Expression of protein kinase C isozymes in guinea pig epidermis: selective inhibition of PKC-beta activity by 13-hydroxyoctadecadienoic acid-containing diacylglycerol.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

The role of protein kinase C in cell surface signal transduction and tumour promotion

1984 • 7,521 citations

Inositol trisphosphate, a novel second messenger in cellular signal transduction

1984 • 6,088 citations

Studies and Perspectives of Protein Kinase C

1986 • 5,148 citations

Inositol trisphosphate and diacylglycerol as second messengers

1984 • 3,535 citations

Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.

1986 • 1,150 citations

Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts

1983 • 721 citations

The Role of Protein Kinase C in Transmembrane Signalling

1986 • 557 citations

Inositol trisphosphate formation and calcium mobilization in Swiss 3T3 cells in response to platelet-derived growth factor

1984 • 520 citations

Tissue-specific expression of three distinct types of rabbit protein kinase C

1987 • 469 citations

The mechanism of protein kinase C activation

1989 • 423 citations

Inhibition of phorbol ester-dependent differentiation of human promyelocytic leukemic (HL-60) cells by sphinganine and other long-chain bases.

1986 • 307 citations

Inhibition of the oxidative burst in human neutrophils by sphingoid long-chain bases. Role of protein kinase C in activation of the burst.

1986 • 294 citations

Potent and Specific Inhibitors of Protein Kinase C of Microbial Origin

1990 • 262 citations

Specificity and mechanism of protein kinase C activation by sn-1,2-diacylglycerols.

1986 • 254 citations

Specificity of the Fatty Acyl Moieties of Diacylglycerol for the Activation of Calcium-Activated, Phospholipid-Dependent Protein Kinase1

1982 • 182 citations

The identification of hydroxy fatty acids in psoriatic skin

1983 • 171 citations

Purification and characterisation of bovine brain protein kinase C isotypes α, β and γ

1989 • 169 citations

Platelet-derived growth factor stimulates Na+/H+ exchange and induces cytoplasmic alkalinization in NR6 cells.

1983 • 145 citations

Expression of the alpha, beta II, and gamma protein kinase C isozymes in the baculovirus-insect cell expression system. Purification and characterization of the individual isoforms.

1990 • 120 citations

Sphingosine Inhibits Phorbol Ester-Induced Inflammation, Ornithine Decarboxylase Activity, and Activation of Protein Kinase C in Mouse Skin

1988 • 99 citations

Altered subcellular distribution of protein kinase C (a phorbol ester receptor). Possible role in tumor promotion and the regulation of cell growth: relationship to changes in adenylate cyclase activity.

1985 • 88 citations

Oxidative metabolism of dihomogammalinolenic acid by guinea pig epidermis: Evidence of generation of anti-inflammatory products

1988 • 86 citations

Characterization of cytosolic calcium-activated phospholipid-dependent protein kinase activity in embryonal carcinoma cells. Effect of retinoc acid-induced differentiation of F9 cells to parietal endoderm.

1983 • 86 citations

Monoclonal antibodies specific for type 3 protein kinase C recognize distinct domains of protein kinase C and inhibit in vitro functional activity.

1988 • 83 citations

Induction of Epidermal Hyperproliferation by Topical n-3 Polyunsaturated Fatty Acids on Guinea Pig Skin Linked to Decreased Levels of 13-Hydroxyoctadecadienoic Acid (13-Hode)

1990 • 82 citations

Increased Phospholipase C-Catalyzed Hydrolysis of Phosphatidylinositol-4,5-Bisphosphate and 1,2-sn-Diacylglycerol Content in Psoriatic Involved Compared to Uninvolved and Normal Epidermis

1990 • 54 citations

Structural studies on the diglyceride-mediated activation of protein kinase C.

1988 • 46 citations

Ionic responses rapidly elicited by porcine platelet-derived growth factor in Swiss 3T3 cells.

1984 • 46 citations

Incorporation of 13-hydroxyoctadecadienoic acid (13-HODE) into epidermal ceramides and phospholipids: phospholipase C-catalyzed release of novel 13-HODE-containing diacylglycerol.

1994 • 42 citations

Immunohistological identification of protein kinase C isozymes in normal and psoriatic epidermis

1988 • 18 citations

Phorbol ester inhibits 13‐cis‐retinoic acid‐induced hydrolysis of phosphatidylinositol 4,5‐bisphosphate in cultured murine keratinocytes: A possible negative feedback via protein kinase C‐activation

1991 • 6 citations