Snake Venoms and Blood Coagulation

Purification and properties

1975 • 1,733 citations

Personal communication

2024 • 1,688 citations

The Purification and Mechanism of Action of Human Antithrombin-Heparin Cofactor

1973 • 1,363 citations

MTP international review of science

1973 • 761 citations

Vitamin K Dependent Modifications of Glutamic Acid Residues in Prothrombin

1974 • 750 citations

A new vitamin K-dependent protein. Purification from bovine plasma and preliminary characterization.

1976 • 634 citations

The Mode of Action of Vitamin K

1974 • 527 citations

Human Blood Coagulation, Haemostasis and Thrombosis.

1973 • 426 citations

Gifttiere und ihre Waffen

1986 • 391 citations

Basic Mechanisms in Blood Coagulation

1975 • 366 citations

ACTIVATION OF HAGEMAN FACTOR IN SOLID AND FLUID PHASES

1973 • 346 citations

On the Solubility of Fibrin Clots

1948 • 331 citations

Williams trait. Human kininogen deficiency with diminished levels of plasminogen proactivator and prekallikrein associated with abnormalities of the Hageman factor-dependent pathways.

1975 • 324 citations

Actions of Thrombin and Other Coagulant and Proteolytic Enzymes on Blood Platelets

1967 • 314 citations

Primary structure of the vitamin K-dependent part of prothrombin

1974 • 289 citations

Treatment of Deep Vein Thrombosis. A Trial of Heparin, Streptokinase, and Arvin

1969 • 257 citations

Platelets and Thrombosis

1968 • 233 citations

The Dynamics of Living Protoplasm

1956 • 233 citations

Fibrinogenolytic enzymes of Trimeresurus mucrosquamatus venom

1976 • 231 citations

Recent Advances in Blood Coagulation

1970 • 228 citations

The Fibrinogen-Fibrin Conversion

1957 • 223 citations

A pre-albumin activator of prekallikrein.

1970 • 222 citations

Activation and control of factor VII by activated factor X and thrombin. Isolation and characterization of a single chain form of factor VII

1975 • 215 citations

The coagulation of blood

1908 • 214 citations

Thrombosis and Bleeding Disorders

1971 • 212 citations

PROLONGED COAGULATION DEFECT (DEFIBRINATION SYNDROME) IN MALAYAN VIPER BITE

1963 • 211 citations

The Physiology of Blood Platelets.

1965 • 210 citations

The Isolation and Properties of the Thrombin‐like Activity from Ancistrodon rhodostoma Venom

1967 • 205 citations

Mechanism of activation of bovine factor IX (Christmas factor) by bovine factor XIa(activated plasma thromboplastin antecedent)

1974 • 197 citations

FACTORS WHICH INFLUENCE THE ACTIVITY OF PURIFIED THROMBIN

1942 • 197 citations

THE HEMORRHAGIC DISEASES

1958 • 191 citations

THERAPEUTIC DEFIBRINATION IN THE TREATMENT OF THROMBOTIC DISEASE

1968 • 191 citations

Bovine factor X₁ (Stuart factor). Mechanism of activation by a protein from Russell's viper venom

1972 • 175 citations

THE MOLECULAR STRUCTURE OF FIBRINOGEN

1972 • 174 citations

The isolation and purification of a bovine-plasma protein which is a substrate for the coagulant fraction of Russell's-viper venom

1962 • 170 citations

A Pre-Albumin Activator of Prekallikrein

1970 • 169 citations

Blood clotting enzymology

1968 • 169 citations

Human Blood Coagulation

1969 • 169 citations

Prothrombin activation induced by ecarin - A prothrombin converting enzyme from echis carinatus venom

1975 • 166 citations

The Reaction between Bovine Brain Tissue Factor and Factors VII and X^*

1966 • 165 citations

The Inhibition of Human Plasmin by Human Antithrombin-Heparin Cofactor

1974 • 163 citations

Purification and Properties of a Thrombin-like Enzyme from the Venom of Crotalus adamanteus (Eastern Diamondback Rattlesnake)

