Intracellular mitochondrial membrane potential as an indicator of hepatocyte energy metabolism: Further evidence for thermodynamic control of metabolism

Methods of Enzymatic Analysis

1975 • 20,446 citations

A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid

1956 • 14,202 citations

HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS

1969 • 4,428 citations

Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism

1961 • 4,416 citations

Removal of Fatty Acids from Serum Albumin by Charcoal Treatment

1967 • 2,098 citations

Nonequilibrium Thermodynamics in Biophysics

1965 • 1,704 citations

The Influence of Respiration and ATP Hydrolysis on the Proton‐Electrochemical Gradient across the Inner Membrane of Rat‐Liver Mitochondria as Determined by Ion Distribution

1974 • 707 citations

Biological oxidations

1969 • 499 citations

Factors Influencing the Rates of Long-Chain Fatty Acid Oxidation and Synthesis in Mammalian Systems

1961 • 479 citations

Mechanism of Coupling of Oxidative Phosphorylation and the Membrane Potential of Mitochondria

1969 • 458 citations

Vectorial Chemistry and the Molecular Mechanics of Chemiosmotic Coupling: Power Transmission by Proticity

1976 • 431 citations

Criteria of Viability of Isolated Liver Cells

1975 • 411 citations

Thermodynamics and Control of Biological Free-Energy Transduction

1987 • 403 citations

The value of ΔG° for the hydrolysis of ATP

1972 • 397 citations

Thermodynamics and control of biological free-energy transduction

1988 • 372 citations

Liver Adenine Nucleotides: Fructose-Induced Depletion and Its Effect on Protein Synthesis

1968 • 333 citations

Rapid separation of particulate components and soluble cytoplasm of isolated rat-liver cells

1974 • 324 citations

Regulation of Hepatic Metabolism

1976 • 314 citations

Pyridine nucleotide-dependent dehydrogenases

1971 • 288 citations

Determination of the mitochondrial protonmotive force in isolated hepatocytes.

1980 • 263 citations

Respiratory Control and the Proton Electrochemical Gradient in Mitochondria

1973 • 228 citations

Membrane potential and surface potential in mitochondria: Uptake and binding of lipophilic cations

1984 • 213 citations

Metabolic compartmentation

1983 • 205 citations

Subcellular Metabolite Concentrations

1978 • 182 citations

Energy-linked nicotinamide nucleotide transhydrogenases

1977 • 176 citations

Fully delocalised chemiosmotic or localised proton flow pathways in energy coupling?

1985 • 173 citations

Specific inhibition of mitochondrial fatty acid oxidation by 2-bromopalmitate and its co-enzyme A and carnitine esters

1972 • 172 citations

Acceleration of gluconeogenesis from lactate by lysine (Short Communication)

1973 • 155 citations

31P nuclear magnetic resonance studies of isolated rat liver cells

1978 • 152 citations

Action of the oral hypoglycemic agent 2-tetradecylglycidic acid on hepatic fatty acid oxidation and gluconeogenesis.

1979 • 123 citations

Measurement of the ATP/ADP Ratio in Mitochondria and in the Extramitochondrial Compartment by Fractionation of Freeze-Stopped Liver Tissue in Non-aqueous Media

1974 • 117 citations

The Interaction of Energy and Electron Transfer Reactions in Mitochondria

1961 • 116 citations

Thermodynamic control of electron flux through mitochondrial cytochrome bc1 complex

1985 • 109 citations

A critical assessment of the use of lipophilic cations as membrane potential probes

1984 • 89 citations

The ADP,ATP shuttle of the mitochondrion

1979 • 84 citations

Animal Mitochondria

1958 • 74 citations

[61] High-yield preparation of morphologically intact isolated parenchymal cells from rat liver

1974 • 74 citations

The role of oxidative processes in the cytotoxicity of substituted 1,4-naphthoquinones in isolated hepatocytes

1986 • 70 citations

Use of digitonin fractionation to determine mitochondrial transmembrane ion distribution in cells during anoxia

1985 • 64 citations

The effect of hormones on proton compartmentation in hepatocytes.

1984 • 54 citations

METABOLIC PROPERTIES OF CELLS ISOLATED FROM ADULT MOUSE LIVER

1962 • 54 citations

Regulation of the uncoupling protein in brown adipose tissue.

1986 • 52 citations

Membrane potential of mitochondria in intact lymphocytes during early mitogenic stimulation

1984 • 48 citations

Effects of bicarbonate on intercompartmental reducing-equivalent translocation in isolated parenchymal cells from rat liver

1974 • 43 citations

FINE STRUCTURE OF CELLS ISOLATED FROM ADULT MOUSE LIVER

1962 • 37 citations

Mitochondrial membrane potential monitored in situ within isolated guinea pig brown adipocytes by a styryl pyridinium fluorescent indicator

1984 • 30 citations

Linear relationships between mitochondrial forces and cytoplasmic flows argue for the organized energy‐coupled nature of cellular metabolism

1987 • 26 citations

Base ratio determination using unpurified DNA

1972 • 21 citations

The use of 36Cl− to measure cell plasma membrane potential in isolated hepatocytes — effects of cyclic AMP and bicarbonate ions

1985 • 19 citations

Evidence that stimulation of gluconeogenesis by fatty acid is mediated through thermodynamic mechanisms

1988 • 16 citations

Current-voltage relationships for proton flow through the F0 sector of the ATP-synthase carbonylcyanide-p-trifluoromethoxyphenylhydrazone or leak pathways in submitochondrial particles

1985 • 12 citations

On the role of the membrane proton conductance in the relationship between rate of respiration and protonmotive force

1985 • 4 citations

Introduction

1981 • 3 citations