Selectively Reduced Expression of Synaptic Plasticity-Related Genes in Amyloid Precursor Protein + Presenilin-1 Transgenic Mice

Amyloid Oligomers Exacerbate Tau Pathology in a Mouse Model of Tauopathy

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Naturally secreted oligomers of amyloid β protein potently inhibit hippocampal long-term potentiation in vivo

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Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

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Genetic enhancement of learning and memory in mice

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Aβ peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

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Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes

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Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR

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Homer: a protein that selectively binds metabotropic glutamate receptors

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Inhibition of Activity-Dependent Arc Protein Expression in the Rat Hippocampus Impairs the Maintenance of Long-Term Potentiation and the Consolidation of Long-Term Memory

2000 • 1,007 citations

Consensus Recommendations for the Postmortem Diagnosis of Alzheimer’s Disease

1997 • 938 citations

Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice

1999 • 918 citations

A requirement for the immediate early gene Zif268 in the expression of late LTP and long-term memories

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Altered expression of synaptic proteins occurs early during progression of Alzheimer’s disease

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Homer Regulates the Association of Group 1 Metabotropic Glutamate Receptors with Multivalent Complexes of Homer-Related, Synaptic Proteins

1998 • 630 citations

The MAPK/ERK Cascade Targets Both Elk-1 and cAMP Response Element-Binding Protein to Control Long-Term Potentiation-Dependent Gene Expression in the Dentate GyrusIn Vivo

2000 • 609 citations

Synaptopodin: An Actin-associated Protein in Telencephalic Dendrites and Renal Podocytes

1997 • 593 citations

Beta-amyloid activates the mitogen-activated protein kinase cascade via hippocampal alpha7 nicotinic acetylcholine receptors: In vitro and in vivo mechanisms related to Alzheimer's disease.

2001 • 516 citations

Knockout of ERK1 MAP Kinase Enhances Synaptic Plasticity in the Striatum and Facilitates Striatal-Mediated Learning and Memory

2002 • 458 citations

β-Amyloid Activates the Mitogen-Activated Protein Kinase Cascade via Hippocampal α7 Nicotinic Acetylcholine Receptors:In VitroandIn VivoMechanisms Related to Alzheimer's Disease

2001 • 446 citations

Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease.

1997 • 419 citations

Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits.

1999 • 355 citations

Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes

2001 • 346 citations

An evaluation of the performance of cDNA microarrays for detecting changes in global mRNA expression

2001 • 313 citations

Expression profile of transcripts in Alzheimer's disease tangle-bearing CA1 neurons

2000 • 310 citations

A Gene Expression Profile of Alzheimer's Disease

2001 • 304 citations

Inflammatory Responses to Amyloidosis in a Transgenic Mouse Model of Alzheimer’s Disease

2001 • 292 citations

Lack of Neurodegeneration in Transgenic Mice Overexpressing Mutant Amyloid Precursor Protein Is Associated with Increased Levels of Transthyretin and the Activation of Cell Survival Pathways

2002 • 286 citations

Alterations in synaptic transmission and long-term potentiation in hippocampal slices from young and aged PDAPP mice

1999 • 273 citations

A Hippocampal NR2B Deficit Can Mimic Age-Related Changes in Long-Term Potentiation and Spatial Learning in the Fischer 344 Rat

2002 • 251 citations

Time Course of the Development of Alzheimer-like Pathology in the Doubly Transgenic PS1+APP Mouse

2002 • 245 citations

Recruitment of New Sites of Synaptic Transmission During the cAMP-Dependent Late Phase of LTP at CA3–CA1 Synapses in the Hippocampus

1997 • 225 citations

Dendritic and Axonal Targeting of Type 5 Metabotropic Glutamate Receptor Is Regulated by Homer1 Proteins and Neuronal Excitation

2000 • 224 citations

Age-Related Impairment of Synaptic Transmission But Normal Long-Term Potentiation in Transgenic Mice that Overexpress the Human APP695SWE Mutant Form of Amyloid Precursor Protein

2001 • 214 citations

Enhanced learning after genetic overexpression of a brain growth protein

2000 • 204 citations

Correlation between cognitive deficits and Aβ deposits in transgenic APP+PS1 mice

2001 • 199 citations

Staging of Cytoskeletal and β-Amyloid Changes in Human Isocortex Reveals Biphasic Synaptic Protein Response during Progression of Alzheimer’s Disease

2000 • 190 citations

Cyclic AMP induces functional presynaptic boutons in hippocampal CA3–CA1 neuronal cultures

1999 • 157 citations

Actin-associated protein synaptopodin in the rat hippocampal formation: Localization in the spine neck and close association with the spine apparatus of principal neurons

2000 • 133 citations

The decline in synapses and cholinergic activity is asynchronous in Alzheimer’s disease

2000 • 121 citations

N-methyl-d-aspartate receptor subunit NR2A and NR2B messenger RNA levels are altered in the hippocampus and entorhinal cortex in Alzheimer's disease

2002 • 105 citations

Synaptic Pathology in Prefrontal Cortex is Present Only with Severe Dementia in Alzheimer Disease

2001 • 81 citations

Regulated expression of an actin‐associated protein, synaptopodin, during long‐term potentiation

2001 • 67 citations

Short-term β-amyloid vaccinations do not improve cognitive performance in cognitively impaired APP+PS1 mice.

2003 • 46 citations