Excitotoxic degeneration is initiated at non-random sites in cultured rat cerebellar neurons

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Excitotoxic cell death

1992 • 2,307 citations

Role of calcium ions in regulation of mammalian intramitochondrial metabolism

1990 • 1,369 citations

Gases as biological messengers: nitric oxide and carbon monoxide in the brain

1994 • 1,052 citations

Digital Image Processing

1991 • 912 citations

Microdomains of High Calcium Concentration in a Presynaptic Terminal

1992 • 837 citations

Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties

1986 • 782 citations

Mitochondrial calcium transport: physiological and pathological relevance

1994 • 702 citations

Inhibition of Mitochondrial Electron Transport by Peroxynitrite

1994 • 697 citations

Fluorescent indicators for cytosolic sodium

1989 • 650 citations

The neurotoxicity of excitatory amino acids is produced by passive chloride influx

1985 • 634 citations

Aconitase is readily inactivated by peroxynitrite, but not by its precursor, nitric oxide.

1994 • 596 citations

Superoxide and peroxynitrite inactivate aconitases, but nitric oxide does not.

1994 • 585 citations

Activity-dependent fluorescent staining and destaining of living vertebrate motor nerve terminals

1992 • 580 citations

Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons

1993 • 569 citations

Bleb Formation in Hepatocytes During Drug Metabolism Is Caused by Disturbances in Thiol and Calcium Ion Homeostasis

1982 • 553 citations

Clustering of L-type Ca2+ channels at the base of major dendrites in hippocampal pyramidal neurons

1990 • 512 citations

Mitochondrial calcium transport

1982 • 486 citations

Calcium entry increases the sensitivity of cerebellar Purkinje cells to applied GABA and decreases inhibitory synaptic currents

1991 • 480 citations

The distribution of glutamate receptors in cultured rat hippocampal neurons: Postsynaptic clustering of AMPA selective subunits

1993 • 340 citations

Acute dendrotoxic changes in the hippocampus of kainate treated rats

1979 • 306 citations

Intracellular calcium concentrations during "chemical hypoxia" and excitotoxic neuronal injury

1991 • 265 citations

“Epileptic” brain damage is replicated qualitatively in the rat hippocampus by central injection of glutamate or aspartate but not by GABA or acetylcholine

1985 • 242 citations

Agonist-activated cobalt uptake identifies divalent cation—Permeable kainate receptors on neurons and glial cells

1991 • 214 citations

The role of cytosolic Ca2+ in cell injury, necrosis and apoptosis

1992 • 199 citations

The calcium cycle of mitochondria

1979 • 197 citations

Regulation of Ion Channel Distribution at Synapses

1993 • 177 citations

Glutamate impairs neuronal calcium extrusion while reducing sodium gradient

1994 • 172 citations

Mechanism of presynaptic inhibition by neuropeptide Y at sympathetic nerve terminals

1993 • 150 citations

Peroxynitrite causes calcium efflux from mitochondria which is prevented by Cyclosporin A

1994 • 143 citations

The Participation of Reactive Oxygen Species and Protein Thiols in the Mechanism of Mitochondrial Inner Membrane Permeabilization by Calcium plus Prooxidants

1993 • 139 citations

Physiological cytosolic Ca2+ transients evoke concurrent mitochondrial depolarizations.

1994 • 139 citations

A model for dendritic Ca2+ accumulation in hippocampal pyramidal neurons based on fluorescence imaging measurements

1994 • 129 citations

Cytosolic ionized calcium and bleb formation after acute cell injury of cultured rabbit renal tubule cells.

1989 • 85 citations

Cytosolic calcium concentrations and cell death in vitro.

1996 • 74 citations

Cell Swelling, Blebbing, and Death Are Dependent on ATP Depletion and Independent of Calcium During Chemical Hypoxia in a Glial Cell Line (ROC‐1)

1992 • 71 citations

Removal of extracellular sodium prevents anoxia-induced injury in freshly dissociated rat CA1 hippocampal neurons

1994 • 69 citations

Intracellular sodium concentration in cultured cerebellar granule cells challenged with glutamate.

1994 • 63 citations

Fluorescence measurements of cytosolic free Na concentration, influx and efflux in gastric cells.

1990 • 60 citations

Glutamate-induced neuronal death in cerebellar culture is mediated by two distinct components: a sodium-chloride component and a calcium component

1994 • 49 citations

Intracellular mitochondrial membrane potential as an indicator of hepatocyte energy metabolism: Further evidence for thermodynamic control of metabolism

1988 • 38 citations

Lipid order in hepatocyte plasma membrane blebs during ATP depletion measured by digitized video fluorescence polarization microscopy

1991 • 36 citations

Excessive intracellular Ca2+ inhibits glutamate-induced Na(+)-K+ pump activation in rat hippocampal neurons

1992 • 32 citations

Changes in both calcium pool size and morphology of human platelets incubated in various concentrations of calcium ion. Calcium-specific bleb formation on platelet-membrane surface

1988 • 20 citations

Characteristics of voltage sensitive calcium channels in dendrites of cultured rat cerebellar neurons

1993 • 19 citations

Oxidative stress, disturbance of energy balance, and death of ascites tumour cells under menadione (vitamin K3) action.

1990 • 12 citations

Removal of calcium overload caused by A23187 is more dependent on glycolysis than oxidative phosphorylation

1993 • 6 citations

Toxic injury from mercuric chloride in rat hepatocytes

1990 • 4 citations