The role of cytosolic Ca2+ in cell injury, necrosis and apoptosis

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

1991 • 2,127 citations

Apoptosis: Mechanisms and Roles in Pathology

1991 • 1,368 citations

BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.

1991 • 1,301 citations

Chemical and physical carcinogenesis: advances and perspectives for the 1990s.

1991 • 433 citations

Inflammation and Oxidative Stress in Carcinogenesis

1993 • 419 citations

Extracellular ATP as a trigger for apoptosis or programmed cell death.

1991 • 342 citations

Coordinated regulation of apoptosis and cell proliferation by transforming growth factor beta 1 in cultured uterine epithelial cells.

1991 • 279 citations

Drug Metabolism and Drug Toxicity

1985 • 249 citations

T cell receptor/CD3-signaling induces death by apoptosis in human T cell receptor gamma delta + T cells.

1991 • 167 citations

Induction of apoptosis during normal and neoplastic B-cell development in the bursa of Fabricius.

1991 • 153 citations

Cytolytic lymphocytes induce both apoptosis and necrosis in target cells.

1991 • 145 citations

Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions.

1990 • 119 citations

Toxic injury from mercuric chloride in rat hepatocytes.

1990 • 108 citations

Cytochalasin B induces cellular DNA fragmentation

1990 • 93 citations

Calcium signals and cancer.

1992 • 90 citations

Regulation of c-fos and c-jun protooncogene expression by the Ca(2+)-ATPase inhibitor thapsigargin.

1991 • 83 citations

NK cell‐induced cytotoxicity is dependent on a Ca²⁺ increase in the target

1990 • 73 citations

Quantitative analysis of adenine nucleotides during the prelytic phase of cell death mediated by C5b-9.

1991 • 64 citations

Cytosolic Ca2+ deregulation and blebbing after HgCl2 injury to cultured rabbit proximal tubule cells as determined by digital imaging microscopy.

1991 • 48 citations

HgCl2-induced alteration of actin filaments in cultured primary rat proximal tubule epithelial cells labelled with fluorescein phalloidin

1991 • 46 citations

Macrophage activation for intracellular killing as induced by calcium ionophore. Correlation with biologic and biochemical events.

1991 • 41 citations

Oxidative Injury Induces Influx-Dependent Changes in Intracellular Calcium Homeostasis

1991 • 38 citations

Epidermal growth factor-stimulated calcium ion transients in individual A431 cells: initiation kinetics and ligand concentration dependence.

1991 • 31 citations

Differences in the regulation of intracellular calcium in normal and neoplastic keratinocytes are not caused by ras gene mutations.

1991 • 25 citations

Calcium-dependent natural killer and calcium-independent natural cytotoxic activities in an IL-2-dependent killer cell line.

1990 • 18 citations

Relation Between Toxicity and Carcinogenesis in the Kidney: an Heuristic Hypothesis

1990 • 5 citations