Decreased tumorigenicity of a transplantable rat sarcoma following transfer and expression of an IL‐2 cDNA

A Laboratory manual

1989 • 6,833 citations

T Cell Growth Factor: Parameters of Production and a Quantitative Microassay for Activity

1978 • 3,314 citations

A Progress Report on the Treatment of 157 Patients with Advanced Cancer Using Lymphokine-Activated Killer Cells and Interleukin-2 or High-Dose Interleukin-2 Alone

1987 • 2,769 citations

Use of Tumor-Infiltrating Lymphocytes and Interleukin-2 in the Immunotherapy of Patients with Metastatic Melanoma

1988 • 2,196 citations

Interleukin-2: Inception, Impact, and Implications

1988 • 2,166 citations

Construction of a retrovirus packaging mutant and its use to produce helper-free defective retrovirus

1983 • 1,857 citations

TECHNOLOGICAL EXAMINATION OF LOW‐FIRED TERRACOTTA STATUES FROM AYIA IRINI, KEA

1982 • 1,253 citations

Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

1990 • 926 citations

T‐Cell Growth Factor

1980 • 917 citations

Safe and efficient generation of recombinant retroviruses with amphotropic and ecotropic host ranges.

1988 • 908 citations

Murine interleukin-4 displays potent anti-tumor activity in vivo

1989 • 790 citations

A new dominant hybrid selective marker for higher eukaryotic cells

1981 • 662 citations

The IL-2 Receptor β Chain (p70): Role in Mediating Signals for LAK, NK, and Proliferative Activities

1987 • 444 citations

TUMOUR-INFILTRATING LYMPHOCYTES AND INTERLEUKIN-2 IN TREATMENT OF ADVANCED CANCER

1989 • 337 citations

Effects of natural and recombinant IL 2 on regulation of IFN gamma production and natural killer activity: lack of involvement of the Tac antigen for these immunoregulatory effects.

1984 • 310 citations

Interleukin 2 receptors on human B cells. Implications for the role of interleukin 2 in human B cell function.

1985 • 249 citations

Two dominant-acting selectable markers for gene transfer studies in mammalian cells.

1988 • 184 citations

Mechanism of Interleukin-2 Signaling: Mediation of Different Outcomes by a Single Receptor and Transduction Pathway

1989 • 148 citations

Retroviral expression of the human IL-2 gene in a murine T cell line results in cell growth autonomy and tumorigenicity.

1987 • 103 citations

Development of retrovirus vectors useful for expressing genes in cultured murine embryonal cells and hematopoietic cells in vivo

1988 • 102 citations

Identification of specific residues of human interleukin 2 that affect binding to the 70-kDa subunit (p70) of the interleukin 2 receptor.

1988 • 99 citations

Functional consequences of monocyte IL-2 receptor expression. Induction of IL-1 beta secretion by IFN gamma and IL-2.

1989 • 77 citations

Viral Xenogenization of Intact Tumor Cells

1979 • 71 citations

Lymphokine gene therapy for cancer

1990 • 58 citations

The bimolecular structure of the interleukin 2 receptor

1988 • 53 citations

Influence of Tumour Growth on the Evolution of Cytotoxic Lymphoid Cells in Rats Bearing a Spontaneously Metastasizing Syngeneic Fibrosarcoma

1973 • 49 citations

Effect of human recombinant IL-2 on murine macrophage precursors. Involvement of a receptor distinct from the p55 (Tac) protein.

1989 • 40 citations

Immunobiology and Immunotherapy of Cancer Metastases Ten-Year Studies in an Animal Model Resulting the Design of an Immunotherapy Procedure now under Clinical Testing

1989 • 11 citations

Interleukin-2 and T cell malignancies: an autocrine loop with a twist.

1989 • 5 citations