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Overexpression of DNA polymerase β: a genomic instability enhancer process

Data up to Jan 2025

Published1999
Citations76
References38

Total Citations Per Year

Abstract

References (38)

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Proliferating cell nuclear antigen is required for DNA excision repair

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Overexpression of DNA polymerase β in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs

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DNA polymerase zeta and the control of DNA damage induced mutagenesis in eukaryotes.

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SPONTANEOUS MUTATION

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DNA polymerase beta bypasses in vitro a single d(GpG)-cisplatin adduct placed on codon 13 of the HRAS gene.

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Human DNA polymerases alpha and beta are able to incorporate anti-HIV deoxynucleotides into DNA.

1992 • 105 citations

Mutator phenotype of BCR – ABL transfected Ba/F3 cell lines and its association with enhanced expression of DNA polymerase β

1999 • 105 citations

Increased Activity and Fidelity of DNA Polymerase β on Single-nucleotide Gapped DNA

1997 • 104 citations

Mammalian DNA polymerase beta can substitute for DNA polymerase I during DNA replication in Escherichia coli.

1992 • 99 citations

Evidence for a role for DNA polymerase β in mammalian meiosis

1997 • 97 citations

Structural insights into DNA polymerase β fidelity: hold tight if you want it right

1998 • 88 citations

Incorporation of the Guanosine Triphosphate Analogs 8-Oxo-dGTP and 8-NH2-dGTP by Reverse Transcriptases and Mammalian DNA Polymerases

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Bypass Replication of the Cisplatin-d(GpG) Lesion by Calf Thymus DNA Polymerase β and Human Immunodeficiency Virus Type I Reverse Transcriptase Is Highly Mutagenic

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1989 • 53 citations

Overexpression of DNA polymerase beta sensitizes mammalian cells to 2',3'-deoxycytidine and 3'-azido-3'-deoxythymidine.

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Reconstitution of Mammalian DNA Replication

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Overexpression of DNA polymerase β: a genomic instability enhancer process (1999) – The FASEB Journal | Metascience Observatory Explorer