Genome-wide hypermutation in a subpopulation of stationary-phase cells underlies recombination-dependent adaptive mutation

Escherichia coli and Salmonella :cellular and molecular biology

1996 • 8,124 citations

MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

1943 • 3,852 citations

Complete Nucleotide Sequence of the Escherichia coli Plasmid pBR322

1979 • 1,807 citations

Positional Cloning of the Werner's Syndrome Gene

1996 • 1,696 citations

The Bloom's syndrome gene product is homologous to RecQ helicases

1995 • 1,371 citations

REPLICA PLATING AND INDIRECT SELECTION OF BACTERIAL MUTANTS

1952 • 1,360 citations

Linkage map of Escherichia coli K-12, edition 7

1983 • 1,250 citations

Biochemistry of homologous recombination in Escherichia coli

1994 • 1,195 citations

The origin of mutants

1988 • 1,029 citations

Bloom Syndrome

1993 • 529 citations

Adaptive reversion of a frameshift mutation in Escherichia coli.

1991 • 495 citations

Mismatch Repair, Genetic Stability, and Cancer

1994 • 429 citations

Collapse and repair of replication forks in Escherichia coli

1995 • 374 citations

Spontaneous point mutations that occur more often when advantageous than when neutral.

1990 • 328 citations

DNA synthesis errors associated with double-strand-break repair.

1995 • 277 citations

Recombination in Adaptive Mutation

1994 • 267 citations

ADAPTIVE MUTATION: The Uses of Adversity

1993 • 255 citations

Adaptive Mutation by Deletions in Small Mononucleotide Repeats

1994 • 228 citations

DIFFERENT RATES OF SPONTANEOUS MUTATION DURING MITOSIS AND MEIOSIS IN YEAST

1962 • 226 citations

GASPing for Life in Stationary Phase

1996 • 202 citations

Adaptive evolution that requires multiple spontaneous mutations. I. Mutations involving an insertion sequence.

1988 • 200 citations

The Directed Mutation Controversy and Neo-Darwinism

1993 • 199 citations

Adaptive Reversion of a Frameshift Mutation in Escherichia coli by Simple Base Deletions in Homopolymeric Runs

1994 • 193 citations

χ AND THE RecBC D ENZYME OF ESCHERICHIA COLI

1994 • 184 citations

Carcinogen-induced mutation spectrum in wild-type, uvrA and umuC strains of Escherichia coli

1984 • 183 citations

Genetic recombination of bacterial plasmid DNA

1983 • 164 citations

Transient mutators: a semiquantitative analysis of the influence of translation and transcription errors on mutation rates.

1991 • 153 citations

Two Enzymes, Both of Which Process Recombination Intermediates, Have Opposite Effects on Adaptive Mutation in Escherichia coli

1996 • 149 citations

Opposing Roles of the Holliday Junction Processing Systems of Escherichia coli in Recombination-Dependent Adaptive Mutation

1996 • 144 citations

Evidence that F Plasmid Transfer Replication Underlies Apparent Adaptive Mutation

1995 • 138 citations

Nonadaptive mutations occur on the F' episome during adaptive mutation conditions in Escherichia coli

1997 • 136 citations

Adaptive reversion of an episomal frameshift mutation in Escherichia coli requires conjugal functions but not actual conjugation.

1995 • 134 citations

SPONTANEOUS MUTATION

1991 • 131 citations

Adaptive Mutation in Escherichia coli : a Role for Conjugation

1995 • 122 citations

SPONTANEOUS MUTATION IN NON-DIVIDING BACTERIA

1955 • 121 citations

Selection-induced mutations occur in yeast.

1992 • 111 citations

D-loops and R-loops: alternative mechanisms for the initiation of chromosome replication in Escherichia coli

1994 • 107 citations

An examination of adaptive reversion in Saccharomyces cerevisiae.

1992 • 107 citations

Proofreading-defective DNA polymerase II increases adaptive mutation in Escherichia coli.

1995 • 106 citations

Population dynamics of a Lac- strain of Escherichia coli during selection for lactose utilization.

1994 • 91 citations

Transcriptional bias: a non-Lamarckian mechanism for substrate-induced mutations.

1989 • 90 citations

Adaptive mutation sequences reproduced by mismatch repair deficiency.

1995 • 80 citations

Mechanism for induction of adaptive mutations in Escherichia coli

1990 • 72 citations

Molecular handles on adaptive mutation

1995 • 56 citations

A direct role for DNA polymerase III in adaptive reversion of a frameshift mutation in Escherichia coli

1997 • 49 citations

SELFER MUTANTS OF SALMONELLA TYPHIMURIUM

1963 • 48 citations

Mutations affecting uridine monophosphate pyrophosphorylase or the argR gene in Escherichia coli

1972 • 46 citations

Diploid yeast cells yield homozygous spontaneous mutations

1993 • 41 citations

In pursuit of a molecular mechanism for adaptive mutation

1994 • 38 citations

„SELFERS”—ATTRIBUTED TO UNEQUAL CROSSOVERS IN SALMONELLA

1962 • 36 citations

Recombination-dependent mutation in non-dividing cells

1996 • 36 citations

Roles of ruvA, ruvC and recG gene functions in normal and DNA damage-inducible replication of the Escherichia coli chromosome.

1994 • 35 citations

Genetics of selection-induced mutations: I. uvrA, uvrB, uvrC, and uvrD are selection-induced specific mutator loci

1995 • 35 citations

Redundant transfer of F' plasmids occurs between Escherichia coli cells during nonlethal selections

1995 • 33 citations

Construction of frameshift mutation hot spots within the tetracycline resistance gene of pBR322

1985 • 30 citations

Cairnsian mutagenesis inEscherichia coli: Genetic evidence for two pathways regulated bymutS andmutL genes

1992 • 25 citations

Orientation of the guanine operon of Escherichia coli K-12 by utilizing strains containing guaB-xse and guaB-upp deletions

1979 • 24 citations

‘Selfers’ and High Mutation Rate during Meiosis in Ascobolus immersus

1964 • 24 citations

Adaptive Mutation: The Uses of Adversity

1993 • 15 citations

Mapping of the gene for cytosine deaminase on theEscherichia coli chromosome

1972 • 12 citations

Response : Directed Mutation

1993 • 8 citations

Deleted Work

1955 • 0 citations