Resistance to melanoma in mice immunized with semiallogeneic fibroblasts transfected with DNA from mouse melanoma cells.

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

1992 • 4,648 citations

A Gene Encoding an Antigen Recognized by Cytolytic T Lymphocytes on a Human Melanoma

1991 • 3,493 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

Tumor Antigens Recognized by T Lymphocytes

1994 • 1,238 citations

Cloning of the gene coding for a shared human melanoma antigen recognized by autologous T cells infiltrating into tumor.

1994 • 1,108 citations

Hypermutability and mismatch repair deficiency in RER+ tumor cells

1993 • 1,042 citations

The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas.

1993 • 986 citations

Treatment of Established Renal Cancer by Tumor Cells Engineered to Secrete Interleukin-4

1991 • 733 citations

A nonapeptide encoded by human gene MAGE-1 is recognized on HLA-A1 by cytolytic T lymphocytes directed against tumor antigen MZ2-E.

1992 • 694 citations

BAGE: a new gene encoding an antigen recognized on human melanomas by cytolytic T lymphocytes

1995 • 598 citations

A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.

1995 • 591 citations

Melanocyte lineage-specific antigen gp100 is recognized by melanoma-derived tumor-infiltrating lymphocytes.

1994 • 584 citations

Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation

1994 • 496 citations

A vector that replicates as a plasmid and can be efficiently selected in B-lymphoblasts transformed by Epstein-Barr virus.

1985 • 445 citations

Retroviral vector-mediated gamma-interferon gene transfer into tumor cells generates potent and long lasting antitumor immunity.

1990 • 414 citations

Instability of short tandem repeats (microsatellites) in human cancers

1994 • 413 citations

A peptide encoded by human gene MAGE‐3 and presented by HLA‐A2 induces cytolytic T lymphocytes that recognize tumor cells expressing MAGE‐3

1994 • 379 citations

Fibroblasts genetically engineered to secrete interleukin 12 can suppress tumor growth and induce antitumor immunity to a murine melanoma in vivo.

1994 • 335 citations

Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo.

1991 • 315 citations

Fibroblasts as Efficient Antigen-Presenting Cells in Lymphoid Organs

1995 • 308 citations

Genetic background alters the spectrum of tumors that develop in p53‐deficient mice

1993 • 284 citations

Murine tumor cells transduced with the gene for tumor necrosis factor-alpha. Evidence for paracrine immune effects of tumor necrosis factor against tumors.

1991 • 283 citations

Tumor suppression after tumor cell-targeted tumor necrosis factor alpha gene transfer.

1991 • 279 citations

Immune response in human melanoma after transfer of an allogeneic class I major histocompatibility complex gene with DNA–liposome complexes

1996 • 237 citations

Frequent microsatellite instability in primary small cell lung cancer.

1994 • 224 citations

Domain interactions of H–2 class I antigens alter cytotoxic T-cell recognition sites

1984 • 207 citations

Monocyte chemotactic cytokine gene transfer modulates macrophage infiltration, growth, and susceptibility to IL-2 therapy of a murine melanoma.

1992 • 205 citations

In vitro and in vivo targeting of gene expression to melanoma cells.

1993 • 190 citations

Rejection of mouse sarcoma cells after transfection of MHC class II genes.

1990 • 171 citations

Toward a Genetic Analysis of Tumor Rejection Antigens

1992 • 151 citations

Expression of murine interleukin 7 in a murine glioma cell line results in reduced tumorigenicity in vivo.

1992 • 140 citations

Identification of human melanoma peptides recognized by class I restricted tumor infiltrating T lymphocytes.

1993 • 140 citations

Genetic instability in human ovarian cancer cell lines.

1994 • 134 citations

Tumor antigens recognized by cytolytic T lymphocytes: Present perspectives for specific immunotherapy

1993 • 109 citations

Involvement of two Ets binding sites in the transcriptional activation of the MAGE1 gene

1995 • 93 citations

Decreased tumorigenicity of a transplantable rat sarcoma following transfer and expression of an IL‐2 cDNA

1991 • 92 citations

Fibrosarcoma cells transduced with the IL-6 gene exhibited reduced tumorigenicity, increased immunogenicity, and decreased metastatic potential.

1992 • 90 citations

Murine B7 antigen provides a sufficient costimulatory signal for antigen-specific and MHC-restricted T cell activation.

1992 • 83 citations

Protective and curative potential of vaccination with interleukin-2-gene-transfected cells from a spontaneous mouse mammary adenocarcinoma.

1993 • 83 citations

Tumor rejection mediated by transfection with allogeneic class I histocompatibility gene.

1989 • 76 citations

How Plants Make Oxygen

1990 • 72 citations

Alpha 1-interferon gene transfer into metastatic Friend leukemia cells abrogated tumorigenicity in immunocompetent mice: antitumor therapy by means of interferon-producing cells.

1993 • 65 citations

Interleukin-2-secreting mouse fibroblasts transfected with genomic DNA from murine melanoma cells prolong the survival of mice with melanoma.

1994 • 53 citations

Immunity to B16 melanoma in mice immunized with IL‐2‐secreting allogeneic mouse fibroblasts expressing melanoma‐associated antigens

1992 • 44 citations

Immunization with interleukin‐2‐secreting allogeneic mouse fibroblasts expressing melanoma‐associated antigens prolongs the survival of mice with melanoma

1993 • 25 citations

Immunization of Mice with Allogeneic Fibroblasts Genetically Modified for Interleukin-2-Secretion and Expression of Melanoma-Associated Antigens Stimulate Predetermined Classes of Anti-Melanoma Effector Cells

1994 • 16 citations

Tumorigenicity of interleukin-2 (IL-2)-cDNA-transfected L1210 lymphoma and its in vivo variants is modulated by changes in IL-2 expression; potential therapeutic implications

1992 • 13 citations

Interleukin-2-secreting mouse fibroblasts transfected with genomic DNA from murine neoplasms induce tumor-specific immune responses that prolong the lives of tumor-bearing mice.

1995 • 6 citations