Effects of antipsychotic drugs on extracellular dopamine levels in rat medial prefrontal cortex and nucleus accumbens.

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Clozapine for the Treatment-Resistant Schizophrenic

1988 • 4,030 citations

Structure and function of the brain serotonin system

1992 • 2,507 citations

Dopamine in schizophrenia: a review and reconceptualization

1991 • 1,963 citations

D1 Dopamine Receptors in Prefrontal Cortex: Involvement in Working Memory

1991 • 1,365 citations

Classification of typical and atypical antipsychotic drugs on the basis of dopamine D-1, D-2 and serotonin2 pKi values.

1989 • 1,313 citations

Risperidone compared with new and reference antipsychotic drugs: in vitro and in vivo receptor binding

1996 • 1,143 citations

Radioreceptor Binding Profile of the Atypical Antipsychotic Olanzapine

1996 • 1,047 citations

Localization of dopamine D3 receptor mRNA in the rat brain using in situ hybridization histochemistry: comparison with dopamine D2 receptor mRNA

1991 • 859 citations

Multiple fixed doses of “Seroquel” (quetiapine) in patients with acute exacerbation of schizophrenia: A comparison with haloperidol and placebo

1997 • 756 citations

Increased dopamine turnover in the prefrontal cortex impairs spatial working memory performance in rats and monkeys.

1996 • 599 citations

Normalization of extracellular dopamine in striatum following recovery from a partial unilateral 6-OHDA lesion of the substantia nigra: a microdialysis study in freely moving rats

1988 • 516 citations

5-Hydroxytryptamine _2A serotonin receptors in the primate cerebral cortex: Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites

1998 • 510 citations

Cortical maldevelopment, anti-psychotic drugs, and schizophrenia: a search for common ground

1995 • 475 citations

Acute Effects of Typical and Atypical Antipsychotic Drugs on the Release of Dopamine from Prefrontal Cortex, Nucleus Accumbens, and Striatum of the Rat: An In Vivo Microdialysis Study

1990 • 407 citations

Does risperidone improve verbal working memory in treatment-resistant schizophrenia?

1997 • 406 citations

Improvement in cognitive functions and psychiatric symptoms in treatment-refractory schizophrenic patients receiving clozapine

1993 • 403 citations

Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors

1993 • 334 citations

Negative symptoms: a path analytic approach to a double-blind, placebo- and haloperidol-controlled clinical trial with olanzapine

1997 • 302 citations

Ritanserin, a 5-HT2 receptor antagonist, activates midbrain dopamine neurons by blocking serotonergic inhibition

1989 • 266 citations

Mechanisms of action of atypical antipsychotic drugs

1991 • 254 citations

Binding of typical and atypical antipsychotic agents to transiently expressed 5-HT1C receptors.

1992 • 192 citations

霊長類大脳皮質の5‐ヒドロキシトリプタミン2Aセロトニン受容体 錐体細胞先端樹状突起での幻覚剤及び抗精神病剤の作用部位

1998 • 183 citations

Characterization of typical and atypical antipsychotic drugs based on in vivo occupancy of serotonin2 and dopamine2 receptors.

1993 • 170 citations

In Vivo Assessment of Dopamine Uptake in Rat Medial Prefrontal Cortex: Comparison with Dorsal Striatum and Nucleus Accumbens

1995 • 143 citations

D4 dopamine receptor binding affinity does not distinguish between typical and atypical antipsychotic drugs

1995 • 143 citations

Neurochemical evidence for antagonism by olanzapine of dopamine, serotonin, α1-adrenergic and muscarinic receptors in vivo in rats

1996 • 131 citations

Systemic administration of amperozide, a new atypical antipsychotic drug, preferentially increases dopamine release in the rat medial prefrontal cortex

1994 • 126 citations

On the mechanism of neuroleptic induced increase in striatal dopamine release: Brain dialysis provides direct evidence for mediation by autoreceptors localized on nerve terminals

1989 • 125 citations

The selective 5-HT2A receptor antagonist, MDL 100,907, increases dopamine efflux in the prefrontal cortex of the rat

1995 • 118 citations

Risperidone: regional effects in vivo on release and metabolism of dopamine and serotonin in the rat brain

1996 • 112 citations

Ritanserin potentiates the stimulatory effects of raclopride on neuronal activity and dopamine release selectively in the mesolimbic dopaminergic system

1995 • 90 citations

BIMG 80, a Novel Potential Antipsychotic Drug: Evidence for Multireceptor Actions and Preferential Release of Dopamine in Prefrontal Cortex

1997 • 88 citations

Differential Effects of Locally Administered Clozapine and Haloperidol on Dopamine Efflux in the Rat Prefrontal Cortex and Caudate‐Putamen

1994 • 80 citations

Deriving the therapeutic concentrations for clozapine and haloperidol: The apparent dissociation constant of a neuroleptic at the dopamine D2 or D4 receptor varies with the affinity of the competing radioligand

1995 • 73 citations

A Risk-Benefit Assessment of Sulpiride in the Treatment of Schizophrenia

1996 • 64 citations

R(+)-8-OH-DPAT, a 5-HT1A receptor agonist, inhibits amphetamine-induced serotonin and dopamine release in rat medial prefrontal cortex

1996 • 55 citations

Studies of four novel diphenylbutylpiperazinepyridyl derivatives on release and inhibition of reuptake of dopamine, serotonin and noradrenaline by rat brain in vitro

1995 • 14 citations