1971 • 161 citations

Platelet Interaction with Polymerizing Fibrin

1972 • 161 citations

SYNDROMES OF DISSEMINATED INTRAVASCULAR COAGULATION

1966 • 155 citations

Vitamin K and the Biosynthesis of Prothrombin

1972 • 146 citations

THE FIBRINOLYTIC PATHWAY OF HUMAN PLASMA

1972 • 144 citations

Thrombosthenin, the Contractile Protein from Blood Platelets and Its Relation to other Contractile Proteins

1965 • 143 citations

The fractionation of Russell's-viper (Vipera russellii) venom with special reference to the coagulant protein

1962 • 142 citations

THE COAGULATION OF BLOOD BY SNAKE VENOMS AND ITS PHYSIOLOGIC SIGNIFICANCE

1937 • 140 citations

Snake Venom Poisoning in the United States

1975 • 139 citations

SOME PROTEOLYTIC ACTIVITIES OF SNAKE VENOMS

1955 • 138 citations

Studies on a procoagulant fraction of southern copperhead snake venom: the preferential release of fibrinopeptide B.

1970 • 136 citations

PLATELET EXTRACTS, FIBRIN FORMATION AND INTERACTION OF PURIFIED PROTHROMBIN AND THROMBOPLASTIN

1948 • 135 citations

Separation from Russell's viper venom of one fraction reacting with factor X and another reacting with factor V

1969 • 134 citations

Activation of Purified Prothrombin to Autoprothrombin I or Autoprothrombin II (Platelet Cofactor II or Autoprothrombin II-A)

1961 • 131 citations

ANTICOAGULANT THERAPY WITH A PURIFIED FRACTION OF MALAYAN PIT VIPER VENOM

1968 • 130 citations

Mode of action of vitamin K. Calcium binding properties of bovine prothrombin

1972 • 128 citations

Coagulant and anticoagulant action of snake venoms

1969 • 127 citations

The dynamics of living protoplasm

1956 • 127 citations

Reptilase®‐R—A New Reagent in Blood Coagulation

1971 • 125 citations

A STUDY ON THE CONVERSION OF FIBRINOGEN TO FIBRIN

1944 • 125 citations

The Conversion of Prothrombin to Thrombin

1974 • 124 citations

The Conversion of Prothrombin to Thrombin

1974 • 124 citations

SOME PROPERTIES OF PURIFIED PROTHROMBIN AND ITS ACTIVATION WITH SODIUM CITRATE

1950 • 123 citations

The Specific Assay of Prothrombin Using the Taipan Snake Venom

1971 • 123 citations

On the Significance of the Release of Two Different Peptides from Fibrinogen During Clotting.

1958 • 121 citations

STUDIES OF THE PLASMIN SYSTEM

1958 • 120 citations

Snake Venom Poisoning in the United States

1980 • 120 citations

The Diagnosis of Bleeding Disorders.

1975 • 118 citations

SERUM AC-GLOBULIN: FORMATION FROM PLASMA AC-GLOBULIN; ROLE IN BLOOD COAGULATION; PARTIAL PURIFICATION; PROPERTIES; AND QUANTITATIVE DETERMINATION

1948 • 117 citations

CLINICAL EFFECTS OF BITES BY MALAYAN VIPER (ANCISTRODON RHODOSTOMA)

1963 • 117 citations

Biophysical mechanisms in vascular homeostasis and intravascular thrombosis

1966 • 113 citations

Treatment of Haemophilia and Other Coagulation Disorders.

1966 • 109 citations

A Plausible Mechanism for Prothrombin Activation by Factor Xa, Factor Va, Phospholipid, and Calcium Ions

1974 • 108 citations

Activation of prothrombin with (taipan snake) venom

1973 • 107 citations

BLOOD COAGULATION INITIATION BY A COMPLEMENT-MEDIATED PATHWAY

1971 • 103 citations

Chemistry of Thrombolysis: Human Fibrinolytic Enzymes.

