Synergistic effects of 8-chlorocyclic-AMP and retinoic acid on induction of apoptosis in Ewing's sarcoma CHP-100 cells.

Cleavage of poly(ADP-ribose) polymerase by a proteinase with properties like ICE

1994 • 2,575 citations

Phosphorylation-Dephosphorylation of Enzymes

1979 • 2,205 citations

Apoptosis in cancer therapy: Crossing the threshold

1994 • 1,351 citations

Protease activation during apoptosis: Death by a thousand cuts?

1995 • 1,335 citations

Induction of apoptosis in cultured hepatocytes and in regressing liver by transforming growth factor beta 1.

1992 • 675 citations

The retinoid receptors.

1994 • 665 citations

Cyclic nucleotide-dependent protein kinases

1991 • 487 citations

Role of cyclic AMP receptor proteins in growth, differentiation, and suppression of malignancy: new approaches to therapy.

1990 • 281 citations

Differential effects of N-(4-hydroxyphenyl)retinamide and retinoic acid on neuroblastoma cells: apoptosis versus differentiation.

1995 • 195 citations

Mechanisms of transactivation by retinoic acid receptors

1993 • 156 citations

Analysis of the cAMP-Dependent Protein Kinase System Using Molecular Genetic Approaches

1988 • 148 citations

A single-injection protein kinase A-directed antisense treatment to inhibit tumour growth

1995 • 138 citations

Multiple kinase arrest points in the G1 phase of nontransformed mammalian cells are absent in transformed cells.

1992 • 131 citations

Biosynthesis and Metabolism of Retinoic Aid: Roles of CRBP and CRABP in Retinoic Acid: Roles of CRBP and CRABP in Retinoic Acid Homeostasis

1993 • 128 citations

Molecular Cloning, Complementary Deoxyribonucleic Acid Structure and Predicted Full-Length Amino Acid Sequence of the Hormone-lnducible Regulatory Subunit of 3′-5′-Cyclic Adenosine Monophosphate-Dependent Protein Kinase from Human Testis

1988 • 124 citations

Differentiation of HL-60 leukemia by type I regulatory subunit antisense oligodeoxynucleotide of cAMP-dependent protein kinase.

1991 • 108 citations

Retinoid chemoprevention of aerodigestive cancer: From basic research to the clinic

1995 • 95 citations

Identification and differential expression of two forms of regulatory subunits (RII) of cAMP-dependent protein kinase II in Friend erythroleukemic cells. Differentiation and 8-bromo-cAMP elicit a large and selective increase in the rate of biosynthesis of only one type of RII.

1985 • 94 citations

An antisense oligodeoxynucleotide that depletes RI alpha subunit of cyclic AMP-dependent protein kinase induces growth inhibition in human cancer cells.

1993 • 88 citations

Myeloid differentiation and retinoblastoma phosphorylation changes in HL-60 cells induced by retinoic acid receptor- and retinoid X receptor- selective retinoic acid analogs

1996 • 69 citations

A cyclic AMP response element is involved in retinoic acid-dependent RARβ2 promoter activation

1992 • 53 citations

Antisense depletion of RIα subunit of protein kinase A induces apoptosis and growth arrest in human breast cancer cells

1998 • 28 citations