Hydratase Reaction

1975 • 86 citations

Molecular cloning and sequence analysis of the cDNA for rat mitochondrial enoyl‐CoA hydratase

1989 • 76 citations

Delta 3,delta 2-enoyl-CoA isomerases. Characterization of the mitochondrial isoenzyme in the rat.

1990 • 72 citations

Crotonase-catalyzed .beta.-elimination is concerted: a double isotope effect study

1991 • 72 citations

Menaquinone (vitamin K2) biosynthesis: nucleotide sequence and expression of the menB gene from Escherichia coli

1992 • 72 citations

Enoyl-CoA Hydratase and Isomerase form a Superfamily with a Common Active-Site Glutamate Residue

1995 • 72 citations

Amino acid sequence similarities of the mitochondrial short chain delta 3, delta 2-enoyl-CoA isomerase and peroxisomal multifunctional delta 3, delta 2-enoyl-CoA isomerase, 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase enzyme in rat liver. The proposed occurrence of isomerization and hydration in the same catalytic domain of the multifunctional enzyme

1991 • 63 citations

Importance of Historical Contingency in the Stereochemistry of Hydratase-Dehydratase Enzymes

1995 • 62 citations

Structure of triosephosphate isomerase fromEscherichia colidetermined at 2.6 Å resolution

1993 • 59 citations

Enoyl-Coenzyme A Hydratase-Catalyzed Exchange of the .alpha.-Protons of Coenzyme A Thiol Esters: A Model for an Enolized Intermediate in the Enzyme-Catalyzed Elimination?

1994 • 38 citations

Electronic Rearrangement Induced by Substrate Analog Binding to the Enoyl-CoA Hydratase Active Site: Evidence for Substrate Activation

1994 • 37 citations

Parallel β-domains: a new fold in protein structures

1994 • 30 citations

Crystallization experiments with 2-enoyl-CoA hydratase, using an automated `fast-screening' crystallization protocol

1994 • 29 citations

Purification and characterization of a plant peroxisomal Δ²,Δ³‐enoyl‐CoA isomerase acting on 3‐cis‐enoyl‐CoA and 3‐trans‐enoyl‐CoA

1991 • 27 citations

Glutamate 139 of the Large .alpha.-Subunit Is the Catalytic Base in the Dehydration of Both D- and L-3-Hydroxyacyl-Coenzyme A But Not in the Isomerization of .DELTA.3,.DELTA.2-Enoyl-Coenzyme A Catalyzed by the Multienzyme Complex of Fatty Acid Oxidation from Escherichia coli

1995 • 20 citations

Purification and Characterization of Bovine Liver.3-cis-2-trans-Enoyl-CoAIsomerase

1990 • 14 citations