1963 • 103 citations

Factor XIII Assay by an Isotope Method

1970 • 100 citations

The Function of Ac-Globulin in Blood Clotting

1947 • 99 citations

Coagulation studies on „Reptilase”, an extract of the venom from Bothrops jararaca

1957 • 98 citations

Late results of treatment of deep vein thrombosis

1969 • 97 citations

Biochemistry of Snake Venoms

1970 • 95 citations

Blood-Clotting Enzymology

1968 • 94 citations

The Influence of Fibrin Crosslinking on the Kinetics of Urokinase‐Induced Clot Lysis*

1971 • 94 citations

A Comparative Study of Four Methods for Detecting Fibrinogen Degradation Products in Patients with Various Diseases

1970 • 93 citations

Cooperative calcium binding by the phospholipid binding region of bovine prothrombin: A requirement for intact disulfide bridges

1975 • 93 citations

Vitamin K and the Biosynthesis of Prothrombin

1973 • 93 citations

THE PARADOX IN THERAPEUTIC DEFIBRINATION

1968 • 92 citations

The proteolytic action of Arvin on human fibrinogen

1970 • 91 citations

The Activation of Antihemophilic Factor (Factor VIII) by Activated Christmas Factor (Activated Factor IX)^*

1964 • 90 citations

Activation of human prothrombin by a procoagulant fraction from the venom of Echis carinatus. Identification of a high molecular weight intermediate with thrombin activity.

1975 • 85 citations

In vivo effects of Agkistrodon rhodostoma venom: studies with fibrinogen-131I.

1966 • 84 citations

Interaction of lanthanide ions with bovine factor X and their use in the affinity chromatography of the venom coagulant protein of Vipera russelli

1975 • 84 citations

A Study of the Coagulant Action of Eight Snake Venoms

1964 • 83 citations

A BLOOD COAGULATION ABNORMALITY IN RABBITS DEFICIENT IN THE SIXTH COMPONENT OF COMPLEMENT (C6) AND ITS CORRECTION BY PURIFIED C6

1971 • 82 citations

Pharmacology of Peptides and Proteins in Snake Venoms

1968 • 82 citations

Coagulant Activity of Tiger Snake (Notechis scutatus scutatus) Venom

1966 • 81 citations

THE HÆMOSTATIC POSSIBILITIES OF SNAKE-VENOM

1934 • 81 citations

Actions of Some Coagulant Snake Venoms on Blood Platelets

1965 • 79 citations

Correlations between the enzymatic activities and the factors active on blood coagulation and platelet aggregation from the venom of Vipera aspis

1974 • 77 citations

The proteolytic action of arvin on human fibrinogen

1969 • 76 citations

The Coagulation of blood

1909 • 76 citations

The Hageman Factor Dependent Pathways of Coagulation, Fibrinolysis, and Kinin-Generation

2008 • 75 citations

Relationship of “new” vitamin K-dependent protein C and “old” autoprothrombin II-A

1976 • 74 citations

Enzymic lysis of plasma clots: The influence of fibrin stabilization on lysis rates

1967 • 73 citations

Mechanism of ancrod anticoagulation

1972 • 73 citations

Blood coagulation, hemorrhage and thrombosis

1964 • 72 citations

Purification and characterization of the fibrinolytic principle of Agkistrodon acutus venom

1976 • 71 citations

Inhibitors of Fibrin Cross-linking : Relevance for Thrombolysis

1966 • 70 citations

Characterization of peptides released from human fibrinogen by Arvin

1970 • 69 citations

The proteolytic action of ancrod on human fibrinogen and its polypeptide chains

1973 • 69 citations

A new assay for factor V (proaccelerin-accelerin) using Russell's viper venom.

1960 • 68 citations

Prothrombin

1962 • 67 citations

Fundamental Interactions and Effect of Storage, Ether, Adsorbants and Blood Clotting on Plasma Antithrombin Activity

1952 • 66 citations

Autoprothrombin II-A: Thrombin removal and mechanism of induction of fibrinolysis

1973 • 65 citations

Isolation and some properties of prethrombin and autoprothrombin III

1967 • 62 citations

Retraction of reptilase-clots in the presence of agents inducing or inhibiting the platelet adhesion-aggregation reaction

1973 • 62 citations

PHARMACOLOGY AND TOXICOLOGY OF A DEFIBRINATING SUBSTANCE FROM MALAYAN PIT VIPER VENOM

1968 • 61 citations

The Circulating Platelet

1971 • 61 citations

Decomposition products of fibrinogen and fibrin

1945 • 61 citations

A phospholipase A2 with anticoagulant activity II. Inhibition of the phospholipid activity in coagulation

1976 • 60 citations

Purification and some properties of autoprothrombin II-A: An anticoagulant perhaps also related to fibrinolysis

