Blockade of N-methyl-D-aspartate induced convulsions by 1-aminocyclopropanecarboxylates

Glutamate neurotoxicity and diseases of the nervous system

1988 • 7,257 citations

Glycine potentiates the NMDA response in cultured mouse brain neurons

1987 • 3,116 citations

Requirement for Glycine in Activation of NMDA-Receptors Expressed in Xenopus Oocytes

1988 • 1,415 citations

Selective antagonists of benzodiazepines

1981 • 1,235 citations

Cooperative Modulation of [³H]MK‐801 Binding to the N‐Methyl‐d‐Aspartate Receptor‐Ion Channel Complex by l‐Glutamate, Glycine, and Polyamines

1988 • 755 citations

Anticonvulsant Action of Excitatory Amino Acid Antagonists

1982 • 692 citations

Anticonvulsant activity of (+)‐5‐methyl‐10, 11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 496 citations

Glycine receptor: light microscopic autoradiographic localization with [3H]strychnine

1981 • 296 citations

Protection against chemically induced seizures by 2-amino-7-phosphonoheptanoic acid

1982 • 258 citations

Light microscopic autoradiographic localisation of [3H]glycine and [3H]strychnine binding sites in rat brain

1986 • 247 citations

Taking apart NMDA receptors

1987 • 209 citations

Glutamate and related acidic excitatory neurotransmitters: from basic science to clinical application

1987 • 195 citations

Is Glycine a Neurotransmitter ?: Inhibition of Motoneurones by Iontophoresis of Glycine

1967 • 189 citations

Muscle relaxant and anticonvulsant activity of 3-((±)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid, a novel antagonist, in rodents

1987 • 189 citations

Determination of the Equilibrium Dissociation Constants and Number of Glycine Binding Sites in Several Areas of the Rat Central Nervous System, Using a Sodium‐Independent System

1981 • 169 citations

Glycine modulates [3H]MK-801 binding to the NMDA receptor in rat brain

1987 • 160 citations

Indole-2-Carboxylic Acid: A Competitive Antagonist of Potentiation by Glycine at the NMDA Receptor

1989 • 138 citations

Restoration of shock‐suppressed behavior by treatment with (+)‐5‐methyl‐10,11‐dihydro‐5H‐dibenzo[a, d]cyclohepten‐5, 10‐imine (MK‐801), a substance with potent anticonvulsant, central sympathomimetic, and apparent anxiolytic properties

1982 • 137 citations

Biochemical Aspects of Transmission at Inhibitory Synapses: The Role of Glycine

1978 • 136 citations

Structural requirements for activation of the glycine receptor that modulates the N-methyl-D-aspartate operated ion channel

1988 • 120 citations

1‐Aminocyclopropane Carboxylic Acid: A Potent and Selective Ligand for the Glycine Modulatory Site of the N‐Methyl‐<scp>d</scp>‐Aspartate Receptor Complex

1989 • 120 citations

Antagonism of N-methyl-D,L-aspartic acid-induced convulsions by antiepileptic drugs and other agents

1985 • 117 citations

2-amino-7-phosphonoheptanoic acid (AP7) produces discriminative stimuli and anticonflict effects similar to diazepam

1986 • 108 citations

Anticonvulsant effects of phencyclidine-like drugs: relation to N-methyl-d-aspartic acid antagonism

1988 • 99 citations

Evaluation of CPP, a selective NMDA antagonist, in various rodent models of epilepsy. Comparison with other NMDA antagonists, and with diazepam and phenobarbital

1988 • 84 citations

The glycine receptor: pharmacological studies and mathematical modeling of the allosteric interaction between the glycine- and strychnine-binding sites.

1986 • 80 citations

Peptide sweeteners. 6. Structural studies on the C-terminal amino acid of L-aspartyl dipeptide sweeteners

1984 • 60 citations

[3H]glycine binding is modulated by Mg2+ and other ligands of the NMDA receptor-cation channel complex

1988 • 53 citations

1-Aminocyclopropane-1-carboxylic acid (ACC) mimics the effects of glycine on the NMDA receptor ion channel

1988 • 50 citations

The N-methyl-D-aspartate antagonist, 2-amino-7-phosphonoheptanoate, produces phencyclidine-like behavioral effects in rats

1987 • 40 citations

.alpha.-Effect nucleophiles: a novel and convenient method for the synthesis of dibenzo[a,d]cycloheptenimines

1988 • 37 citations

Differential electrophysiological and behavioral responses to optically active derivatives of phencyclidine

1981 • 35 citations

Inactivation of .gamma.-aminobutyric acid aminotransferase by (S,E)-4-amino-5-fluoropent-2-enoic acid and effect on the enzyme of (E)-3-(1-aminocyclopropyl)-2-propenoic acid

1986 • 24 citations

Stereoselective inhibition of 3H-glycine binding to cortical membranes of rat brain by amino acids

1988 • 15 citations

Red Flints in the Chalk

1882 • 2 citations