Fatty Acid Binding Proteins—The Evolutionary Crossroads of Inflammatory and Metabolic Responses

Atherosclerosis — An Inflammatory Disease

1999 • 21,494 citations

Insulin signalling and the regulation of glucose and lipid metabolism

2001 • 4,995 citations

Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology

2001 • 3,629 citations

The peroxisome proliferator-activated receptor-γ is a negative regulator of macrophage activation

1998 • 3,517 citations

A central role for JNK in obesity and insulin resistance

2002 • 3,225 citations

Atherosclerosis

2001 • 2,982 citations

mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer.

1994 • 2,176 citations

Nuclear Receptors and Lipid Physiology: Opening the X-Files

2001 • 2,040 citations

Free fatty acids regulate insulin secretion from pancreatic β cells through GPR40

2003 • 1,469 citations

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IκB kinase

2000 • 1,337 citations

Insulin resistance and cardiovascular disease

2000 • 1,280 citations

Reciprocal regulation of inflammation and lipid metabolism by liver X receptors

2003 • 1,075 citations

15-Deoxy-Δ ^12,14 -prostaglandin J ₂ inhibits multiple steps in the NF-κB signaling pathway

2000 • 1,014 citations

Improvement in Glucose Tolerance and Insulin Resistance in Obese Subjects Treated with Troglitazone

1994 • 935 citations

Uncoupling of Obesity from Insulin Resistance Through a Targeted Mutation in aP2 , the Adipocyte Fatty Acid Binding Protein

1996 • 900 citations

Peroxisome proliferator–activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor–deficient mice

2000 • 846 citations

Serine Phosphorylation of Insulin Receptor Substrate 1 by Inhibitor κB Kinase Complex

2002 • 742 citations

Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes

2001 • 733 citations

Prevention of fat-induced insulin resistance by salicylate

2001 • 713 citations

Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes

2001 • 692 citations

Lack of macrophage fatty-acid–binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis

2001 • 674 citations

PPARγ, the ultimate thrifty gene

1999 • 609 citations

New insights into the structure and function of fatty acid-binding proteins

2002 • 515 citations

Preadipocyte Conversion to Macrophage

2003 • 508 citations

Function of GATA Transcription Factors in Preadipocyte-Adipocyte Transition

2000 • 496 citations

Selective Cooperation between Fatty Acid Binding Proteins and Peroxisome Proliferator-Activated Receptors in Regulating Transcription

2002 • 487 citations

Fatty acids and hypolipidemic drugs regulate peroxisome proliferator-activated receptors α- and γ-mediated gene expression via liver fatty acid binding protein: A signaling path to the nucleus

2001 • 485 citations

Dietary polyunsaturated fatty acids and regulation of gene transcription

2002 • 426 citations

15-Deoxy-Δ12,14-prostaglandin J2

2002 • 393 citations

Physiological properties and functions of intracellular fatty acid-binding proteins

1998 • 325 citations

A role for preadipocytes as macrophage‐like cells

1999 • 319 citations

A molecular aspect of hematopoiesis and endoderm development common to vertebrates and Drosophila

1996 • 310 citations

Improved Glucose and Lipid Metabolism in Genetically Obese Mice Lacking aP2

2000 • 304 citations

Requirement for the heart‐type fatty acid binding protein in cardiac fatty acid utilization

1999 • 303 citations

15-Deoxy-Δ12,14-prostaglandin J2Inhibition of NF-κB-DNA Binding through Covalent Modification of the p50 Subunit

2001 • 297 citations

Peroxisome Proliferator-Activated Receptor-γ Agonist 15-Deoxy-Δ12,1412,14-Prostaglandin J2 Ameliorates Experimental Autoimmune Encephalomyelitis

2002 • 292 citations

Targeted disruption of the adipocyte lipid-binding protein (aP2 protein) gene impairs fat cell lipolysis and increases cellular fatty acid levels

1999 • 288 citations

Membrane proteins implicated in long-chain fatty acid uptake by mammalian cells: CD36, FATP and FABPm

1999 • 266 citations

Role of the Fatty Acid Binding Protein mal1 in Obesity and Insulin Resistance

2003 • 219 citations

Role of PPARs in the regulation of obesity-related insulin sensitivity and inflammation

2003 • 208 citations

Altered insulin secretion associated with reduced lipolytic efficiency in aP2-/- mice.

1999 • 205 citations

Impaired Long-Chain Fatty Acid Utilization by Cardiac Myocytes Isolated From Mice Lacking the Heart-Type Fatty Acid Binding Protein Gene

1999 • 203 citations

The adipocyte lipid binding protein (ALBP/aP2) gene facilitates foam cell formation in human THP-1 macrophages

2002 • 183 citations

Decreased Liver Fatty Acid Binding Capacity and Altered Liver Lipid Distribution in Mice Lacking the Liver Fatty Acid-binding Protein Gene

2003 • 180 citations

PPARγ Activation Induces the Expression of the Adipocyte Fatty Acid Binding Protein Gene in Human Monocytes

1999 • 180 citations

The intestinal fatty acid binding protein is not essential for dietary fat absorption in mice

2000 • 179 citations

Adipocyte Fatty Acid–Binding Protein, aP2, Alters Late Atherosclerotic Lesion Formation in Severe Hypercholesterolemia

2002 • 170 citations

Different genes, different diabetes: lessons from maturity-onset diabetes of the young

2002 • 163 citations

Oxidized LDL induces the expression of ALBP/aP2 mRNA and protein in human THP-1 macrophages

2000 • 134 citations

Protein Kinase C and Lipid‐Induced Insulin Resistance in Skeletal Muscle

2002 • 121 citations

Series Introduction: The molecular and physiological basis of insulin resistance: emerging implications for metabolic and cardiovascular diseases

2000 • 119 citations

Lipid-binding proteins modulate ligand-dependent trans-activation by peroxisome proliferator-activated receptors and localize to the nucleus as well as the cytoplasm

2000 • 115 citations

Characterization of the Functional Interaction of Adipocyte Lipid-binding Protein with Hormone-sensitive Lipase

2001 • 86 citations

Analysis on the phenotype of E-FABP-gene knockout mice.

2002 • 69 citations

Differential influence of rat liver fatty acid binding protein isoforms on phospholipid fatty acid composition: phosphatidic acid biosynthesis and phospholipid fatty acid remodeling

1998 • 54 citations

SREBP-1: Gene Regulatory Key to Syndrome X?

2002 • 31 citations