1972 • 59 citations

Prothrombin and Related Coagulation Factors

1975 • 59 citations

Characterization of the coagulant activity of some snake venoms

1972 • 59 citations

The Effect of Arvin on Blood Coagulation Factors

1968 • 59 citations

Platelets: production, function, transfusion, and storage

1974 • 58 citations

Heparin in the Treatment of Thrombosis

1947 • 58 citations

The Levels of Factors II, VII, IX and X by Antibody Neutralization Techniques in the Plasma of Patients Receiving Phenindione Therapy

1971 • 58 citations

Soluble Fibrin Complexes

2008 • 58 citations

A phospholipase A2 with anticoagulant activity I. Isolation from Vipera berus venom and properties

1976 • 58 citations

The prothrombin-activating principle from Echis carinatus venom

1972 • 57 citations

Mode of Action of Cobra Venom and Its Purified Toxins

1971 • 52 citations

Some biochemical evidence in support of the classification of venomous snakes

1965 • 52 citations

Purification and properties of the anticoagulant principle of agkistrodon acutus venom

1972 • 52 citations

Venins de serpents (lerepartie) physio-pathologie de l'envenimation et proprietes biologiques des venins

1964 • 52 citations

Purification and Properties of the Thrombin-Like Principle of Agkistrodon acutus Venom and Its Comparison with Bovine Thrombin

1971 • 50 citations

Isolation and some properties of thrombin-E and other prothrombin derivatives

1974 • 49 citations

Purification and properties of the thrombin-like enzyme from Trimeresurus gramineus venom

1974 • 48 citations

Clinical aspects of snake venom poisoning in North America

1969 • 46 citations

The acetylation of thrombin.

1959 • 46 citations

Properties of fibrinogen degradation products produced by α- and β-fibrinogenases of Trimeresurus mucrosquamatus snake venom

1979 • 46 citations

Prothrombin Conversion Factor of Dicumarol Plasma.

1948 • 46 citations

Precipitation of Soluble Fibrin Monomer Complexes by Lysosomal Protein Fraction of Polymorphonuclear Leukocytes

1969 • 46 citations

The Purification and Properties of Activated Factor X

1972 • 45 citations

Blood Fibrinolytic Activity during Arvin Therapy

1969 • 45 citations

The proteolytic action of the snake venom enzymes arvin and reptilase on N‐terminal chain‐fragments of human fibrinogen

1971 • 45 citations

Thrombohemorrhagic Phenomena.

1966 • 44 citations

A Study of the Coagulant Properties of Malayan Pit‐Viper Venom

1965 • 44 citations

Inhibition of Platelet Aggregation by Dialysable Fibrinogen Degradation Products (FDP)

1970 • 44 citations

Studies on the Venom of Echis Colorata *

1960 • 43 citations

A Method of Antithrombin Estimation using Plasma Defibrinated with Ancrod

1973 • 43 citations

Two Forms of Human Thrombin

1973 • 42 citations

CONCENTRATION OF PROTHROMBIN AND Ac-GLOBULIN IN VARIOUS SPECIES

1948 • 41 citations

Separation and Partial Characterization of a Coagulant Enzyme from Bitis gabonica Venom

1974 • 39 citations

The Protein and Nonprotein Constituents of Snake Venoms

1968 • 38 citations

Heparin: Structure. Function and Clinical Implications

1976 • 38 citations

36. EVALUATION OF REPTILASE R AND THROMBIN CLOTTING TIME IN THE PRESENCE OF FIBRINOGEN DEGRADATION PRODUCTS AND HEPARIN

1971 • 38 citations

The properties of the purified fibrinolytic principle from Agkistrodon Acutus snake venom

1977 • 38 citations

The effect of proteolytic enzymes on fibrin stabilizing factor

1969 • 38 citations

Changes in platelet behaviour during arvin therapy.

