The tolkin gene is a tolloid/BMP-1 homologue that is essential for Drosophila development.

Basic Local Alignment Search Tool

1990 • 12,947 citations

Improved tools for biological sequence comparison.

1988 • 11,455 citations

Novel Regulators of Bone Formation: Molecular Clones and Activities

1988 • 3,919 citations

A non-radioactive in situ hybridization method for the localization of specific RNAs in Drosophila embryos reveals translational control of the segmentation gene hunchback

1989 • 2,555 citations

Automation of the computer handling of gel reading data produced by the shotgun method of DNA sequencing

1982 • 744 citations

The engrailed locus of drosophila: Structural analysis of an embryonic transcript

1985 • 735 citations

Latent high molecular weight complex of transforming growth factor beta 1. Purification from human platelets and structural characterization.

1988 • 648 citations

Functional cDNA libraries from Drosophila embryos

1988 • 604 citations

The mouse short ear skeletal morphogenesis locus is associated with defects in a bone morphogenetic member of the TGFβ superfamily

1992 • 483 citations

Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases

1992 • 319 citations

Structure and function of epidermal growth factor‐like regions in proteins

1988 • 305 citations

The decapentaplegic gene is required for dorsal-ventral patterning of the Drosophila embryo.

1987 • 288 citations

Human BMP sequences can confer normal dorsal-ventral patterning in the Drosophila embryo.

1993 • 283 citations

Receptor serine/threonine kinases implicated in the control of Drosophila body pattern by decapentaplegic

1994 • 275 citations

Families of metalloendopeptidases and their relationships

1992 • 195 citations

Loss of gene function through rapid mitotic cycles in the Drosophila embryo

1992 • 150 citations

Early mRNAs, spatially restricted along the animal-vegetal axis of sea urchin embryos, include one encoding a protein related to tolloid and BMP-1

1992 • 128 citations

A computer program to enter DNA gel reading data into a computer

1984 • 123 citations

Separable cis-acting control elements for expression of the white gene of Drosophila.

1985 • 123 citations

Implications of the three‐dimensional structure of astacin for the structure and function of the astacin family of zinc‐endopeptidases

1993 • 111 citations

Characterization of tolloid-related-1: A BMP-1-like Product That Is Required during Larval and Pupal Stages of Drosophila Development

1994 • 69 citations

Functional model of subcomponent C1 of human complement

1986 • 55 citations

Cloning and expression of cDNA encoding Xenopus laevis bone morphogenetic protein-1 during early embryonic development

1993 • 42 citations