Studies on the Pathogenesis of the Adult Respiratory Distress Syndrome

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Morphometry of the Human Lung

2013 • 2,486 citations

Plasminogen: Purification from Human Plasma by Affinity Chromatography

1970 • 2,160 citations

A Method of Trace Iodination of Proteins for Immunologic Studies

1966 • 2,148 citations

Morphometry of the Human Lung

1963 • 1,950 citations

Complement and Leukocyte-Mediated Pulmonary Dysfunction in Hemodialysis

1977 • 1,014 citations

Analysis of cellular and protein content of broncho-alveolar lavage fluid from patients with idiopathic pulmonary fibrosis and chronic hypersensitivity pneumonitis.

1977 • 570 citations

Human leukocyte granule elastase: rapid isolation and characterization

1976 • 550 citations

Elastolytic Activity in Pulmonary Lavage Fluid from Patients with Adult Respiratory-Distress Syndrome

1981 • 528 citations

Morphology of the bronchial tree in man.

1968 • 475 citations

MEDIATORS OF INFLAMMATION IN LEUKOCYTE LYSOSOMES

1968 • 456 citations

Cigarette Smoking Induces Functional Antiprotease Deficiency in the Lower Respiratory Tract of Humans

1979 • 398 citations

Possible mechanisms of emphysema in smokers. In vitro suppression of serum elastase-inhibitory capacity by fresh cigarette smoke and its prevention by antioxidants.

1978 • 364 citations

In vivo damage of rat lungs by oxygen metabolites.

1981 • 360 citations

Selective oxidation of methionine residues in proteins

1975 • 346 citations

Human Granulocyte Collagenase

1968 • 335 citations

The Induction of Pulmonary Emphysema with Human Leukocyte Elastase^1–3

1977 • 335 citations

Respiratory Function in Disease.

1972 • 301 citations

Experimental emphysema induced with purified human neutrophil elastase: tissue localization of the instilled protease.

1977 • 284 citations

Enzymatic inactivation of human alpha-1-proteinase inhibitor by neutrophil myeloperoxidase

1979 • 270 citations

POLYMORPHONUCLEAR LEUKOCYTES IN IMMUNOLOGIC REACTIONS

1966 • 266 citations

Structural evidence for methionine at the reactive site of human alpha-1-proteinase inhibitor.

1978 • 264 citations

DIRECT EVIDENCE FOR HAGEMAN FACTOR (FACTOR XII) ACTIVATION BY BACTERIAL LIPOPOLYSACCHARIDES (ENDOTOXINS)

1974 • 259 citations

Intravascular coagulation associated with the adult respiratory distress syndrome

1976 • 254 citations

C5 Chemotactic Fragments Produced by an Enzyme in Lysosomal Granules of Neutrophils

1970 • 246 citations

Human high molecular weight kininogen. Studies of structure-function relationships and of proteolysis of the molecule occurring during contact activation of plasma.

1979 • 230 citations

Activation of hageman factor by collagen

1968 • 221 citations

Cigarette Smoke Inhalation Decreases α ₁ -Antitrypsin Activity in Rat Lung

1979 • 206 citations

Cryoprecipitate Reversal of Opsonic α ₂ -Surface Binding Glycoprotein Deficiency in Septic Surgical and Trauma Patients

1978 • 196 citations

Interaction of human .alpha.-1-proteinase inhibitor with neutrophil myeloperoxidase

1981 • 119 citations

Documentation of pulmonary capillary permeability in the adult respiratory distress syndrome accompanying human sepsis.

1979 • 119 citations

[7] Human factor XII (Hageman factor)

1976 • 117 citations

Proteases from purulent sputum. Purification and properties of the elastase and chymotrypsin-like enzymes.

1977 • 116 citations

Mediators of tissue damage in leukocyte lysosomes. X. Further studies on human granulocyte elastase.

1970 • 103 citations

Studies on the Adsorption and Activation of the Hageman Factor (Factor XII) by Collagen and Elastin

1965 • 91 citations

Activation of Rabbit Hageman Factor by Homogenates of Cultured Rabbit Endothelial Cells

1980 • 74 citations

The role of fibrinogen degradation products in the pathogenesis of the respiratory distress syndrome.

1977 • 74 citations

Elevated fibrin(ogen) degradation products in the adult respiratory distress syndrome.

1980 • 71 citations

Molecular assembly in the contact phase of the Hageman factor system

1979 • 70 citations

Elastase and lysozyme activities in human alveolar macrophages. Effects of cigarette smoking.

1980 • 69 citations

Studies on the elastase-serum protein interaction

1967 • 65 citations

The effects in vivo and in vitro of oxidative damage to purified alpha1-antitrypsin and to the enzyme-inhibiting activity of plasma.

1979 • 57 citations

Digestion of Lung Proteins by Human Leukocyte Granules in Vitro

1972 • 36 citations

Partial purification and characterization of mouse peritoneal exudative macrophage elastase

1980 • 35 citations

Effect of oxidation of methionine residues in chicken ovoinhibitor on its inhibitory activities against trypsin, chymotrypsin, and elastase

1977 • 31 citations

Adsorption of hageman factor (factor XII) on collagen

1964 • 26 citations

Conference report: Mechanisms of acute respiratory failure.

1977 • 20 citations

Molecular assembly in the contact phase of the Hageman factor system

1979 • 7 citations

Permeability Pulmonary Edema

2008 • 4 citations