1969 • 37 citations

The factor V activating enzyme of Russell's viper venom

1973 • 37 citations

CORRELATION OF THE MODE OF FIBRIN POLYMERIZATION WITH THE PATTERN OF CROSS‐LINKING*

1972 • 36 citations

Esterase and Clotting Activity Derived From Purified Prothrombin

1957 • 36 citations

Further Experience With the Use of Thrombin as a Hemostatic Agent

1939 • 36 citations

Les venins de seprents agents modificateurs de la coagulation sanguine

1966 • 36 citations

Thrombin-E as a Fibrinolytic Enzyme

1960 • 35 citations

Comparisons of the Molecular Forms of Activated Bovine Factor X

1973 • 35 citations

Effect of Russell's Viper Venom (Stypven) on Stuart Clotting Defect

1956 • 35 citations

Separation of the tosyl arginine esterase activity from the factor X activating enzyme of Russell's Viper venom

1971 • 34 citations

CHANGES IN PLATELET BEHAVIOUR DURING ARVIN THERAPY

1969 • 34 citations

The effect of the purified anticoagulant principle of Agkistrodon acutus venom on blood coagulation

1973 • 33 citations

Defibrinating enzyme from timber rattlesnake () venom: A potential agent for therapeutic defibrination I. Purification and properties

1975 • 33 citations

The intrinsic activation of factor x in blood coagulation

1972 • 33 citations

Blood Clotting Mechanisms: Three Basic Reactions

1969 • 33 citations

Inactivation of ‘Arvin’ by Plasma Proteins

1970 • 32 citations

The prothrombin-activating principle from Echis carinatus venom

1972 • 32 citations

CONTROLLED TRIAL OF ANCROD AND HEPARIN IN TREATMENT OF DEEP-VEIN THROMBOSIS OF LOWER LIMB

1972 • 32 citations

ADP, thrombin, and Bothrops atrox thrombinlike enzyme in platelet-dependent fibrin retraction

1975 • 31 citations

Purification and properties of the anticoagulant principle of Trimeresurus gramineus venom

1975 • 31 citations

Defibrination and metastasis formation

1972 • 31 citations

PURIFICATION AND SOME PROPERTIES OF AUTOPROTHROMBIN C

1963 • 31 citations

Some Physicochemical Properties of Bovine Autoprothrombin II

1962 • 30 citations

Studies of snake venoms on blood coagulation I. The thromboserpentin (thrombin-like) enzyme in the venoms

1973 • 30 citations

Coagulant, Proteolytic, and Hemolytic Properties of Some Snake Venoms

1968 • 30 citations

Isolation of coagulant and anticoagulant principles from the venom of Agkistrodon acutus

1967 • 29 citations

A QUANTITATIVE STUDY OF ANTIFIBRINOLYSIN IN CHICK PLASMA: INCREASE IN ANTIFIBRINOLYSIN ACTIVITY DURING PTEROYLGLUTAMIC ACID DEFICIENCY

1947 • 29 citations

Circulating Fibrinogen Degradation Products (FDP) in Dog Blood after Intravenous Thrombin Infusion

1965 • 29 citations

Dynamics of thrombus formation and dissolution

1970 • 29 citations

Precipitation of ancrod-induced soluble fibrin by aprotinin and norepinephrine

1973 • 28 citations

THE USE OF PURIFIED THROMBIN AS AN HEMOSTATIC AGENT

1939 • 28 citations

Lipids in blood clotting

1965 • 28 citations

Effects of Green Pit Viper (Trimeresurus erythrurusandTrimeresurus popeorum) Venoms on Blood Coagulation, Platelets and the Fibrinolytic Enzyme Systems: Studiesin Vivoandin Vitro

1973 • 28 citations

Tissue extract thromboplastin: Quantitation, fractionation and characterization of protein components

1975 • 27 citations

Prothrombin activation: Ac-Globulin, lipid, platelet membrane, and autoprothrombin C (factor Xa) requirements

1972 • 27 citations

Effects of arvin on blood platelets. In vitro and in vivo studies.

1972 • 27 citations

Management of Priapism by Therapeutic Defibrination

1969 • 27 citations

Precipitation of Soluble Fibrin Monomer Complexes SFMC by Cellular Basic Proteins, and the Antagonistic Effect of Sulfonated Mucopolysaccharides

1970 • 27 citations

The Molecular Structure of Fibrinogen

1974 • 27 citations

Activation of prothrombin with Taipan snake venom

1972 • 27 citations

The action of Arvin on Fibrin Stabilizing Factor (factor 13).

