Analysis of Constitutive and Noninducible Mutations of the PUT3 Transcriptional Activator

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Experiments in molecular genetics

1972 • 28,260 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mpl8 and pUC19 vectors

1985 • 15,222 citations

A comprehensive set of sequence analysis programs for the VAX

1984 • 14,824 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Methods in yeast genetics

1979 • 7,824 citations

Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins

1978 • 4,566 citations

Rapid and Sensitive Protein Similarity Searches

1985 • 4,091 citations

Prediction of protein antigenic determinants from amino acid sequences.

1981 • 3,715 citations

Prediction of the Secondary Structure of Proteins from their Amino Acid Sequence

1979 • 2,930 citations

A ten-minute DNA preparation from yeast efficiently releases autonomous plasmids for transformaion of Escherichia coli

1987 • 2,493 citations

Repetitive zinc-binding domains in the protein transcription factor IIIA from Xenopus oocytes.

1985 • 2,450 citations

Codon selection in yeast.

1982 • 1,580 citations

Two differentially regulated mRNAs with different 5′ ends encode secreted and intracellular forms of yeast invertase

1982 • 1,539 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

DNA sequence required for efficient transcription termination in yeast

1982 • 1,014 citations

Sequences That Regulate the Divergent GAL1-GAL10 Promoter in Saccharomyces cerevisiae

1984 • 955 citations

Functional dissection of a eukaryotic transcriptional activator protein, GCN4 of Yeast

1986 • 946 citations

Deletion analysis of GAL4 defines two transcriptional activating segments

1987 • 898 citations

The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs

1981 • 819 citations

Separation of DNA Binding from the Transcription-Activating Function of a Eukaryotic Regulatory Protein

1986 • 626 citations

Yeast shuttle and integrative vectors with multiple cloning sites suitable for construction of lacZ fusions

1986 • 623 citations

Functional dissection and sequence of yeast HAP1 activator

1989 • 309 citations

Structural changes in glycogen phosphorylase induced by phosphorylation

1988 • 302 citations

Isolation of the yeast regulatory gene GAL4 and analysis of its dosage effects on the galactose/melibiose regulon.

1982 • 280 citations

The multidrug resistance gene PDR1 from Saccharomyces cerevisiae.

1987 • 276 citations

Primary Structure of the Saccharomyces cerevisiae GAL4 Gene

1984 • 276 citations

Cyclic AMP-dependent protein kinase phosphorylates and inactivates the yeast transcriptional activator ADR1

1989 • 247 citations

Review Lecture: Protein phosphorylation and hormone action

1988 • 237 citations

Interaction of positive and negative regulatory proteins in the galactose regulon of yeast

1987 • 226 citations

GAL4 transcription factor is not a "zinc finger" but forms a Zn(II)2Cys6 binuclear cluster.

1990 • 211 citations

Site specificity of casein kinase‐2 (TS) from rat liver cytosol

1986 • 193 citations

Genetic evidence that zinc is an essential co-factor in the DNA binding domain of GAL4 protein

1987 • 169 citations

Analysis of theKluyveromyces lactispositive regulatory geneLAC9reveals functional homology to, but sequence divergence from, theSaccharomyces cerevisiae GALAgene

1986 • 158 citations

Yeast regulatory gene PPR1

1984 • 141 citations

Regulation of expression of the galactose gene cluster in Saccharomyces cerevisiae

1983 • 131 citations

Characterization of a Positive Regulatory Gene, LAC9, That Controls Induction of the Lactose-Galactose Regulon of Kluyveromyces lactis: Structural and Functional Relationships to GAL4 of Saccharomyces cerevisiae

1987 • 128 citations

Two zinc fingers of a yeast regulatory protein shown by genetic evidence to be essential for its function

1987 • 128 citations

Genetics and physiology of proline utilization in Saccharomyces cerevisiae: enzyme induction by proline

1979 • 126 citations

Proline utilization in Saccharomyces cerevisiae: sequence, regulation, and mitochondrial localization of the PUT1 gene product.

1987 • 115 citations

Expression of qa-1F activator protein: identification of upstream binding sites in the qa gene cluster and localization of the DNA-binding domain.

