Bacterial Lipopolysaccharide Enhances Chemoattractant-Induced Elastase Secretion by Human Neutrophils

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Role of oxygen-derived free radicals and metabolites in leukocyte-dependent inflammatory reactions.

1982 • 1,241 citations

Oxygen radicals mediate endothelial cell damage by complement-stimulated granulocytes. An in vitro model of immune vascular damage.

1978 • 1,117 citations

Modulation of multiple neutrophil functions by preparative methods or trace concentrations of bacterial lipopolysaccharide.

1985 • 796 citations

Rapid Charcoal Assay for Intrinsic Factor (IF), Gastric Juice Unsaturated B12 Binding Capacity, Antibody to IF, and Serum Unsaturated B12 Binding Capacity

1965 • 743 citations

The effects of bacterial endotoxins on host mediation systems. A review.

1978 • 648 citations

Priming of neutrophils for enhanced release of oxygen metabolites by bacterial lipopolysaccharide. Evidence for increased activity of the superoxide-producing enzyme.

1984 • 612 citations

Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells.

1981 • 587 citations

Neutrophil-mediated injury to endothelial cells. Enhancement by endotoxin and essential role of neutrophil elastase.

1986 • 576 citations

Elastolytic Activity in Pulmonary Lavage Fluid from Patients with Adult Respiratory-Distress Syndrome

1981 • 528 citations

Neutrophil-mediated endothelial injury in vitro mechanisms of cell detachment.

1981 • 446 citations

Activation of the Classical and Properdin Pathways of Complement by Bacterial Lipopolysaccharides (LPS)

1977 • 425 citations

In vivo damage of rat lungs by oxygen metabolites.

1981 • 360 citations

Studies on the Pathogenesis of the Adult Respiratory Distress Syndrome

1982 • 359 citations

Secretory Responses of Human Neutrophils: Exocytosis of Specific (Secondary) Granules by Human Neutrophils during Adherence in vitro and during Exudation in vivo

1979 • 286 citations

Intracellular control of human neutrophil secretion. I. C5a-induced stimulus-specific desensitization and the effects of cytochalasin B.

1978 • 283 citations

Degradation of type IV (basement membrane) collagen by a proteinase isolated from human polymorphonuclear leukocyte granules.

1980 • 279 citations

Biological effects of the human complement fragments C5a and C5ades Arg on neutrophil function

1980 • 265 citations

Mouse macrophage elastase. Purification and characterization as a metalloproteinase

1981 • 260 citations

The Microbicidal Mechanisms of Human Neutrophils and Eosinophils

1981 • 259 citations

INTERACTION OF CELLS WITH IMMUNE COMPLEXES: ADHERENCE, RELEASE OF CONSTITUENTS, AND TISSUE INJURY

1971 • 255 citations

The immunologic release of constituents from neutrophil leukocytes. II. Mechanisms of release during phagocytosis, and adherence to nonphagocytosable surfaces.

1971 • 246 citations

Cytochalasin B: Effect on Lysosomal Enzyme Release from Human Leukocytes

1973 • 243 citations

The sequential release of granule constitutents from human neutrophils.

1980 • 232 citations

Neutrophil-mediated Pulmonary Vascular Injury: Synergistic Effect of Trace Amounts of Lipopolysaccharide and Neutrophil Stimuli on Vascular Permeability and Neutrophil Sequestration in the Lung

1987 • 228 citations

Leukocytic proteases and the immunologic release of lysosomal enzymes.

1972 • 197 citations

Lung injury induced by leukocytic proteases.

1979 • 183 citations

PATHOGENIC FACTORS IN VASCULAR LESIONS OF EXPERIMENTAL SERUM SICKNESS

1965 • 172 citations

Glomerular basement membrane damage in immunological glomerulonephritis.

1968 • 145 citations

Granulocyte activation by endotoxin. I. Correlation between adherence and other granulocyte functions, and role of endotoxin structure on biologic activity.

1983 • 145 citations

Role of microtubule assembly in lysosomal enzyme secretion from human polymorphonuclear leukocytes. A reevaluation.

1977 • 142 citations

Human neutrophil elastase functions as a type III collagen “Collagenase”

1980 • 137 citations

Chemical structure and biological activities of lipid A's from various bacterial families

1978 • 136 citations

The differential mobilization of human neutrophil granules. Effects of phorbol myristate acetate and ionophore A23187.

1977 • 136 citations

Differences in the ingestion mechanisms of IgG and C3b particles in phagocytosis by neutrophils.

1982 • 129 citations

Activated neutrophils disrupt endothelial monolayer integrity by an oxygen radical-independent mechanism.

1985 • 122 citations

Neutrophil specific granules: a fuse that ignites the inflammatory response.

1984 • 96 citations

Polymorphonuclear leukocyte migration through human amnion membrane

1981 • 83 citations

Enhancement of Immunologically Induced Granule Exocytosis from Neutrophils by Cytochalasin B

1973 • 74 citations

Localization of Chymotrypsin-Like Cationic Protein, Collagenase and Elastase in Azurophil Granules of Human Neutrophilic Polymorphonuclear Leukocytes

1977 • 69 citations

Molecular requirement for interleukin 1 induction by lipopolysaccharide‐stimulated human monocytes: Involvement of the heptosyl‐2‐keto 3‐deoxyoctulosonate region

1986 • 65 citations

Granulocyte activation by endotoxin. II. Role of granulocyte adherence, aggregation, and effect of cytochalasin B, and comparison with formylated chemotactic peptide-induced stimulation.

1983 • 65 citations

Lipopolysaccharide from Escherichia coli. Heterogeneity and mechanism of reversible inactivation by sodium deoxycholate

1969 • 52 citations

The secretory code of the neutrophil.

1979 • 51 citations

Elastase-like enzymes in human neutrophils localized by ultrastructural cytochemistry.

1980 • 47 citations

Release of Granulocyte Elastase in Lethal Canine Endotoxin Shock

1978 • 40 citations

Further studies on an esterase inhibitor in human leukocyte cytosol.

1971 • 19 citations

Immunologic properties of protein-lipopolysaccharide complexes—III

1980 • 18 citations

Hydrogen Peroxide Causes Permeability Edema and Hypertension in Isolated Salt-Perfused Rabbit Lungs

1983 • 11 citations