Ligand affinities at recombinant receptors depend on subunit composition

A synaptic model of memory: long-term potentiation in the hippocampus

1993 • 11,303 citations

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

High-efficiency transformation of mammalian cells by plasmid DNA.

1987 • 5,377 citations

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1994 • 3,437 citations

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

Heteromeric NMDA Receptors: Molecular and Functional Distinction of Subtypes

1992 • 2,527 citations

Molecular cloning and characterization of the rat NMDA receptor

1991 • 1,780 citations

Molecular diversity of the NMDA receptor channel

1992 • 1,354 citations

Molecular characterization of the family of the N-methyl-D-aspartate receptor subunits.

1993 • 978 citations

Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: selectivity and mechanisms at recombinant heteromeric receptors.

1993 • 828 citations

Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs

1992 • 805 citations

Cooperative Modulation of [³H]MK‐801 Binding to the N‐Methyl‐d‐Aspartate Receptor‐Ion Channel Complex by l‐Glutamate, Glycine, and Polyamines

1988 • 755 citations

A Glycine Site Associated with N‐Methyl‐<scp>d</scp>‐Aspartic Acid Receptors: Characterization and Identification of a New Class of Antagonists

1989 • 723 citations

Developmental changes in distribution of NMDA receptor channel subunit mRNAs

1992 • 718 citations

Zinc potentiates agonist-lnduced currents at certain splice variants of the NMDA receptor

1993 • 605 citations

Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing

1992 • 521 citations

Two classes of N-methyl-D-aspartate recognition sites: differential distribution and differential regulation by glycine.

1988 • 495 citations

[³H]MK‐801 Labels a Site on the N‐Methyl‐D‐Aspartate Receptor Channel Complex in Rat Brain Membranes

1988 • 453 citations

Developmental switch in the expression of NMDA receptors occurs in vivo and in vitro

1993 • 447 citations

Regional and developmental heterogeneity in splicing of the rat brain NMDAR1 mRNA

1994 • 405 citations

Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-d-aspartate receptor

1991 • 333 citations

Mammalian ionotropic glutamate receptors

1993 • 312 citations

Cloning and expression of the ε4 subunit of the NMDA receptor channel

1992 • 296 citations

Cloning, expression and modulation of a mouse NMDA receptor subunit

1992 • 291 citations

Anatomic correlation of NMDA and 3H-TCP-labeled receptors in rat brain

1988 • 284 citations

Single-channel conductances of NMDA receptors expressed from cloned cDNAs: comparison with native receptors

1992 • 261 citations

Glycine and D-serine increase the affinity of N-methyl-D-aspartate sensitive glutamate binding sites in rat brain synaptic membranes

1988 • 258 citations

[3H]CGP 39653: a new N-methyl-D-aspartate antagonist radioligand with low nanomolar affinity in rat brain

1991 • 212 citations

Taking apart NMDA receptors

1987 • 209 citations

Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine

1991 • 198 citations

Preferential co-assembly of recombinant NMDA receptors composed of three different subunits

1993 • 190 citations

Quantitative autoradiography of [³H]‐MK‐801 binding sites in mammalian brain

1988 • 173 citations

Protein chemical characterization and immunocytochemical localization of the NMDA receptor subunit NMDA R1.

1993 • 155 citations

Regulation of hippocampal NMDA receptors by magnesium and glycine during development.

1991 • 124 citations

Regionally Distinct N‐Methyl‐<scp>D</scp>‐Aspartate Receptors Distinguished by Quantitative Autoradiography of [³H]MK‐801 Binding in Rat Brain

1993 • 81 citations

Quinolinate differentiates between forebrain and cerebellar NMDA receptors

1991 • 81 citations

Differential stimulation of [3H]MK-801 binding to subpopulations of NMDA receptors

1991 • 79 citations

Regional Variations in [³H]MK801 Binding to Rat Brain N‐Methyl‐D‐Aspartate Receptors

1991 • 77 citations

Glycine and d-serine act as positive modulators of signal transduction at N-methyl-d-aspartate sensitive glutamate receptors in cultured cerebellar granule cells

1989 • 72 citations

Immunological Detection of the NMDAR1 Glutamate Receptor Subunit Expressed in Human Embryonic Kidney 293 Cells and in Rat Brain

1992 • 71 citations

Characterization and regional distribution of strychnine-insensitive [3H]glycine binding sites in rat brain by quantitative receptor autoradiography

1990 • 71 citations

Identification of a novel NMDA receptor in rat cerebellum

1991 • 70 citations

Identification of a Novel N‐Methyl‐D‐Aspartate Receptor Population in the Rat Medial Thalamus

1992 • 67 citations

Postnatal development of the excitatory amino acid system in visual cortex of the rat. Changes in ligand binding to NMDA, quisqualate and kainate receptors

1990 • 66 citations

Heterogeneity of the N-methyl-D-aspartate receptor ionophore complex in rat brain, as revealed by ligand binding techniques.

1991 • 66 citations

[3H]5,7-Dichlorokynurenic acid, a novel radioligand labels NMDA receptor-associated glycine binding sites

1991 • 66 citations

Developmental changes in the sensitivity of the N-methyl-D-aspartate receptor to polyamines.

1991 • 56 citations

Transient expression of the NR2C subunit of the NMDA receptor in developing rat brain

1993 • 54 citations

Molecular target size analyses of the NMDA-receptor complex in rat cortex

1989 • 51 citations

Quantitative autoradiographic characterization of the binding of (+)-5-methyl-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5, 10-imine ([3H]MK-801) in rat brain: regional effects of polyamines.

1991 • 45 citations

Glycine-insensitive NMDA-sensitive receptor expressed in Xenopus oocytes by guinea pig cerebellar mRNA

1990 • 44 citations

A novel photoaffinity ligand for the phencyclidine site of the N-methyl-D-aspartate receptor labels a Mr 120,000 polypeptide.

1990 • 27 citations

Modulatory effects of aluminum, calcium, lithium, magnesium, and zinc ions on [ 3H]MK-801 binding in human cerebral cortex

1989 • 27 citations

The (NMDA) receptor complex: A stoichiometric analysis of radioligand binding domains

1989 • 26 citations

Receptor sub-types involved in responses of purkinje cell to exogenous excitatory amino acids and local electrical stimulation in cerebellar slices in the rat

1991 • 23 citations

The N-methyl-D-aspartate receptor channel complex and the σ site have different target sizes

1989 • 12 citations

Pharmacologically-distinct NMDA receptor populations of the cerebellum, medial thalamic nuclei and forebrain

1992 • 12 citations

[³H] 5,7-Dichlorokynurenic Acid, a High Affinity Ligand for the NMDA Receptor Glycine Regulatory Site

1991 • 8 citations