Structure of astacin and implications for activation of astacins and zinc-ligation of collagenases

The protein data bank: A computer-based archival file for macromolecular structures

1977 • 8,627 citations

Novel Regulators of Bone Formation: Molecular Clones and Activities

1988 • 3,919 citations

Zinc coordination, function, and structure of zinc enzymes and other proteins

1990 • 1,731 citations

Multiple modes of activation of latent human fibroblast collagenase: evidence for the role of a Cys73 active-site zinc complex in latency and a "cysteine switch" mechanism for activation.

1990 • 699 citations

Structural basis of the action of thermolysin and related zinc peptidases

1988 • 675 citations

Structural basis of the activation and action of trypsin

1978 • 669 citations

Human fibroblast collagenase. Complete primary structure and homology to an oncogene transformation-induced rat protein.

1986 • 645 citations

Comparison of human stromelysin and collagenase by cloning and sequence analysis

1986 • 443 citations

Crystal orientation and X-ray pattern prediction routines for area-detector diffractometer systems in macromolecular crystallography

1987 • 396 citations

Refinement of large structures by simultaneous minimization of energy and R factor

1978 • 354 citations

Three-dimensional Structure of Thermolysin

1972 • 292 citations

The Drosophila dorsal-ventral patterning gene tolloid is related to human bone morphogenetic protein 1

1991 • 292 citations

Amino-acid Sequence of Thermolysin

1972 • 251 citations

Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution.

1991 • 201 citations

RIBBON: a stereo cartoon drawing program for proteins

1988 • 190 citations

Three-dimensional structure of the elastase of Pseudomonas aeruginosa at 1.5-A resolution.

1991 • 177 citations

The astacin family of metalloendopeptidases.

1991 • 175 citations

Amino acid sequence of a Crotalus atrox venom metalloproteinase which cleaves type IV collagen and gelatin

1989 • 152 citations

Early mRNAs, spatially restricted along the animal-vegetal axis of sea urchin embryos, include one encoding a protein related to tolloid and BMP-1

1992 • 128 citations

Crystal structure of neutral protease from Bacillus cereus refined at 3.0A˚resolution and comparison with the homologous but more thermostable enzyme thermolysin

1988 • 117 citations

Amino acid sequence of a unique protease from the crayfish Astacus fluviatilis

1987 • 108 citations

Spatial and temporal expression pattern during sea urchin embryogenesis of a gene coding for a protease homologous to the human protein BMP-1 and to the product of the Drosophila dorsal-ventral patterning gene tolloid

1992 • 106 citations

Astacus protease, a zinc metalloenzyme

1988 • 93 citations

Fluorescent oligopeptide substrates for kinetic characterization of the specificity of Astacus protease

1990 • 69 citations

Meprin-A and -B. Cell surface endopeptidases of the mouse kidney.

1991 • 65 citations

Molecular approach to dorsoanterior development in Xenopus laevis

1990 • 56 citations

Types and families of endopeptidases

1991 • 49 citations

Kinetics of Nitroanilide Cleavage by Astacin

1991 • 24 citations