Tumor promoters induce changes in the chick embryo fibroblast cytoskeleton

Plasminogen: Purification from Human Plasma by Affinity Chromatography

1970 • 2,160 citations

Proteases and biological control

1976 • 1,380 citations

Protein kinase activity associated with the avian sarcoma virus src gene product.

1978 • 1,137 citations

AN ENZYMATIC FUNCTION ASSOCIATED WITH TRANSFORMATION OF FIBROBLASTS BY ONCOGENIC VIRUSES

1973 • 779 citations

The Function and Mechanism of Promoters of Carcinogenesis

1973 • 759 citations

Fibrinolysis Associated with Oncogenic Transformation

1974 • 444 citations

Patterns of organization of actin and myosin in normal and transformed cultured cells.

1975 • 428 citations

Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src).

1979 • 378 citations

Cocarcinogenic principles from the seed oil of Croton tiglium and from other Euphorbiaceae.

1968 • 376 citations

CONDITIONAL NEOPLASMS AND SUBTHRESHOLD NEOPLASTIC STATES

1941 • 335 citations

Tumour promotor induces plasminogen activator

1976 • 316 citations

Tumor-promoting Agents in Two-stage Carcinogenesis1

2015 • 296 citations

Hexose Transport in Normal and in Rous Sarcoma Virus-transformed Cells

1973 • 281 citations

Changes in cellular glycoproteins after transformation: identification of specific glycoproteins and antigens in sodium dodecyl sulfate gels.

1976 • 269 citations

Tumorigenesis in Mouse Skin: Inhibition by Synthetic Inhibitors of Proteases

1970 • 263 citations

FIBRINOLYSIS ASSOCIATED WITH ONCOGENIC TRANSFORMATION

1973 • 261 citations

Effect of a tumour promoter on myogenesis

1977 • 259 citations

Characterization of a normal avian cell protein related to the avian sarcoma virus transforming gene product

1978 • 251 citations

Phorbol esters stimulate DNA synthesis and ornithine decarboxylase activity in mouse epidermal cell cultures

1976 • 250 citations

Tumor promoters inhibit spontaneous and induced differentiation of murine erythroleukemia cells in culture.

1977 • 238 citations

The effect of phorbol diesters on chicken embryo fibroblasts.

1977 • 236 citations

Inhibition of adipose conversion of 3T3 fibroblasts by tumour promoters

1977 • 218 citations

Temperature-sensitive changes in surface modulating assemblies of fibroblasts transformed by mutants of Rous sarcoma virus.

1976 • 208 citations

Tumor promoters inhibit spontaneous differentiation of Friend erythroleukemia cells in culture.

1977 • 207 citations

Tumor promoter induces sister chromatid exchanges: relevance to mechanisms of carcinogenesis.

1978 • 206 citations

Transformation of chondroblasts by rous sarcoma virus and synthesis of the sulfated proteoglycan matrix

1977 • 190 citations

Effect of oncogenic virus on muscle differentiation.

1975 • 182 citations

Temperature-sensitive expression of differentiation in transformed myoblasts

1975 • 172 citations

Phorbol ester-induced morphological changes in transformed chick fibroblasts: Evidence for direct catalytic involvement of plasminogen activator

1979 • 168 citations

Sequential Aspects of Chemical Carcinogenesis: Skin

1975 • 159 citations

Effect of a phorbol ester on a transformation-sensitive surface protein of chick fibroblasts

1976 • 159 citations

Actin-containing cables within anchorage-dependent rat embryo cells are dissociated by plasmin and trypsin

1975 • 154 citations

Plasminogen Activator Production Accompanies Loss of Anchorage Regulation in Transformation of Primary Rat Embryo Cells by Simian Virus 40

1974 • 151 citations

Inhibition of tumorigenesis in mouse skin by leupeptin, a protease inhibitor from Actinomycetes.

