Cross-Presentation of HLA Class I Epitopes from Exogenous NY-ESO-1 Polypeptides by Nonprofessional APCs

A testicular antigen aberrantly expressed in human cancers detected by autologous antibody screening

1997 • 1,235 citations

A Phagosome-to-Cytosol Pathway for Exogenous Antigens Presented on MHC Class I Molecules

1995 • 882 citations

Interaction of Heat Shock Proteins with Peptides and Antigen Presenting Cells: Chaperoning of the Innate and Adaptive Immune Responses

2002 • 845 citations

Simultaneous Humoral and Cellular Immune Response against Cancer–Testis Antigen NY-ESO-1: Definition of Human Histocompatibility Leukocyte Antigen (HLA)-A2–binding Peptide Epitopes

1998 • 728 citations

A Survey of the Humoral Immune Response of Cancer Patients to a Panel of Human Tumor Antigens

1998 • 712 citations

Specific T Helper Cell Requirement for Optimal Induction of Cytotoxic T Lymphocytes against Major Histocompatibility Complex Class II Negative Tumors

1998 • 611 citations

Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells.

1982 • 576 citations

Cross-presentation in viral immunity and self-tolerance

2001 • 460 citations

Induction of primary NY-ESO-1 immunity: CD8+ T lymphocyte and antibody responses in peptide-vaccinated patients with NY-ESO-1+ cancers

2000 • 435 citations

Established Human Papillomavirus Type 16-Expressing Tumors Are Effectively Eradicated Following Vaccination with Long Peptides

2002 • 410 citations

Monitoring CD8 T cell responses to NY-ESO-1: Correlation of humoral and cellular immune responses

2000 • 407 citations

Lactacystin and clasto-Lactacystin β-Lactone Modify Multiple Proteasome β-Subunits and Inhibit Intracellular Protein Degradation and Major Histocompatibility Complex Class I Antigen Presentation

1997 • 388 citations

The cell biology of antigen presentation in dendritic cells

2001 • 375 citations

Identification of Ny-Eso-1 Epitopes Presented by Human Histocompatibility Antigen (Hla)-Drb4*0101–0103 and Recognized by Cd4+T Lymphocytes of Patients with Ny-Eso-1–Expressing Melanoma

2000 • 232 citations

CD4⁺T cell recognition of MHC class II-restricted epitopes from NY-ESO-1 presented by a prevalent HLA DP4 allele: Association with NY-ESO-1 antibody production

2001 • 199 citations

A mutant p53 tumor suppressor protein is a target for peptide-induced CD8+ cytotoxic T-cells.

1993 • 171 citations

Proteasome-Assisted Identification of a SSX-2-Derived Epitope Recognized by Tumor-Reactive CTL Infiltrating Metastatic Melanoma

2002 • 127 citations

Generation of Human Cytolytic T Lymphocyte Lines Directed Against Prostate-Specific Antigen (PSA) Employing a PSA Oligoepitope Peptide

1998 • 126 citations

Generation of NY-ESO-1-specific CD4+ and CD8+ T cells by a single peptide with dual MHC class I and class II specificities: a new strategy for vaccine design.

2002 • 117 citations

NY-ESO-1 119-143 is a promiscuous major histocompatibility complex class II T-helper epitope recognized by Th1- and Th2-type tumor-reactive CD4+ T cells.

2002 • 115 citations

Strategy for monitoring T cell responses to NY-ESO-1 in patients with any HLA class I allele

2000 • 108 citations

In vitro activity of CD4+ and CD8+ T lymphocytes from mice immunized with a synthetic malaria peptide.

1991 • 90 citations

Differential presentation of a soluble exogenous tumor antigen, NY-ESO-1, by distinct human dendritic cell populations

2002 • 88 citations

CD8⁺T cell responses against a dominant cryptic HLA-A2 epitope after NY-ESO-1 peptide immunization of cancer patients

2002 • 83 citations

The specificity of proteasomes: impact on MHC class I processing and presentation of antigens

1999 • 76 citations

The protease inhibitor, N-acetyl-L-leucyl-L-leucyl-leucyl-L-norleucinal, decreases the pool of major histocompatibility complex class I-binding peptides and inhibits peptide trimming in the endoplasmic reticulum.

1996 • 63 citations

Exogenous Peptides Presented by Transporter Associated with Antigen Processing (TAP)-Deficient and TAP-Competent Cells: Intracellular Loading and Kinetics of Presentation

2001 • 59 citations

A simple and efficient method for the monitoring of antigen-specific T cell responses using peptide pool arrays in a modified ELISpot assay

2001 • 55 citations

Cytotoxic T cell polyepitope vaccines delivered by ISCOMs

2001 • 48 citations

Immunization of BALB/c mice with recombinant simian virus 40 large tumor antigen induces antibody-dependent cell-mediated cytotoxicity against simian virus 40-transformed cells. An antibody-based mechanism for tumor immunity.

1994 • 45 citations

Extracellular processing and presentation of a 69-mer synthetic polypeptide to MHC class I-restricted T cells

1999 • 34 citations