Prothrombin activation: Ac-Globulin, lipid, platelet membrane, and autoprothrombin C (factor Xa) requirements

An Enzyme Cascade in the Blood Clotting Mechanism, and its Function as a Biochemical Amplifier

1964 • 1,099 citations

Waterfall Sequence for Intrinsic Blood Clotting

1964 • 1,088 citations

Isolation and Characterization of Plasma Membranes from Human Blood Platelets

1970 • 429 citations

FACTORS WHICH INFLUENCE THE ACTIVITY OF PURIFIED THROMBIN

1942 • 197 citations

Activation of Purified Prothrombin to Autoprothrombin I or Autoprothrombin II (Platelet Cofactor II or Autoprothrombin II-A)

1961 • 131 citations

SOME PROPERTIES OF PURIFIED PROTHROMBIN AND ITS ACTIVATION WITH SODIUM CITRATE

1950 • 123 citations

SERUM AC-GLOBULIN: FORMATION FROM PLASMA AC-GLOBULIN; ROLE IN BLOOD COAGULATION; PARTIAL PURIFICATION; PROPERTIES; AND QUANTITATIVE DETERMINATION

1948 • 117 citations

PLASMA ACCELERATOR GLOBULIN: PARTIAL PURIFICATION, QUANTITATIVE DETERMINATION, AND PROPERTIES

1948 • 108 citations

Some Physicochemical Properties of Bovine Thrombin

1961 • 71 citations

Preparation and properties of thrombin

1968 • 70 citations

Isolation and some properties of prethrombin and autoprothrombin III

1967 • 62 citations

Purification and Quantitative Determination of Platelet Factor 3

1955 • 55 citations

CONCENTRATION OF PROTHROMBIN AND Ac-GLOBULIN IN VARIOUS SPECIES

1948 • 41 citations

Some activation characteristics of the prethrombin subunit of prothrombin

1965 • 40 citations

PURIFICATION AND SOME PROPERTIES OF AUTOPROTHROMBIN C

1963 • 38 citations

Thromboplastin: Nomenclature and Preparation of Protein-Free Material Different From Platelet Factor 3 or Lipid Activator

1958 • 38 citations

PURIFICATION OF PROTHROMBIN AND THROMBIN BY CHROMATOGRAPHY ON CELLULOSE

1960 • 37 citations

PURIFICATION AND SOME PROPERTIES OF AUTOPROTHROMBIN C

1963 • 31 citations

Ac-Globulin (Factor V): Preparation of a Practical Product

1972 • 26 citations

The Conversion of Prethrombin to Thrombin

1967 • 24 citations

Two-Stage Procedure for the Quantitative Determination of Autoprothrombin III Concentration and Some Applications

1967 • 23 citations

Two-stage procedure for the quantitative determination of autoprothrombin 3 concentration and some applications.

1967 • 22 citations

Procedures for the Quantitative Determination of Autoprothrombin C

1962 • 22 citations

Further observations on the purification and properties of autoprothrombin III (Factor X)

1972 • 17 citations

The practicality of the use of the steady-state assumption and the inflection point method in enzyme kinetics

1967 • 16 citations

Substitution of Lipids with Bile Salts in the Formation of Thrombin

1969 • 15 citations

Toxicity of Blood Clotting Factors

1962 • 11 citations

Structural Changes in Prothrombin during Activation: A Theory

1970 • 11 citations

Note on the Inactivation of Autoprothrombin C with Diisopropylfluorophosphate or Phenylmethanesulfonyl Fluoride

1969 • 5 citations