1987 • 109 citations

Nucleotide sequence of putP, the proline carrier gene of Escherichia coli K12

1987 • 108 citations

Regulated phosphorylation and dephosphorylation of GAL4, a transcriptional activator.

1989 • 106 citations

Nucleotide sequence of the Saccharomyces cerevisiae PUT4 proline-permease-encoding gene: similarities between CAN1, HIP1 and PUT4 permeases

1989 • 106 citations

Functional Domains of a Positive Regulatory Protein, PH04, for Transcriptional Control of the Phosphatase Regulon in Saccharomyces cerevisiae

1990 • 106 citations

Mutations that inactivate a yeast transcriptional regulatory protein cluster in an evolutionarily conserved DNA binding domain.

1987 • 105 citations

Nucleotide sequence of the ARGRII regulatory gene and amino acid sequence homologies between ARGRII PPRI and GAL4 regulatory proteins

1986 • 100 citations

Structure and function of the Zn(II) binding site within the DNA-binding domain of the GAL4 transcription factor.

1989 • 89 citations

LEU3 of Saccharomyces cerevisiae encodes a factor for control of RNA levels of a group of leucine-specific genes.

1987 • 87 citations

The Saccharomyces cerevisiae PUT3 activator protein associates with proline-specific upstream activation sequences.

1989 • 75 citations

GAL4 Protein: Purification, Association with GAL80 Protein, and Conserved Domain Structure

1990 • 72 citations

Proline: an essential intermediate in arginine degradation in Saccharomyces cerevisiae

1980 • 71 citations

cAMP-dependent phosphorylation and inactivation of yeast transcription factor ADR1 does not affect DNA binding.

1990 • 71 citations

Structure of yeast regulatory geneLEU3and evidence thatLEU3itself is under general amino acid control

1987 • 67 citations

The proline transport protein of Aspergillus nidulans is very similar to amino acid transporters of Saccharomyces cerevisiae

1989 • 66 citations

Isolation and characterization of the positively acting regulatory geneQUTAfromAspergillus nidulans

1987 • 66 citations

Sequence and Functional Analysis of the Positively Acting Regulatory Gene amdR from Aspergillus nidulans

1990 • 63 citations

Proline-independent binding of PUT3 transcriptional activator protein detected by footprinting in vivo.

1991 • 62 citations

CYP1 (HAP1) regulator of oxygen-dependent gene expression in yeast

1988 • 61 citations

Phosphorylated forms of GAL4 are correlated with ability to activate transcription.

1990 • 59 citations

The MAL63 gene of Saccharomyces encodes a cysteine-zinc finger protein

1988 • 59 citations

Genetics and physiology of proline utilization in Saccharomyces cerevisiae: mutation causing constitutive enzyme expression

1979 • 56 citations

GAL4 mutations that separate the transcriptional activation and GAL80-interactive functions of the yeast GAL4 protein.

1990 • 54 citations

Nucleotide sequence ofCandida pelliculosaβ-glucosidase gene

1985 • 53 citations

Isolation and preliminary characterization of Saccharomyces cerevisiae proline auxotrophs

1979 • 50 citations

Constitutive RNA synthesis for the yeast activator ADR1 and identification of the ADR1-5c mutation: implications in posttranslational control of ADR1.

1986 • 47 citations

Direct selective techniques for the isolation of pyrimidine auxotrophs in yeast

1972 • 38 citations

Evidence for Positive Regulation of the Proline Utilization Pathway in Saccharomyces cerevisiae

1987 • 37 citations

Amino-terminal fragments of delta 1-pyrroline-5-carboxylate dehydrogenase direct beta-galactosidase to the mitochondrial matrix in Saccharomyces cerevisiae.

1986 • 29 citations

Isolation of Constitutive Mutations Affecting the Proline Utilization Pathway in Saccharomyces cerevisiae and Molecular Analysis of the PUT3 Transcriptional Activator

1989 • 29 citations

Primary structure of the regulatory gene from the MAL6 locus of Saccharomyces carlsbergensis

1988 • 28 citations