Analysis of the cAMP-Dependent Protein Kinase System Using Molecular Genetic Approaches

Phosphorylation-Dephosphorylation of Enzymes

1979 • 2,205 citations

PROTEIN SERINE/THREONINE KINASES

1987 • 1,457 citations

Identification of a cyclic-AMP-responsive element within the rat somatostatin gene.

1986 • 1,424 citations

An Adenosine 3′,5′-Monophosphate-dependant Protein Kinase from Rabbit Skeletal Muscle

1968 • 1,423 citations

Binding of a nuclear protein to the cyclic-AMP response element of the somatostatin gene

1987 • 1,364 citations

A cyclic nucleotide-gated conductance in olfactory receptor cilia

1987 • 1,134 citations

Purification and Properties of Rabbit Skeletal Muscle Adenosine 3',5'-Monophosphate-dependent Protein Kinases

1971 • 810 citations

Cloning and expression of multiple protein kinase C cDNAs

1986 • 683 citations

Multihormonal regulation of phosphoenolpyruvate carboxykinase gene transcription. The dominant role of insulin.

1984 • 436 citations

Protein Kinases* *Support of the National Institutes of Arthritis and Metabolic Diseases, NIH, U. S. Public Health Service (AM 12842), the Muscular Dystrophy Association of America, and the American Heart Association is acknowledged.

1972 • 416 citations

The covalent modification of eukaryotic proteins with lipid.

1987 • 319 citations

Cyclic AMP regulation of the human glycoprotein hormone alpha-subunit gene is mediated by an 18-base-pair element.

1987 • 293 citations

Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase.

1986 • 286 citations

Isolation of cDNA clones coding for the catalytic subunit of mouse cAMP-dependent protein kinase.

1986 • 275 citations

Molecular cloning, cDNA structure, and regulation of the regulatory subunit of type II cAMP-dependent protein kinase from rat ovarian granulosa cells.

1986 • 254 citations

Amino acid sequence of the regulatory subunit of bovine type I cAMP-dependent protein kinase

1984 • 253 citations

Inhibition of intracellular cAMP-dependent protein kinase using mutant genes of the regulatory type I subunit.

1987 • 248 citations

The molecular cloning of a type II regulatory subunit of the cAMP-dependent protein kinase from rat skeletal muscle and mouse brain.

1987 • 223 citations

Rous sarcoma virus transforming protein lacking myristic acid phosphorylates known polypeptide substrates without inducing transformation

1986 • 223 citations

A cloned bovine cDNA encodes an alternate form of the catalytic subunit of cAMP-dependent protein kinase.

1986 • 206 citations

THE PROPERTIES OF AN ADENINE RIBONUCLEOTIDE PRODUCED WITH CELLULAR PARTICLES, ATP, Mg⁺⁺, AND EPINEPHRINE OR GLUCAGON

1957 • 204 citations

Expression of cDNAs for two isoforms of the catalytic subunit of cAMP-dependent protein kinase.

1987 • 194 citations

Amino acid sequence of the catalytic subunit of bovine type II adenosine cyclic 3',5'-phosphate-dependent protein kinase

1983 • 185 citations

Isolation of a cDNA clone for the type I regulatory subunit of bovine cAMP-dependent protein kinase.

1983 • 177 citations

Insulin action is blocked by a monoclonal antibody that inhibits the insulin receptor kinase.

1986 • 142 citations

Amino acid sequence of the regulatory subunit of bovine type II cAMP-dependent protein kinase

1984 • 128 citations

Turnover of regulatory subunit of cyclic AMP-dependent protein kinase in S49 mouse lymphoma cells. Regulation by catalytic subunit and analogs of cyclic AMP.

1981 • 108 citations

Coincident start sites for divergent transcripts at a randomly selected CpG-rich island of mouse.

1987 • 98 citations

Axokinin phosphorylation by cAMP-dependent protein kinase is sufficient for activation of sperm flagellar motility.

1986 • 96 citations

How cyclic AMP and its receptor protein act in escherichia coli

1982 • 72 citations

Tissue Distribution and Hormonal Regulation of Messenger Ribonucleic Acid for Regulatory and Catalytic Subunits of Adenosine 3′,5′-Monophosphate Dependent Protein Kinases during Ovarian Follicular Development and Luteinization in the Rat*

1987 • 58 citations

Molecular Mechanisms of Cyclic AMP Action: A Genetic Approach

1976 • 57 citations

Conversion of bovine cardiac adenosine cyclic 3',5'-phosphate dependent protein kinase to a heterodimer by removal of 45 residues at the N-terminus of the regulatory subunit

1986 • 50 citations

Isolation and sequence of a tryptic peptide containing the autophosphorylation site of the regulatory subunit of bovine brain protein kinase II.

1985 • 42 citations

Hotspots for spontaneous and mutagen-induced lesions in regulatory subunit of cyclic AMP-dependent protein kinase in S49 mouse lymphoma cells

1985 • 26 citations