Base selection, proofreading, and mismatch repair during DNA replication in Escherichia coli.

A constant rate of spontaneous mutation in DNA-based microbes.

1991 • 1,194 citations

MECHANISMS AND BIOLOGICAL EFFECTS OF MISMATCH REPAIR

1991 • 876 citations

FIDELITY MECHANISMS IN DNA REPLICATION

1991 • 709 citations

Mechanisms of spontaneous mutagenesis: An analysis of the spectrum of spontaneous mutation in the Escherichia coli lacI gene

1986 • 305 citations

Spectra of spontaneous mutations in Escherichia coli strains defective in mismatch correction: the nature of in vivo DNA replication errors.

1987 • 291 citations

Eukaryotic DNA polymerase amino acid sequence required for 3'----5' exonuclease activity.

1991 • 277 citations

Kinetic partitioning between the exonuclease and polymerase sites in DNA error correction

1991 • 208 citations

Mechanisms of mutagenesis in the Escherichia coli mutator mutD5: role of DNA mismatch repair.

1988 • 203 citations

Spontaneous mutation in the Escherichia coli lacI gene.

1991 • 200 citations

DNA replication fidelity.

1992 • 191 citations

Kinetic basis of spontaneous mutation

1982 • 187 citations

Mutator strains of Escherichia coli, mutD and dnaQ, with defective exonucleolytic editing by DNA polymerase III holoenzyme.

1983 • 174 citations

The extreme mutator effect of Escherichia coli mutD5 results from saturation of mismatch repair by excessive DNA replication errors.

1989 • 149 citations

Construction and characterization of a bacteriophage T4 DNA polymerase deficient in 3'-->5' exonuclease activity.

1993 • 109 citations

Rapid repeated cloning of mutant lac repressor genes

1985 • 101 citations

DNA polymerase III holoenzyme. Components, structure, and mechanism of a true replicative complex.

1991 • 90 citations

Reactions at the polymerase active site that contribute to the fidelity of Escherichia coli DNA polymerase I (Klenow fragment).

1992 • 73 citations

DNA polymerization in the absence of exonucleolytic proofreading: in vivo and in vitro studies.

1991 • 69 citations

The fidelity of base selection by the polymerase subunit of DNA polymerase III holoenzyme

1988 • 64 citations

An Escherichia coli dnaE mutation with suppressor activity toward mutator mutD5

1992 • 48 citations

The mutational specificity of two Escherichia coli dnaE antimutator alleles as determined from lacI mutation spectra.

1993 • 40 citations

Specificity and enzymatic mechanism of the editing exonuclease of Escherichia coli DNA polymerase III.

1991 • 34 citations

Specificity and efficiency of editing of mismatches involved in the formation of base-substitution mutations by the 3'----5' exonuclease activity of phage T4 DNA polymerase.

1987 • 23 citations

Mutations produced by DNA polymerase III holoenzyme of Escherichia coli after in vitro synthesis in the absence of single‐strand binding protein

1990 • 8 citations