1972 • 142 citations

Stimulation of prostaglandin synthesis by tumor-promoting phorbol-12, 13-diesters in canine kidney (MDCK) cells. Cycloheximide inhibits the stimulated prostaglandin synthesis, deacylation of lipids, and morphological changes

1978 • 142 citations

Plasminogen, the Serum Proenzyme Activated by Factors from Cells Transformed by Oncogenic Viruses

1974 • 139 citations

Hormonally induced cell shape changes in cultured rat ovarian granulosa cells.

1979 • 137 citations

THE CARCINOGENIC EFFECT OF A PAPILLOMA VIRUS ON THE TARRED SKIN OF RABBITS

1938 • 122 citations

Transformation of chicken embryo retinal melanoblasts by a temperature-sensitive mutant of rous sarcoma virus

1977 • 116 citations

Effect of tumor promoters, protease inhibitors, and repair processes on x-ray-induced sister chromatid exchanges in mouse cells.

1979 • 104 citations

Alterations in surface proteins in chicken cells transformed by temperature-sensitive mutants of Rous sarcoma virus

1975 • 103 citations

Growth stimulation of human diploid fibro‐blasts by the tumor promoter, 12‐0‐tetradecanoyl‐phorbol‐13‐acetate

1974 • 101 citations

Loss of Ability to Synthesize Collagen in Fibroblasts Transformed by Rous Sarcoma Virus 2

1975 • 97 citations

Effects of phorbol-12-myristate-13-acetate on the phenotypic program of cultured chondroblasts and fibroblasts.

1978 • 94 citations

Tubulin and actin in paired nonneoplastic and spontaneously transformed neoplastic cell lines in vitro: Fluorescent antibody studies

1978 • 91 citations

Induction of cell division: Role of cell membrane sites

1972 • 90 citations

Synergistic effect of tumor virus transformation and tumor promoter treatment on the production of plasminogen activator by chick embryo fibroblasts.

1978 • 85 citations

Phorbol esters as a tool in cell research?

1972 • 83 citations

Stimulation of choline incorporation in cell cultures by phorbol derivatives and its correlation with their irritant and tumor-promoting activity.

1979 • 78 citations

Hot lines in the Earth's mantle

1976 • 72 citations

Activation of cell membrane enzymes in the stimulation of cell division

1972 • 71 citations

Muscle Differentiation in Cell Culture

1972 • 68 citations

Production of plasminogen activator by established cell lines of mouse origin.

1977 • 63 citations

Failure of cultured chick embryo fibroblasts to incorporate collagen into their extracellular matrix when transformed by Rous sarcoma virus. An effect of transformation but not of virus production.

1977 • 62 citations

Induction of plasminogen activator in cultured cells by macrocyclic plant diterpene esters and other agents related to tumor promotion.

1978 • 61 citations

Inflammatory, tumor initiating and promoting activities of polycyclic aromatic hydrocarbons and diterpene esters in mouse skin as compared with their prostaglandin releasing potency in vitro

1978 • 61 citations

Phorbol-12-myristate-13-acetate effect on cyclic adenosine 3',5'-monophosphate levels in mouse skin and inhibition of phorbol-myristate-acetate-promoted tumorigenesis by theophylline.

1974 • 51 citations

Transformation of chicken chondrocytes by Rous sarcoma virus.

1977 • 46 citations

Primary avian tendon cells in culture. An improved system for understanding malignant transformation.

1978 • 45 citations

Cellular transformation and differentiation. Effect of Rous sarcoma virus transformation on sulfated proteoglycan synthesis by chicken chondrocytes.

1977 • 40 citations

Assay for early cytoplasmic effects of the src gene product of Rous sarcoma virus

1978 • 37 citations

Selective lysis of cells transformed by Rous sarcoma virus

1971 • 32 citations

Plasmin-mediated agglutination by concanavalin A of 3T3 cells cocultured with SV40–3T3 transformants

1976 • 8 citations