Biological effects of the human complement fragments C5a and C5ades Arg on neutrophil function

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The Reliability of Molecular Weight Determinations by Dodecyl Sulfate-Polyacrylamide Gel Electrophoresis

1969 • 20,498 citations

Disk Electrophoresis of Basic Proteins and Peptides on Polyacrylamide Gels

1962 • 2,951 citations

A simplified method for cyanogen bromide activation of agarose for affinity chromatography

1974 • 1,951 citations

LEUKOCYTE LOCOMOTION AND CHEMOTAXIS

1973 • 1,709 citations

Proteases and biological control

1976 • 1,380 citations

Complement and immunoglobulins stimulate superoxide production by human leukocytes independently of phagocytosis.

1975 • 749 citations

The role of superoxide anion generation in phagocytic bactericidal activity. Studies with normal and chronic granulomatous disease leukocytes.

1975 • 705 citations

Chemotactic response to human C3a and C5a anaphylatoxins. I. Evaluation of C3a and C5a leukotaxis in vitro and under stimulated in vivo conditions.

1978 • 567 citations

The immunologic release of constituents from neutrophil leukocytes. I. The role of antibody and complement on nonphagocytosable surfaces or phagocytosable particles.

1971 • 513 citations

Demonstration of specific C5a receptor on intact human polymorphonuclear leukocytes.

1978 • 512 citations

Anaphylatoxin inactivator of human plasma: its isolation and characterization as a carboxypeptidase

1970 • 509 citations

THE DERIVATION OF TWO DISTINCT ANAPHYLATOXIN ACTIVITIES FROM THE THIRD AND FIFTH COMPONENTS OF HUMAN COMPLEMENT

1968 • 460 citations

THE ROLE OF SERUM COMPLEMENT IN CHEMOTAXIS OF LEUKOCYTES IN VITRO

1965 • 404 citations

Chemotactic Response to Human C3a and C5a Anaphylatoxins

1978 • 393 citations

Mechanisms of Lysosomal Enzyme Release from Human Leukocytes: Microtubule Assembly and Membrane Fusion Induced by a Component of Complement

1973 • 329 citations

The Immunologic Release of Constituents from Neutrophil Leukocytes

1971 • 319 citations

Intracellular control of human neutrophil secretion. I. C5a-induced stimulus-specific desensitization and the effects of cytochalasin B.

1978 • 283 citations

Stimulation of neutrophil oxidative metabolism by chemotactic peptides: influence of calcium ion concentration and cytochalasin B and comparison with stimulation by phorbol myristate acetate

1979 • 259 citations

Primary structural analysis of the polypeptide portion of human C5a anaphylatoxin. Polypeptide sequence determination and assignment of the oligosaccharide attachment site in C5a.

1978 • 253 citations

THE DEACTIVATION OF RABBIT NEUTROPHILS BY CHEMOTACTIC FACTOR AND THE NATURE OF THE ACTIVATABLE ESTERASE

1968 • 244 citations

The ability of chemotactic factors to induce lysosomal enzyme release. I. The characteristics of the release, the importance of surfaces and the relation of enzyme release to chemotactic responsiveness.

1974 • 212 citations

FORMATION OF C3a AND C5a ANAPHYLATOXINS IN WHOLE HUMAN SERUM AFTER INHIBITION OF THE ANAPHYLATOXIN INACTIVATOR

1973 • 204 citations

In Vitro Studies of Immunologically Induced Secretion of Mediators from Cells and Related Phenomena

1973 • 202 citations

Lysosomal Enzyme Release from Human Leukocytes: Mediation by the Alternate Pathway of Complement Activation

1973 • 188 citations

Partial characterization of human C5a anaphylatoxin. I. Chemical description of the carbohydrate and polypeptide prtions of human C5a.

1976 • 185 citations

BIOLOGICAL ACTIVITY OF COMPLEMENT IN VIVO

1971 • 185 citations

Superoxide production induced in rabbit polymorphonuclear leukocytes by synthetic chemotactic peptides and A23187.

1979 • 158 citations

Stimulation of human neutrophil leukocyte aerobic glucose metabolism by purified chemotactic factors.

1974 • 158 citations

Intracellular Control of Human Neutrophil Secretion

1978 • 155 citations

A modified method for chemotaxis under agarose

1979 • 131 citations

Complement fragments, alveolar macrophages, and alveolitis.

1979 • 129 citations

The Ability of Chemotactic Factors to Induce Lysosomal Enzyme Release

1974 • 128 citations

A Chemotactic Factor for Mononuclear Leukocytes

1971 • 116 citations

Partial Characterization of Human C5a Anaphylatoxin

1976 • 104 citations

Induction of Lysosomal Enzyme Secretion by Alveolar Macrophages in Response to the Purified Complement Fragments C5a and C5a des-arg

1979 • 87 citations

Studies on the regulation of the neutrophil chemotactic response using a rapid and reliable method for measuring random migration and chemotaxis of neutrophil granulocytes

1976 • 79 citations

Enhancement of Immunologically Induced Granule Exocytosis from Neutrophils by Cytochalasin B

1973 • 74 citations

Polymorphonuclear leukocyte and monocyte chemoattractants produced by human fibroblasts.

1979 • 63 citations

Rapid micromeasurement of neutrophil exocytosis

1978 • 45 citations

Chemotactic factor for tumor cells derived from the C5a fragment of complement component C5.

1979 • 38 citations

Chemotactic activity of C5ades Arg: Evidence of a requirement for an anionic peptide ‘helper factor’ and inhibition by a cationic protein in serum from patients with systemic lupus erythematosus

1980 • 35 citations

Chemistry and biology of the anaphylatoxin related serum peptide system. III. Evaluation of leucotactic activity as a property of a new peptide system with classical anaphylatoxin and cocytotaxin as components

1972 • 31 citations

2 Carboxypeptidase B

1971 • 19 citations

Initial Characterization of the Human Polymorphonuclear Leukocyte (PMN) C5a Receptor

1978 • 11 citations