1970 • 26 citations

Effects of Reptilase‐Induced Intravascular Coagulation in Dogs

1970 • 25 citations

Platelet aggregation induced by ADP and thrombin in reptilase defibrinated dogs

1972 • 25 citations

ANCROD IN SICKLE-CELL CRISIS

1972 • 25 citations

The Chemistry of Blood Coagulation

1960 • 24 citations

The Chemistry of Blood Coagulation

1958 • 24 citations

The Coagulation of the Blood. Investigations on a New Clotting Factor. BY PAUL A. OWREN. Oslo, J. Christian Gundersen, 1947

1948 • 24 citations

In Vivo Behaviour of the Coagulant Enzyme from Agkistrodon rhodostoma Venom: Studies Using ¹³¹I‐‘Arvin’*

1969 • 24 citations

The Conversion of Prethrombin to Thrombin

1967 • 24 citations

Fundamentals of Blood Coagulation in Clinical Medicine.

1964 • 24 citations

A Form of Bovine Factor X with a Single Polypeptide Chain

1973 • 23 citations

An Accelerator of Prothrombin Activation Derived From Prothrombin

1955 • 23 citations

Disseminated Intravascular Coagulation

1966 • 23 citations

Human fibrinogen: Some characteristics of its S-carboxymethyl derivative chains

1972 • 22 citations

Two-stage procedure for the quantitative determination of autoprothrombin 3 concentration and some applications.

1967 • 22 citations

Evidence of Antithrombic Activity of the Anticoagulant Fraction of Incubated. Fibrinogen

1966 • 21 citations

Effect of fibrinogen degradation products on platelet aggregation

1968 • 21 citations

Characterization of the venoms of various Bothrops species by immunoelectrophoresis and reaction with fibrinogen agarose

1974 • 21 citations

Anticoagulants and Fibrinolysins

1963 • 21 citations

Production of the Generalized Shwartzman Reaction in Rabbits by Ancrod (‘Arvin’) Infusion and Endotoxin Injection

1973 • 20 citations

Anticoagulation by Ancrod for Haemodialysis

1970 • 20 citations

Mechanical recording of reptilase-clot retraction = effect of adenosine-5′-diphosphate and prostaglandin E1

1974 • 20 citations

Interference of acetyl salicylic acid, heparin and fibrinogen degradation products in haemostasis of reptilase-defibrinogenated dogs

1972 • 19 citations

Inhibitor of Blood Clotting Derived from Prothrombin

1967 • 19 citations

Marine toxins from the Pacific—IX

1971 • 19 citations

Prothrombin in Enzymology, Thrombosis and Hemophilia.

1967 • 18 citations

Profound thrombocytopenia associated with Crotalus ruber ruber envenomation: A clinical case

1971 • 17 citations

Significance of a prothrombin assay method using echis carinatus venom for diagnostic information in disseminated intravascular coagulation syndrome

1975 • 17 citations

ACTION OF SNAKE VENOM ON HUMAN PLATELET PHOSPHOLIPIDS.

1964 • 17 citations

Thromboplastin Generation: Effect of the Bell-Alton Reagent and Russell Viper Venom on Prothrombin Consumption

1971 • 17 citations

Metabolism of iodine-labeled plasminogen during streptokinase and reptilase therapy in man

1973 • 17 citations

Isolation of coagulant and anticoagulant principles from the venom of Trimeresurus gramineus

1965 • 17 citations

On the metabolism of the thrombin-like enzyme from the venom of bothrops atrox

1974 • 16 citations

PHYSIOLOGICAL EFFECTS OF A PLASMA PROTEIN: BLOOD PRESSURE, LEUCOCYTE CONCENTRATION, SMOOTH AND CARDIAC MUSCLE ACTIVITY

1947 • 16 citations

Blood Clotting Activity of Reptilase and Bovine Thrombin in Vitro: A Comparative Study on Seven Different Species

1972 • 16 citations

The effects of the purified thrombin-like and anticoagulant principles of Agkistrodon acutus venom on blood coagulation in vivo

1976 • 16 citations

FIBRINOLYSIS AND THE DEFIBRINATION SYNDROME OF MALAYAN VIPER BITE

1964 • 16 citations

Laboratory manual of hemostasis

1971 • 16 citations

Postprostatectomy Bleeding

1962 • 16 citations

Inhibition of the enzymatic activity of thrombin by concanavalin A

1974 • 15 citations

The Effect of Arvin on Experimental Pulmonary Embolism in the Rabbit

1969 • 15 citations

Action of Snake Venom Phospholipase A on Isolated Platelet Membranes.

