Site-specific mutagenesis of the catalytic subunit of cholera toxin: substituting lysine for arginine 7 causes loss of activity

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Cholera toxin genes: nucleotide sequence, deletion analysis and vaccine development

1983 • 645 citations

Crystal structure of a cholera toxin-related heat-labile enterotoxin from E. coli

1991 • 556 citations

Virulence Factors of Bordetella Pertussis

1986 • 436 citations

Pertussis Toxin Gene: Nucleotide Sequence and Genetic Organization

1986 • 364 citations

Cloning and sequencing of the pertussis toxin genes: operon structure and gene duplication.

1986 • 343 citations

The arrangement of subunits in chlorea toxin

1976 • 337 citations

Adp‐Ribosylation of Guanyl Nucleotide‐Binding Regulatory Proteins by Bacterial Toxins

1988 • 270 citations

Enzymic activity of cholera toxin. II. Relationships to proteolytic processing, disulfide bond reduction, and subunit composition.

1979 • 230 citations

Recombinant nontoxinogenic Vibrio cholerae strains as attenuated cholera vaccine candidates

1984 • 198 citations

Coordinated assembly of multisubunit proteins: oligomerization of bacterial enterotoxins in vivo and in vitro.

1988 • 141 citations

Stimulation of choleragen enzymatic activities by GTP and two soluble proteins purified from bovine brain.

1988 • 141 citations

Pertussis Toxin S1 Mutant with Reduced Enzyme Activity and a Conserved Protective Epitope

1988 • 113 citations

Subunit S1 of pertussis toxin: mapping of the regions essential for ADP-ribosyltransferase activity.

1988 • 105 citations

Effect of site-directed mutagenic alterations on ADP-ribosyltransferase activity of the A subunit of Escherichia coli heat-labile enterotoxin

1991 • 80 citations

Direct Expression of Bordetelia pertussis Toxin Subunits to High Levels in Escherichia coli

1988 • 72 citations

Evolution and structure of two ADP‐ribosylation enterotoxins, Escherichia coli heat‐labile toxin and cholera toxin

1984 • 62 citations

New cholera vaccines

1989 • 54 citations

Role of cholera toxin in enteric colonization by Vibrio cholerae O1 in rabbits

1985 • 51 citations

Identification of a region in the S1 subunit of pertussis toxin that is required for enzymatic activity and that contributes to the formation of a neutralizing antigenic determinant.

1988 • 48 citations

The expression of biologically active cholera toxin inEscherichia coli

1982 • 47 citations

Identification of amino acid residues essential for the enzymatic activities of pertussis toxin.

1989 • 43 citations

ADP-ribosyltransferase activity of mono- and multi-(ADP-ribosylated) choleragen.

1980 • 39 citations

Expression of Pertussis Toxin Correlates with Pathogenesis in Bordetella Species

1989 • 35 citations

Kinetic and hydrodynamic properties of transducin: comparison of physical and structural parameters for GTP-binding regulatory proteins

1987 • 34 citations

Nucleotide sequences within the cholera toxin operon

1983 • 28 citations

Bacterial Toxins and the Role of ADP-Ribosylation

1986 • 22 citations

Photolabelling of mutant forms of the S1 subunit of pertussis toxin with NAD+

1990 • 22 citations

Location and amino acid sequence around the ADP-ribosylation site in the cholera toxin active subunit A1

1983 • 20 citations

Pertussis holotoxoid formed in vitro with a genetically deactivated S1 subunit.

1989 • 19 citations

The Advent of Recombinant Pertussis Vaccines

1990 • 7 citations

Effects of mutations on enzyme activity and immunoreactivity of the S1 subunit of pertussis toxin

1989 • 7 citations