Randomized trial comparing monthly low-dose leucovorin and fluorouracil bolus with bimonthly high-dose leucovorin and fluorouracil bolus plus continuous infusion for advanced colorectal cancer: a French intergroup study.

Nonparametric Estimation from Incomplete Observations

1992 • 45,923 citations

Regression Models and Life-Tables

1992 • 27,454 citations

Statistical Aspects of the Analysis of Data From Retrospective Studies of Disease

1959 • 14,850 citations

Modulation of fluorouracil by leucovorin in patients with advanced colorectal cancer: evidence in terms of response rate. Advanced Colorectal Cancer Meta-Analysis Project.

1992 • 1,198 citations

Biochemical modulation of fluorouracil: evidence of significant improvement of survival and quality of life in patients with advanced colorectal carcinoma.

1989 • 911 citations

Fluorouracil: biochemistry and pharmacology.

1988 • 825 citations

A prospective randomized comparison of continuous infusion fluorouracil with a conventional bolus schedule in metastatic colorectal carcinoma: a Mid-Atlantic Oncology Program Study.

1989 • 781 citations

The modulation of fluorouracil with leucovorin in metastatic colorectal carcinoma: a prospective randomized phase III trial. Gastrointestinal Tumor Study Group.

1989 • 561 citations

A prospective randomized trial of 5-fluorouracil versus 5-fluorouracil and high-dose leucovorin versus 5-fluorouracil and methotrexate in previously untreated patients with advanced colorectal carcinoma.

1987 • 452 citations

Treatment of advanced colorectal and gastric adenocarcinomas with 5-fluorouracil and high-dose folinic acid.

1986 • 402 citations

Biochemical modulation of fluorouracil with leucovorin: confirmatory evidence of improved therapeutic efficacy in advanced colorectal cancer.

1991 • 377 citations

Phase II study of fluorouracil and its modulation in advanced colorectal cancer: a Southwest Oncology Group study.

1995 • 365 citations

Randomized comparison of two schedules of fluorouracil and leucovorin in the treatment of advanced colorectal cancer.

1994 • 316 citations

High-dose folinic acid and 5-fluorouracil bolus and continuous infusion in advanced colorectal cancer

1988 • 131 citations

5-Fluorouracil and folinic acid in the treatment of metastatic colorectal cancer: a randomized comparison. A Southwest Oncology Group Study.

1987 • 84 citations

Randomized trial assessing the addition of interferon alpha-2a to fluorouracil and leucovorin in advanced colorectal cancer. Colorectal Cancer Working Party of the United Kingdom Medical Research Council.

1996 • 84 citations

Synergism and Lack of Cross-resistance Between Short-term and Continuous Exposure to Fluorouracil in Human Colon Adenocarcinoma Cells

1993 • 82 citations

Activity of continuous-infusion 5-fluorouracil in patients with advanced colorectal cancer clinically resistant to bolus 5-fluorouracil

1993 • 49 citations

A less toxic regimen of 5-fluorouracil and high-dose folinic acid for advanced gastrointestinal adenocarcinomas

1991 • 38 citations

Preliminary Evidence that Incorporation of 5-Fluorouracil into RNA Correlates with Antitumor Response

1992 • 35 citations

Randomized comparison of fluorouracil and leucovorin therapy versus fluorouracil, leucovorin, and cisplatin therapy in patients with advanced colorectal cancer

1994 • 27 citations

Dual modulation of 5-fluorouracil with folinic acid and hydroxyurea in metastatic colorectal cancer.

1996 • 13 citations