Chronic administration of a glycine partial agonist alters the expression of N-methyl-D-aspartate receptor subunit mRNAs.

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

1992 • 2,527 citations

Excitotoxic cell death

1992 • 2,307 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

Requirement for Glycine in Activation of NMDA-Receptors Expressed in Xenopus Oocytes

1988 • 1,415 citations

Molecular diversity of the NMDA receptor channel

1992 • 1,354 citations

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

1994 • 1,342 citations

A Complete Protocol forIn SituHybridization of Messenger RNAs in Brain and Other Tissues With Radio-labeled Single-Stranded RNA Probes

1989 • 883 citations

Structure and function of the NMDA receptor channel

1995 • 645 citations

Ligand affinities at recombinant receptors depend on subunit composition

1994 • 381 citations

Excitatory amino acids and neuropsychiatrie disorders

1989 • 327 citations

Glutamate and Parkinson’s disease

1996 • 315 citations

Comparative Effect of Transient Global Ischemia on Extracellular Levels of Glutamate, Glycine, and γ‐Aminobutyric Acid in Vulnerable and Nonvulnerable Brain Regions in the Rat

1991 • 299 citations

Bioenergetics and glutamate excitotoxicity

1996 • 245 citations

Glutamate and related acidic excitatory neurotransmitters: from basic science to clinical application

1987 • 195 citations

The excitatory amino acid antagonist d-CPP-ene (SDZ EAA-494) in patients with epilepsy

1993 • 194 citations

Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid.

1993 • 192 citations

AMPA, but not NMDA, receptor antagonism is neuroprotective in gerbil global ischaemia, even when delayed 24 h

1993 • 192 citations

Preferential co-assembly of recombinant NMDA receptors composed of three different subunits

1993 • 190 citations

N-methyl-D-aspartate receptors: different subunit requirements for binding of glutamate antagonists, glycine antagonists, and channel-blocking agents.

1994 • 166 citations

Indole-2-Carboxylic Acid: A Competitive Antagonist of Potentiation by Glycine at the NMDA Receptor

1989 • 138 citations

1‐Aminocyclopropane Carboxylic Acid: A Potent and Selective Ligand for the Glycine Modulatory Site of the N‐Methyl‐<scp>d</scp>‐Aspartate Receptor Complex

1989 • 120 citations

Attenuation of Excitatory Amino Acid Toxicity by Metabotropic Glutamate Receptor Agonists and Aniracetam in Primary Cultures of Cerebellar Granule Cells

1993 • 109 citations

The role of excitatory amino acids in experimental models of Parkinson's disease

1994 • 95 citations

Pharmacological characteristics of cyclic homologues of glycine at the N-methyl-d-aspartate receptor-associated glycine site

1990 • 76 citations

Blockade of N-methyl-D-aspartate induced convulsions by 1-aminocyclopropanecarboxylates

1989 • 75 citations

Desensitization of the NMDA receptor complex by glycinergic ligands in cerebellar granule cell cultures

1993 • 69 citations

[3H]5,7-Dichlorokynurenic acid, a novel radioligand labels NMDA receptor-associated glycine binding sites

1991 • 66 citations

A novel treatment of global cerebral ischaemia with a glycine partial agonist

1992 • 65 citations

Pharmacological effects of the non-competitive NMDA antagonist CNS 1102 in normal volunteers.

1994 • 54 citations

1 ‐Aminocyclopropanecarboxylic Acid: Mouse to Man lnterspecies Pharmacokinetic Comparisons and Allometric Relationships

1995 • 34 citations

1-Aminocyclopropanecarboxylic acid protects against dynorphin A-induced spinal injury

1994 • 32 citations

Neuroprotective actions of 1-aminocyclopropanecarboxylic acid (ACPC): A partial agonist at strychnine-insensitive glycine sites

1995 • 27 citations

Sustained exposure to 1-aminocyclopropanecarboxylic acid, a glycine partial agonist, alters N-methyl-D-aspartate receptor function and subunit composition.

1995 • 21 citations

Discriminative stimulus effects of R-(+)-3-amino-1-hydroxypyrrolid-2-one, [(+)-HA-966], a partial agonist of the strychnine-insensitive modulatory site of the N-methyl-D-aspartate receptor.

1995 • 20 citations

1-Aminocyclopropane-carboxylic acid reduces NMDA-induced neurodegeneration in vivo

1996 • 15 citations

Effect of 1‐aminocyclopropanecarboxylic acid on N‐methyl‐<scp>d</scp>‐aspartate‐stimulated [³H]‐noradrenaline release in rat hippocampal synaptosomes

1996 • 10 citations