Back to search

High-level expression of IkB-b in the surface epithelium of the colon: in vitro evidence for an immunomodulatory role

Data up to Jan 2025

Published1999
Citations40
References65

Total Citations Per Year

Abstract

References (65)

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Short chain fatty acids in human large intestine, portal, hepatic and venous blood.

1987 • 2,744 citations

Properties of the Novel Proinflammatory Supergene "Intercrine" Cytokine Family

1991 • 1,864 citations

Rel/NF-kappa B/I kappa B family: intimate tales of association and dissociation.

1995 • 1,739 citations

Control of IκB-α Proteolysis by Site-Specific, Signal-Induced Phosphorylation

1995 • 1,443 citations

Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway.

1995 • 1,296 citations

A distinct array of proinflammatory cytokines is expressed in human colon epithelial cells in response to bacterial invasion.

1995 • 1,205 citations

Activation of DNA-binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor

1988 • 1,200 citations

NF-κB Controls Expression of Inhibitor IκBα: Evidence for an Inducible Autoregulatory Pathway

1993 • 1,141 citations

Rapid proteolysis of IκB-α is necessary for activation of transcription factor NF-κB

1993 • 1,129 citations

Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of I kappa B alpha: a mechanism for NF-kappa B activation.

1993 • 1,047 citations

Molecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin 1 and tumor necrosis factor.

1988 • 1,039 citations

[36] Eukaryotic gene transcription with purified components

1983 • 992 citations

IκB-β regulates the persistent response in a biphasic activation of NF-κB

1995 • 780 citations

Treatment of Diversion Colitis with Short-Chain-Fatty Acid Irrigation

1989 • 764 citations

Effect of butyrate enemas on the colonic mucosa in distal ulcerative colitis

1992 • 737 citations

Mapping of the Inducible IκB Phosphorylation Sites That Signal Its Ubiquitination and Degradation†

1996 • 717 citations

Inflammatory Bowel Disease and Adenomas in Mice Expressing a Dominant Negative N-Cadherin

1995 • 672 citations

Mutual regulation of the transcriptional activator NF-kappa B and its inhibitor, I kappa B-alpha.

1993 • 639 citations

NF-kappa B and Sp1 regulate transcription of the human monocyte chemoattractant protein-1 gene.

1994 • 527 citations

Molecular mechanism of interleukin-8 gene expression

1994 • 465 citations

Salmonella typhimurium attachment to human intestinal epithelial monolayers: transcellular signalling to subepithelial neutrophils.

1993 • 460 citations

Inducible Nuclear Expression of Newly Synthesized IκBα Negatively Regulates DNA-Binding and Transcriptional Activities of NF-κB

1995 • 442 citations

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor.

1995 • 431 citations

I kappa B epsilon, a novel member of the Ikappa B family, controls RelA and cRel NF-kappa B activity

1997 • 394 citations

REGULATED mRNA STABILITY

1990 • 279 citations

Rectal irrigation with short-chain fatty acids for distal ulcerative colitis

1991 • 248 citations

Oct-1 and CCAAT/Enhancer-binding Protein (C/EBP) Bind to Overlapping Elements within the Interleukin-8 Promoter

1997 • 231 citations

Preparation of Nuclear and Cytoplasmic Extracts from Mammalian Cells

2006 • 227 citations

Inhibition of proinflammatory molecule production by adenovirus-mediated expression of a nuclear factor kappaB super-repressor in human intestinal epithelial cells.

1998 • 224 citations

Butyrate enema therapy stimulates mucosal repair in experimental colitis in the rat.

1996 • 202 citations

Identification of Newly Transcribed <scp>RNA</scp>

2007 • 192 citations

Inactivation of IκBβ by the Tax Protein of Human T-Cell Leukemia Virus Type 1: a Potential Mechanism for Constitutive Induction of NF-κB

1996 • 166 citations

Intestine-Specific Gene Transcription

1996 • 159 citations

Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor

1995 • 154 citations

Butyrate enemas in experimental colitis and protection against large bowel cancer in a rat model

1996 • 142 citations

Differential cytokine regulation of complement C3, C4, and factor B synthesis in human intestinal epithelial cell line, Caco-2.

1993 • 141 citations

Treatment of refractory ulcerative proctosigmoiditis with butyrate enemas.

1994 • 136 citations

Properties Of The Novel Proinflammatory Supergene Intercrine Cytokine Family

1991 • 136 citations

Participation of the transcription factor C/EBP delta in the acute-phase regulation of the human gene for complement component C3.

1993 • 136 citations

The C-X-C chemokine ENA-78 is preferentially expressed in intestinal epithelium in inflammatory bowel disease

1997 • 129 citations

Differential interactions of Rel-NF-kappa B complexes with I kappa B alpha determine pools of constitutive and inducible NF-kappa B activity.

1994 • 114 citations

INHIBITION OF IL-8 GENE EXPRESSION IN CACO-2 CELLS BY COMPOUNDS WHICH INDUCE HISTONE HYPERACETYLATION

1997 • 113 citations

Intestinal inflammation reduces expression of DRA, a transporter responsible for congenital chloride diarrhea

1998 • 112 citations

Interleukin 8 secretion by colonic crypt cells in vitro: response to injury suppressed by butyrate and enhanced in inflammatory bowel disease.

1995 • 108 citations

Enterocytes are the primary source of the chemokine ENA-78 in normal colon and ulcerative colitis

1997 • 101 citations

Interleukin 1β is expressed predominantly by enterocytes in experimental colitis

1991 • 96 citations

A 58-base-pair region of the human C3 gene confers synergistic inducibility by interleukin-1 and interleukin-6.

1990 • 93 citations

Sucrase-isomaltase gene expression along crypt-villus axis of human small intestine is regulated at level of mRNA abundance

1992 • 89 citations

Isolation and characterization of the human sucrase-isomaltase gene and demonstration of intestine-specific transcriptional elements.

1992 • 78 citations

Butyrate, mesalamine, and factor XIII in experimental colitis in the rat: Effects on transglutaminase activity

1994 • 70 citations

Overexpression of a truncated growth hormone receptor in the sex-linked dwarf chicken: evidence for a splice mutation.

1993 • 56 citations

Guanidinium Methods for Total RNA Preparation

1991 • 55 citations

Alternative Splicing Variants of IκBβ Establish Differential NF-κB Signal Responsiveness in Human Cells

1998 • 46 citations

Overexpression of a truncated growth hormone receptor in the sex-linked dwarf chicken: evidence for a splice mutation

1993 • 36 citations

P450IIB gene expression in rat small intestine: cloning of intestinal P450IIB1 mRNA using the polymerase chain reaction and transcriptional regulation of induction.

1990 • 31 citations

Induction and immunolocalization of manganese superoxide dismutase in acute acetic acid-induced colitis in the rat

1995 • 30 citations

A 58-Base-Pair Region of the Human C3 Gene Confers Synergistic Inducibility by Interleukin-1 and Interleukin-6

1990 • 29 citations

Preparation of Nuclear and Cytoplasmic Extracts from Mammalian Cells

2001 • 21 citations

Regulated mRna Stability

1990 • 18 citations

Intestinal processing of soluble protein antigen

1990 • 7 citations

Intestine-Specific Gene Transcription

1996 • 4 citations

Cited By (0)

Loading...
High-level expression of IkB-b in the surface epithelium of the colon: in vitro evidence… (1999) – Journal of Leukocyte Biology | Metascience Observatory Explorer