1966 • 15 citations

Substitution of Lipids with Bile Salts in the Formation of Thrombin

1969 • 15 citations

Isolation of Thrombin-Like Activity from the Venom of Trimeresurus Okinavensis

1972 • 15 citations

Studies on the Activation of Bovine Prothrombin<xref ref-type="fn" rid="fn1"><sup>*</sup></xref><subtitle>Isolation and Characterization of the Fragments Released from the Prothrombin by Activated Factor X</subtitle>

1974 • 14 citations

Antithrombotic Effect of Malayan Pit Viper Venom on Experimental Thrombosis of the Inferior Vena Cava Produced by a New Method

1966 • 14 citations

A new thrombin: Purification, amino acid composition and crystallization

1972 • 14 citations

Fibrinogen and its derivatives in relationship to ancrod and reptilase

1973 • 14 citations

The effect of Ancistrodon rhodostoma venom in the dog.

1968 • 14 citations

Plasmin Digestion of Stabilized and Non-Stabilized Fibrin Illustrated by pH-Stat Titration and Thrombelastography

1971 • 13 citations

Immunochemical identification of Ancrod (A38414) and Reptilase (Defibrase)

1973 • 13 citations

Blood coagulation as a cybernetic system: Control of autoprothrombin C (factor Xa) formation

1975 • 13 citations

Experimental and clinical studies on the thrombin-like enzyme from the venom of Bothrops atrox. On the primary structure of fragment E.

1973 • 13 citations

Platelets in haemostasis

1968 • 13 citations

Crosslinking of Fibrin

1974 • 13 citations

Mode of Action of Vitamin A

2015 • 13 citations

Studies on a direct latex agglutination technique for the semiquantitation of fibrin/fibrinogen degradation products

1973 • 13 citations

Vein graft surgery in defibrase(R)-Defibrinogenated dogs

1973 • 13 citations

Phospholipid requirements of tissue thromboplastin in blood coagulation

1975 • 13 citations

Rabbit factor V: different effects of thrombin and venom, a source of error in assay

1966 • 13 citations

Clotting of blood with Russell's viper venom.

1955 • 12 citations

A partial gene duplication in the evolution of prothrombin?

1974 • 12 citations

Activation of Purified Prothrombin in Ammonium Sulfate Solutions: Purification of Autoprothrombin C

1966 • 12 citations

Prethrombin and the ultimate formation of thrombin

1973 • 11 citations

Therapeutic Defibrination and Heparin Therapy in the Prevention and Resolution of Experimental Venous Thrombosis

1970 • 11 citations

The effect of thrombin, Reptilase, and a fibrinopeptide B-releasing enzyme from the venom of the Southern Copperhead snake on rabbit platelets

1973 • 10 citations

A study of the relationship between ancrod and thrombin clotting units

1974 • 10 citations

Mechanisms of hemostasis

1968 • 10 citations

A prolonged defibrination caused by venom

1971 • 10 citations

Coagulant and esterase activities of thrombin and Bothrops atrox venom

1972 • 10 citations

Blutgerinnungsfaktoren

1956 • 9 citations

Study of the Clotting, Esterase and Platelet Aggregating Activities of Thrombin, Acetylated Thrombin and Reptilase®

1972 • 9 citations

The Role of Fibrin Monomer and an in vivo Thrombin‐Induced Anticoagulant in Experimental Venous Thrombosis

1974 • 9 citations

Formation of prethrombin-E, thrombin, and thrombin-E and their inhibition with antithrombin and enzyme inhibitors

1974 • 9 citations

The effects of the purified thrombin-like enzyme and anticoagulant principle of Trimeresurus gramineus venom on blood coagulation in vivo

1976 • 9 citations

Transformation of Autoprothrombin III to Autoprothrombin C in Sodium Citrate Solution

1968 • 8 citations

PROTEASES IN THE CLOTTING MECHANISM

1957 • 8 citations

The effect of blockade of the reticuloendothelial system and of hypotension on the response of dogs to Ancistrodon rhodostoma venom.

1968 • 8 citations

Phospholipid requirements in thrombin formation

1974 • 8 citations

Stability Conditions Related to a Previously Unrecognized Form of Thrombin

1972 • 8 citations

Some Effects of Purified Autoprothrombin C in Blood Clotting

1966 • 8 citations

Inhibitory properties of serum proteins on the enzymatic sequence leading to lysis of red blood cells by snake venom

1967 • 8 citations

A simple and sensitive test for the detection of inhibitors of Defibrase® and Arwin® in serum

1975 • 8 citations

FACTOR VIII IN VON WILLEBRAND'S DISEASE

1974 • 8 citations

Anticoagulant Therapy

1961 • 8 citations

A Modified Stypven Test for the Determination of Platelet Factor 3

1971 • 7 citations

The effect of ecarin - defibrinating enzyme isolated from echis carinatus - on experimental arterial thrombosis

1975 • 7 citations

Isolation of L-chain polypeptide of autoprothrombin III (Factor X): Homology with prothrombin indicated

1973 • 7 citations

On fibrin distribution in organs of dogs during defibrination with the thrombin-like enzyme from bothrops atrox

1973 • 7 citations

Action of Lysolecithin on Blood Platelets

1963 • 7 citations

Study of hemolysis in the lethal effect of Naja naja venom in the mouse and guinea pig

1969 • 7 citations

Therapeutic defibrination with Arvin

1970 • 7 citations

Coagulation and Transfusion in Clinical Medicine.

1966 • 7 citations

Inhibition of the thrombin-like principle of Agkistrodon acutus venom by group-specific enzyme inhibitors

1974 • 7 citations

Evidence for multiple molecular forms of autoprothrombin C (Factor Xa)

1973 • 7 citations

Treatment of Snake-bite Poisoning

1963 • 6 citations

Metabolic Formation of a Prothrombin Derivative

1971 • 6 citations

Arvin therapy in experimental pulmonary embolism

1973 • 6 citations

Inhibition of Prothrombin, Thrombin and Autoprothrombin C with Enzyme Inhibitors

1965 • 6 citations

The Diagnosis of Bleeding Disorders.

1970 • 6 citations

[Behavior of I I 125 labeled fibrinogen during therapeutic defibrination with highly purified reptilase ("Defibrase")].

1971 • 6 citations

A change in Russell's viper venom (Stypven): modification of factor V assay to compensate.

1971 • 6 citations

EFFECTS OF VARIOUS HEMOSTYPTIC DRUGS IN RATS

1972 • 6 citations

Reptilase-Induced Shortening of Coagulation Times in Normal and Hemophilic Individuals

1972 • 5 citations

THE ACETYLATION OF THROMBIN

1959 • 5 citations

Some studies on proteins in the defibrinated state during ancrod (A38414) studies in normal humans

1973 • 5 citations

Treatment of experimental venous thrombosis with streptokinase and ancrod (Arvin)

1971 • 5 citations

Platelet Release Reaction and Clot Retraction

1973 • 5 citations

Thrombin and acetylated thrombin in the activation of fibrinolysis

1968 • 5 citations

A Description of Clot Retraction as a Visual Experience

1959 • 5 citations

Blood coagulation: a cybernetic system.

1973 • 4 citations

The effect of Arvin on reticulo‐endothelial activity in rabbits

1970 • 4 citations

On interaction of serum proteins with thrombin-like enzyme from Bothrops atrox venom

1972 • 4 citations

The Effects of Infusing Thrombin and Its Acetylated Derivative

1968 • 4 citations

The Effect of Malayan Pit-Viper (Agkistroden rhodostoma) Venom on Ovine Blood and the Development of Resistance to the Anticoagulant Activity of this Venom

1972 • 3 citations

Studies of actions of snake venoms on blood coagulation II. Electrophoretic analysis of venoms of Viperidae, Crotalidae, Elapidae and Hydrophidae

1973 • 2 citations

Factor VIII in Von Willebrand's Disease

2008 • 2 citations

Coagulation and Transfusion in Clinical Medicine.

1966 • 2 citations

Fibrinolytic properties of thrombin.

1961 • 2 citations

Inhibition of Thrombin

1975 • 2 citations

Versuche zur Klärung des Wirkungsmechanismus der thrombokinaseähnlich wirkenden Komponente des Russell-Vipern-Giftes

1962 • 2 citations

Eosinophil mobilization during disseminated intravascular coagulation.

1969 • 2 citations

Retraction of Reptilase Clots

1975 • 1 citations

Deleted Work

1955 • 0 citations